Nittany Lions vs. Ohio State Odds & Betting Predictions - November 1, 2025
Nittany Lions at Ohio State
4:00 pm • FOXNittany Lions at Ohio State Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Nittany Lions 6-6 | +3.5 | +17.5-108 | o44.5-118 | +750 |
 Ohio State 12-0 | u44.5 | -17.5-110 | u44.5-105 | -1200 |
Ohio StadiumColumbus
Nittany Lions vs. Ohio State Expert Picks
Picks Office
Last 30d: 218-161-4 (+38.3u)
PSU +20.5-105
1u
YBK Picks.com
Last 30d: 37-33-1 (+3.4u)
PSU +18.5-105
2u
Dan Gaspar
Last 30d: 54-45-4 (+3.1u)
D.Ross o13.5 Rec Yds-115
1u
Mike Calabrese
Last 30d: 37-49-0 (+2.5u)
OSU -4.5 (1Q)-108
2.78u
The Buckeyes have given up three first-quarter points all season long (1st), a testament to their coaching staff’s preparation. Digging an early hole could force Penn State to throw the ball more with freshman Ethan Grunkemeyer in his second career start.
💰🦡 Jake
Last 30d: 94-111-2 (-9.9u)
PSU +10.5 (1H)-112
1u
Top Shelf Action 🥃
Last 30d: 123-143-11 (-3.5u)
Under 46.5-125
0.5u
Collin Wilson
Last 30d: 90-76-1 (+4.5u)
Over 44-115
1u
Project 53; will discuss on BBOC podcast
Roger Goodell
Last 30d: 43-54-1 (-7.8u)
OSU -20.5-110
0.91u
Mike Calabrese
Last 30d: 37-49-0 (+2.5u)
OSU -20.5-110
2.73u
Ohio State defense is going to eat the Nittany Lions alive 🌰. Ohio State 38 - Penn State 10.
Nittany Lions vs. Ohio State Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Nittany Lions vs. Ohio State Public Betting Percentages
Betting Trends
- Ohio State are 5-0 in their last 5 games.
- Ohio State are 4-1 in their last 5 games against the spread
- Ohio State are 4-1 in their road games against the spread
- The totals have gone OVER in 2 of Ohio State' last 5 games
- The totals have gone OVER in 4 of Ohio State' 7 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 10-3 | 6-1 | 4-1 | 9-3 | N/A |
| 4-8 | 2-5 | 2-3 | 2-4 | 2-1 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 4-9 | 4-3 | 0-5 | 3-9 | N/A |
| 9-3 | 5-2 | 4-1 | 4-2 | 3-0 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 12-0 | N/A | N/A | 11-1 | N/A |
| 6-6 | N/A | N/A | 3-3 | 0-3 |
Last 5 Matchups
Team Stats
200
Total Yards
480
60
Total Plays
55
3.3333333333333335
Yards Per Play
8.727272727272727
145
YDS
316
19/29
Comps/Atts
20/23
5
YPA
13.73913043478261
0/1
TDs/INTs
4/0
4/39
Sacks/Yards
0/0
2/30
Penalties/Yards
2/30
Nittany Lions vs. Ohio State Odds Comparison
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Nittany Lions at Ohio State Team Totals
MatchupOverUnder | ||
|---|---|---|
Nittany Lions 6-6 | o13.5-116 | u13.5-110 |
Ohio State 12-0 | o31.5+100 | u31.5-131 |