Toledo vs. Louisville Odds & Betting Predictions - December 23, 2025

Toledo at Louisville

7:00 pm • ESPN

Toledo Rockets

@

Louisville Cardinals

MatchupOpenSpreadTotalMoneyline
Toledo 8-4	+8.5	+8.5-115	o45.5-110	+260
Louisville 8-4	u45.5	-8.5-105	u45.5-115	-325

location pin

Tuesday 7:00 p.m.

December 23, 2025

Flagler Credit Union StadiumBoca Raton

No props found

NCAAF Public Betting

Louisville are 3-2 in their last 5 games.
Louisville are 2-3 in their last 5 games against the spread
Louisville are 3-1 in their road games against the spread
The totals have gone OVER in 2 of Louisville' last 5 games
The totals have gone OVER in 4 of Louisville' 8 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Louisville	4-8	1-7	3-1	2-7	2-1
Toledo	8-4	5-1	3-3	7-4	1-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Louisville	5-7	4-4	1-3	5-4	0-3
Toledo	6-6	5-1	1-5	6-5	0-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Louisville	8-4	N/A	N/A	6-3	2-1
Toledo	8-4	N/A	N/A	8-3	0-1

date	opponent	score	spread	over/under	moneyline
Nov 29th	UK	W 41-0	+1 W	U 45.5	-
Nov 22nd	@SMU	L 6-38	+3.5 L	U 49.5	SMU +154
Nov 15th	CLEM	L 19-20	-1.5 L	U 51	CLEM -125
Nov 9th	CAL	L 26-29	-18.5 L	O 48.5	CAL -1100
Nov 1st	@VT	W 28-16	-10.5 W	U 52.5	LOU -395

Total

Passing

2928

YDS

2715

239/371

Comps/Atts

252/394

7.89

YPA

6.89

26/10

TDs/INTs

16/9

14/110

Sacks/Yards

23/165

Rushing

2141

Rush Yards

1951

432

Attempts

385

4.96

YPC

5.07

21

TDs

23

Turnovers

Fumbles Lost

10

Interceptions

9

Efficiency

37/49 75.5%

Redzone

35/38 92.1%

66/161 0%

3rd Down

58/158 0%

3/16 0%

4th Down

6/11 0%

First Downs

255

Total

235

137

Pass

117

103

Rush

99

15

Penalty

19

Misc

/

Penalties/Yards

/

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MatchupOverUnder
Toledo 8-4	N/A	N/A
Louisville 8-4	N/A	N/A