Chiefs vs. Bills Odds & Betting Predictions - November 2, 2025

Chiefs at Bills

9:25 pm • CBS
@

Chiefs at Bills Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Chiefs
3-3
N/A
N/A
N/A
Bills
4-2
N/A
N/A
N/A
location pinSunday 9:25 p.m.
November 02, 2025
Highmark StadiumOrchard Park

Chiefs vs. Bills Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Chiefs vs. Bills Public Betting Percentages

Away Logo

Chiefs

Public

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Bills
2-41-31-11-41-0
Chiefs
3-32-11-12-21-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Bills
3-33-10-22-31-0
Chiefs
3-31-21-12-21-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Bills
4-2N/AN/A3-21-0
Chiefs
3-3N/AN/A2-21-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 13th@ATLL 14-24-3.5 LU 49.5ATL -202
Oct 6thNEL 20-23-7.5 LU 48.5NE -430
Sep 28thNOW 31-19-14.5 LO 48.5BUF -1500
Sep 19thMIAW 31-21-11.5 LO 50.5BUF -800
Sep 14th@NYJW 30-10-6 WU 47.5BUF -290

Chiefs vs. Bills Injury Updates

Chiefs Injuries

    Bills Injuries

    • Curtis Samuel
      WR

      Samuel is questionable with ribs

      Questionable

    • Mitch Wishnowsky
      P

      Wishnowsky is out with back

      Out

    • Tyler Bass
      K

      Bass is out with hip

      Out

    • Dalton Kincaid
      TE

      Kincaid is questionable with oblique

      Questionable

    Player Stats
    • passing yards
      Josh Allen logo
      Josh Allen
      1397
      pyds
    • passing touchdowns
      Josh Allen logo
      Josh Allen
      11
      ptd
    • rushing yards
      James Cook logo
      James Cook
      537
      ryds
    • rushing touchdowns
      James Cook logo
      James Cook
      5
      rtd
    Depth Charts
    Right Arrow
    Starter2ND3RD4TH
    QBJosh AllenMitchell TrubiskyShane Buechele
    RBJames CookRay DavisTy JohnsonFrank Gore
    WRKhalil ShakirElijah MooreStephen Gosnell
    TEDalton KincaidDawson KnoxJackson HawesKeleki Latu
    LTDion DawkinsTylan GrableChase LundtTravis Clayton
    LGDavid EdwardsKendrick Green
    CConnor McGovernSedrick Van Pran-Granger
    RGO'Cyrus TorrenceAlec Anderson
    RTSpencer BrownRyan Van Demark
    LDEGreg RousseauLandon JacksonJavon Solomon
    WLBMatt MilanoDorian WilliamsKeonta Jenkins
    MLBTerrel BernardJoe AndreessenShaq ThompsonJimmy Ciarlo
    LCBChristian BenfordMaxwell HairstonDorian Strong
    SSCole BishopCam LewisWande Owens
    FSTaylor RappDamar HamlinJordan Hancock
    RCBTre'Davious WhiteDane JacksonJa'Marcus Ingram
    PRBrandon Codrington
    KRBrandon CodringtonElijah Moore
    LSReid Ferguson
    FBReggie Gilliam
    LWRJoshua PalmerTyrell Shavers
    KTyler Bass
    RWRKeon ColemanCurtis SamuelKristian Wilkerson
    NTDaQuan JonesDeone WalkerZion Logue
    NBTaron JohnsonBrandon Codrington
    DTEd OliverT.J. SandersDeWayne Carter
    Team Stats
    1448
    YDS
    1364
    138/213
    Comps/Atts
    123/180
    7.108
    YPA
    7.939
    11/2
    TDs/INTs
    11/4
    10/66
    Sacks/Yards
    12/65
    712
    Rush Yards
    906
    154
    Attempts
    186
    4.623
    YPC
    4.871
    7
    TDs
    9

    Turnovers

    Fumbles Lost
    2
    Interceptions
    4

    Efficiency

    16/25 64%
    Redzone
    16/25 64%
    31/75 0%
    3rd Down
    28/68 0%
    11/13 0%
    4th Down
    3/5 0%

    First Downs

    133
    Total
    139
    75
    Pass
    73
    50
    Rush
    50
    8
    Penalty
    16
    /
    Penalties/Yards
    /
    Possession

    Chiefs vs. Bills Odds Comparison

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    Chiefs at Bills Team Totals

    MatchupOverUnder
    Chiefs
    3-3
    N/A
    N/A
    Bills
    4-2
    N/A
    N/A