Duke vs. Clemson Odds & Betting Predictions - November 1, 2025
Duke at Clemson
4:00 pm • ACC NetworkDuke at Clemson Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Duke 9-5 | +2.5 | +4-110 | o54.5-115 | +155 |
Clemson 7-6 | u53.5 | -4-110 | u54.5-115 | -188 |

Memorial Stadium (Clemson, SC)Clemson
Duke vs. Clemson Expert Picks
The Propfessor
Last 30d: 56-49-0 (+12.1u)
A.Williams o4.5 Recs-145
0.69u
Brian Bitler
Last 30d: 92-93-1 (-21.8u)
DUKE +3.5-105
2.86u
Dan Gaspar
Last 30d: 0-0-0 (+0.0u)
Q.Brown o44.5 Rec Yds-114
1u
Jeremiah Rose
Last 30d: 22-11-0 (+12.1u)
DUKE +4-110
0.36u
Boomer’s Book
Top Shelf Action 🥃
Last 30d: 140-151-0 (-27.1u)
CLEM -2.5-136
0.6u
Duke vs. Clemson Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Duke vs. Clemson Public Betting Percentages
Betting Trends
- Clemson are 2-3 in their last 5 games.
- Clemson are 1-4 in their last 5 games against the spread
- Clemson are 4-1 in their road games against the spread
- The totals have gone OVER in 3 of Clemson' last 5 games
- The totals have gone OVER in 3 of Clemson' 7 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
361
YDS
385
27/42
Comps/Atts
27/36
8.595238095238095
YPA
10.694444444444445
4/0
TDs/INTs
2/0
2/15
Sacks/Yards
1/6
Duke vs. Clemson Odds Comparison
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Duke at Clemson Team Totals
MatchupOverUnder | ||
|---|---|---|
Duke 9-5 | N/A | N/A |
Clemson 7-6 | N/A | N/A |






