Syracuse vs. Clemson Odds & Betting Predictions - September 20, 2025

Syracuse at Clemson

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Syracuse Orange

@

Clemson Tigers

MatchupOpenSpreadTotalMoneyline
Syracuse 2-1	+16.5	+16.5-105	o55.5-105	+520
Clemson 1-2	u55.5	-16.5-115	u55.5-115	-750

location pin

Saturday 4:00 p.m.

September 20, 2025

Memorial Stadium (Clemson, SC)Clemson

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79°Fahrenheit

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37%Rain

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3Wind

No props found

NCAAF Public Betting

Clemson are 1-2 in their last 5 games.
Clemson are 0-3 in their last 5 games against the spread
Clemson are 0-1 in their road games against the spread
The totals have gone OVER in 0 of Clemson' last 3 games
The totals have gone OVER in 0 of Clemson' 2 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Clemson	0-3	0-2	0-1	0-3	N/A
Syracuse	1-1-1	1-0-1	N/A	0-0-1	0-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Clemson	0-3	0-2	0-1	0-3	N/A
Syracuse	2-1	1-1	N/A	0-1	1-0

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Clemson	1-2	N/A	N/A	1-2	N/A
Syracuse	2-1	N/A	N/A	1-0	0-1

date	opponent	score	spread	over/under	moneyline
Sep 13th	@GT	L 21-24	-3 L	U 50.5	GT -145
Sep 6th	TROY	W 27-16	-30.5 L	U 51.5	CLEM -11946
Aug 30th	LSU	L 10-17	-5 L	U 55.5	LSU -205
Dec 21st	@TEX	L 24-38	+13.5 L	O 49.5	TEX +470
Dec 8th	@SMU	W 34-31	+2.5 W	O 56.5	CLEM +111

Total

Passing

1138

YDS

426

83/130

Comps/Atts

37/62

8.75

YPA

6.87

9/3

TDs/INTs

2/2

8/56

Sacks/Yards

3/33

Rushing

320

Rush Yards

151

108

Attempts

51

2.96

YPC

2.96

7

TDs

2

Turnovers

Fumbles Lost

3

Interceptions

2

Efficiency

13/16 81.2%

Redzone

4/5 80%

17/39 0%

3rd Down

8/25 0%

4/7 0%

4th Down

2/5 0%

First Downs

80

Total

30

51

Pass

19

25

Rush

8

4

Penalty

3

Misc

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Penalties/Yards

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See more NCAAF Odds

MatchupOverUnder
Syracuse 2-1	N/A	N/A
Clemson 1-2	N/A	N/A