Falcons vs. Cardinals Odds & Betting Predictions - December 21, 2025

Falcons at Cardinals

9:05 pm • FOX

Atlanta Falcons

6-9

26 - 19

Arizona Cardinals

3-12

MatchupOpenSpreadTotalMoneyline
Falcons 6-9	+3.5	-2.5-112	o48.5-112	-150
Cardinals 3-12	u46.5	+2.5-108	u48.5-110	+125

Sunday 9:05 p.m.

December 21, 2025

State Farm StadiumGlendale

ARI +3.5-130

0.4u

Boyd / FanDuel

ATL -2.5-110

0.91u

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Under 48.5-105

0.95u

ATL -3+100

1.25u

ATL -3-105

1.9u

ARI +3-110

1.1u

J.Brissett o12.5 Rush Yds-110

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B.Robinson 100+ Rushing Yards Yes+140

J.Brissett 350+ Passing Yards Yes+900

0.1u

J.Brissett o250.5 Pass Yds-115

0.57u

J.Brissett 275+ Passing Yards Yes+150

0.1u

J.Brissett 300+ Passing Yards Yes+270

0.1u

J.Brissett 325+ Passing Yards Yes+500

0.1u

Over 48-120

1.2u

J.Brissett u258.5 Pass Yds-115

C.Kiner Anytime TD Scorer Yes+900

0.5u

@The_Oddsmaker https://myaction.app/yPjwhrUIeZb

T.Allgeier Anytime TD Scorer Yes+150

0.5u

@The_Oddsmaker https://myaction.app/yPjwhrUIeZb

Over 45.5-108

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Over 45.5-110

🔥 Week 16 Hot Read 🔥

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NFL Public Betting

Cardinals are 1-4 in their last 5 games.
Cardinals are 3-2 in their last 5 games against the spread
Cardinals are 5-2 in their road games against the spread
The totals have gone OVER in 2 of Cardinals' last 5 games
The totals have gone OVER in 6 of Cardinals' 8 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	6-9	1-7	5-2	1-2	5-7
Falcons	8-7	2-4	5-3	2-5	6-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	9-6	6-2	3-4	2-1	7-5
Falcons	7-8	3-3	3-5	3-4	4-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	3-12	N/A	N/A	2-1	1-11
Falcons	6-9	N/A	N/A	2-5	4-4

date	opponent	score	spread	over/under	moneyline
Dec 14th	@HOU	L 20-40	+10.5 L	O 42.5	HOU +452
Dec 7th	LA	L 17-45	+9.5 L	O 49.5	LA +372
Nov 30th	@TB	L 17-20	+4.5 W	U 45.5	TB +185
Nov 23rd	JAC	L 24-27	+2.5 L	O 47.5	JAC +114
Nov 16th	SF	L 22-41	+3.5 L	O 48.5	SF +157

KhaDarel Hodge
WR
Hodge is out with shoulder
Out
Michael Penix
QB
Penix is out with knee
Out

Zay Jones
WR
Jones is out with achilles
Out
James Conner
RB
Conner is out with foot
Out
Greg Dortch
WR
Dortch is out with chest
Out
Kyler Murray
QB
Murray is out with foot
Out
Andre Baccellia
WR
Baccellia is out with neck
Out
Bam Knight
RB
Knight is out with ankle
Out
Trey Benson
RB
Benson is out with knee
Out
Tip Reiman
TE
Reiman is out with ankle
Out

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Falcons

Total

Cardinals

342

Total Yards

320

Total Plays

4.7

Yards Per Play

5.7

Falcons

Passing

Cardinals

197

YDS

203

21/35

Comps/Atts

16/31

5.278

YPA

5.697

2/1

TDs/INTs

1/1

1/7

Sacks/Yards

2/15

Falcons

Rushing

Cardinals

152

Rush Yards

132

Attempts

4.108

YPC

5.739

TDs

Falcons

Turnovers

Cardinals

Fumbles Lost

Interceptions

Falcons

Efficiency

Cardinals

3/3 100%

Redzone

0/2 0%

7/14 0%

3rd Down

7/13 0%

2/5 0%

4th Down

0/0 0%

Falcons

First Downs

Cardinals

Total

Pass

Rush

Penalty

Falcons

Misc

Cardinals

4/20

Penalties/Yards

5/14

35:34

Possession

24:26

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MatchupOverUnder
Falcons 6-9	o24.5-115	u24.5-115
Cardinals 3-12	o23.5-110	u23.5-115

Falcons vs. Cardinals Odds & Betting Predictions - December 21, 2025

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Falcons vs. Cardinals Public Betting Percentages

Falcons

Public

Cardinals

Bets%

Money%

Betting Trends

Matchup History

Against the Spread (ATS) History

Over/Under History

Straight-Up (ML) History

Last 5 Matchups

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Falcons Injuries

Cardinals Injuries

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