Astros vs. Angels Odds & Betting Predictions - June 22, 2025

Astros at Angels

1:38 am • FDSW

Houston Astros

44-32

1 - 7

Los Angeles Angels

36-39

MatchupOpenSpreadTotalMoneyline
Astros 44-32	-1.5	+1.5-194	o8.5-108	+108
Angels 36-39	u8.5	-1.5+168	u8.5-114	-130

Sunday 1:38 a.m.

June 22, 2025

Angel StadiumAnaheim

Under 4.5 (F5)-138

0.5u

Tailing @cawright95

B.Walter o4.5 Ks-110

1.1u

Grabbing this too. Love what we’ve seen from Walter.

Under 4.5 (F5)-138

1.38u

Full writeup: https://www.actionnetwork.com/mlb/houston-astros-vs-los-angeles-angels-prediction-pick-odds-saturday-june-21-qs?utm_source=action_app&utm_medium=app&utm_campaign=article_share

B.Walter o4.5 Ks-118

1.18u

HOU +110

0.5u

Bet to +100

LAA -125

LAA -110

Follow @PicksOffice on X to read the full writeup.

Under 8.5-117

1.17u

B.Walter u17.5 Outs+100

Under 4 (F5)-110

1.1u

B.Walter u4.5 Ks+115

LAA +101

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No props found

MLB Public Betting

Angels are 3-2 in their last 5 games.
Angels are 4-1 in their last 5 games against the spread
Angels are 21-22 in their road games against the spread
The totals have gone OVER in 0 of Angels' last 5 games
The totals have gone OVER in 14 of Angels' 32 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Angels	38-37	17-15	21-22	3-11	34-26
Astros	41-35	22-18	19-17	25-29	16-5

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Angels	37-36-2	14-16-2	23-20	5-8-1	32-27-1
Astros	30-43-3	16-24	14-19-3	25-28-1	4-15-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Angels	36-39	15-17	21-22	8-6	27-33
Astros	44-32	27-13	17-19	32-22	12-9

date	opponent	score	spread	over/under	moneyline
Jun 21st	HOU	L 2-3	+1.5 W	U 8	HOU +141
Jun 19th	@NYY	L 3-7	+1.5 L	U 10.5	NYY +230
Jun 18th	@NYY	W 3-2	+1.5 W	U 9.5	LAA +207
Jun 17th	@NYY	W 4-0	+1.5 W	U 9	LAA +198
Jun 16th	@NYY	W 1-0	+1.5 W	U 8	LAA +165

Jorge Soler
RF
Soler is out with back
Out
Anthony Rendon
3B
Rendon is out with hip
Out

Lance McCullers
SP
Lance McCullers (foot) has been scratched Monday. Ryan Gusto will start for the Astros.
Out
Taylor Trammell
LF
Trammell is out with calf
Out
Cristian Javier
SP
Javier is out with elbow
Out
Luis Garcia
SP
Garcia is out with elbow
Out
Pedro Leon
RF
Leon is out with knee
Out
J.P. France
SP
France is out with shoulder
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out
Spencer Arrighetti
SP
Arrighetti is out with thumb
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
LB.Walter, P		99	6	6	7
RK.Ort, P		6	0	0	0

HITTERS	H-AB	R	RBI
1J.Pena, SS	0-3	0	0
2I.Paredes, 3B	1-3	0	0
3J.Altuve, LF	0-0	1	0
4Y.Diaz, C	0-3	0	0
5C.Smith, RF	0-3	0	0
6C.Walker, 1B	1-3	0	1
7V.Caratini, DH	0-3	0	0
8J.Meyers, CF	1-3	0	0
9L.Guillorme, 2B	0-3	0	0

PITCHER		PC	IP	K	ER
RJ.Soriano, P		96	6.2	10	1
RH.Neris, P		4	0.1	1	0

HITTERS	H-AB	R	HR	RBI
1Z.Neto, SS	2-4	1	0	0
2N.Schanuel, 1B	2-3	1	0	1
3M.Trout, DH	1-4	1	0	0
4T.Ward, LF	1-3	1	0	2
5L.O'Hoppe, C	1-3	1	1	2
6J.Adell, CF	1-2	1	0	0
7L.Rengifo, 3B	1-3	1	1	2
8G.Campero, RF	0-3	0	0	0
9C.Moore, 2B	0-3	0	0	0