Hoosiers vs. Purdue Odds & Betting Predictions - February 21, 2026

Hoosiers at Purdue

1:00 am • FOX
64 - 93

Hoosiers at Purdue Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Hoosiers
18-14
+10.5
+11.5-110
o150.5-105
+530
Purdue
23-8
u148.5
-11.5-110
u150.5-112
-800
location pinSaturday 1:00 a.m.
February 21, 2026
Mackey ArenaWest Lafayette
Hoosiers vs. Purdue Expert Picks
John Feltman
John Feltman
Last 30d: 77-72-3 (-2.9u)
Under 157.5 (Live)-118
0.5u
Scott Rickenbach
Scott Rickenbach
Last 30d: 74-83-2 (-16.7u)
IND +11.5-107
1u
Zense
Zense
Last 30d: 2-0-0 (+1.6u)
PUR -10.5-130
0.77u
Allan Lem
Allan Lem
Last 30d: 101-56-2 (+14.3u)
Under 150.5-110
0.55u
Tailing @The_Oddsmaker
John Feltman
John Feltman
Last 30d: 77-72-3 (-2.9u)
Under 150-110
0.55u
Sean Koerner
Sean Koerner
Last 30d: 21-26-2 (-2.4u)
Under 150.5-110
0.55u
Three Man Weave
Three Man Weave
Last 30d: 22-31-0 (-12.0u)
PUR -11.5-110
1u
CTO
CTO
Last 30d: 21-24-0 (+8.6u)
T.Kaufman-Renn o26.5 Pts+Rebs-104
3u
Brian Bitler
Brian Bitler
Last 30d: 85-90-0 (-28.5u)
PUR -11-110
2.73u
Mike Calabrese
Mike Calabrese
Last 30d: 49-47-1 (+16.3u)
PUR -11.5-105
2u
Mackey is going to be on fire for this one. Coming off a humbling loss to Michigan, lost at Assembly Hall to the Hoosiers, this is the spot for a Purdue blowout. Indiana by the way, on the road lost by 20 at Illinois, 14 at Michigan, 21 at Michigan State, 9 at Minnesota. You can beat them up and cover big numbers when they’re on the road. Matt Painter, btw, one of the best coaches in American ATS after a loss. Since he started at Purdue in 2005, he’s covered 56% following a loss, seventh best among Power Conference teams in the past 21 years. Perhaps some three point regression looms for opponents, recent games agaisnst MIchigan and Nebraska those two teams shot 46% from 3PT. Hoosiers made 12 three in their first meeting. A little regression and this could be a runaway.

Hoosiers vs. Purdue Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Hoosiers vs. Purdue Public Betting Percentages

Away Logo

Hoosiers

Public

45%

Bets%

55%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Purdue
13-186-137-510-162-1
Hoosiers
14-189-115-711-93-7

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Purdue
16-1512-74-813-132-1
Hoosiers
14-188-126-610-104-6

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Purdue
23-8N/AN/A19-72-1
Hoosiers
18-14N/AN/A14-62-8

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Feb 17thMICHL 80-91+2.5 LO 156.5MICH +124
Feb 14th@IOWAW 78-57-1.5 WU 142.5PUR -134
Feb 11th@NEBW 80-77+2 WO 146.5PUR +116
Feb 7thOREW 68-64-18.5 LU 144PUR -3500
Feb 1st@MDW 93-63-15.5 WO 148.5PUR -1650

Purdue vs. Hoosiers Injury Updates

Purdue Injuries

    Hoosiers Injuries

    • Jason Drake
      G

      Drake is out with foot

      Out

    • Jordan Rayford
      G

      Rayford is out for season with undisclosed

      Out for Season

    Team Stats
    24-46 (52%)
    Field Goals
    33-51 (65%)
    9-15 (60%)
    Free Throws
    17-25 (68%)
    7-20 (35%)
    3P
    10-18 (56%)
    15
    Rebounds
    29
    13
    Assists
    24
    11
    Turnovers
    6
    0
    Steals
    6
    2
    Blocks
    1
    22
    Fouls
    19

    Hoosiers vs. Purdue Odds Comparison

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    Hoosiers at Purdue Team Totals

    MatchupOverUnder
    Hoosiers
    18-14
    N/A
    N/A
    Purdue
    23-8
    N/A
    N/A