SMU vs. Clemson Odds & Betting Predictions - October 18, 2025

SMU at Clemson

7:30 pm • ACC Network

SMU Mustangs

@

Clemson Tigers

MatchupOpenSpreadTotalMoneyline
SMU 4-2	+11.5	+9.5-112	o55.5-102	+270
Clemson 3-3	u55.5	-9.5-108	u55.5-115	-345

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Saturday 7:30 p.m.

October 18, 2025

Memorial Stadium (Clemson, SC)Clemson

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77°Fahrenheit

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0%Rain

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8Wind

CLEM -8.5-110

1u

No props found

NCAAF Public Betting

Clemson are 2-3 in their last 5 games.
Clemson are 1-4 in their last 5 games against the spread
Clemson are 2-1 in their road games against the spread
The totals have gone OVER in 1 of Clemson' last 5 games
The totals have gone OVER in 1 of Clemson' 3 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Clemson	2-4	0-3	2-1	2-4	N/A
SMU	1-5	1-3	0-2	1-3	0-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Clemson	2-4	1-2	1-2	2-4	N/A
SMU	1-5	1-3	0-2	1-3	0-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Clemson	3-3	N/A	N/A	3-3	N/A
SMU	4-2	N/A	N/A	3-1	0-1

date	opponent	score	spread	over/under	moneyline
Oct 11th	@BC	W 41-10	-14 W	U 54.5	CLEM -590
Oct 4th	@UNC	W 38-10	-15.5 W	O 47.5	CLEM -720
Sep 20th	SYR	L 21-34	-17.5 L	O 53.5	SYR -900
Sep 13th	@GT	L 21-24	-3 L	U 50.5	GT -145
Sep 6th	TROY	W 27-16	-30.5 L	U 51.5	CLEM -11946

Total

Passing

1667

YDS

1673

138/192

Comps/Atts

142/221

8.68

YPA

7.57

15/6

TDs/INTs

12/6

11/124

Sacks/Yards

7/52

Rushing

762

Rush Yards

780

190

Attempts

182

4.01

YPC

4.29

9

TDs

8

Turnovers

Fumbles Lost

6

Interceptions

6

Efficiency

16/19 84.2%

Redzone

14/19 73.7%

28/74 0%

3rd Down

28/74 0%

6/8 0%

4th Down

10/19 0%

First Downs

129

Total

127

67

Pass

73

48

Rush

45

14

Penalty

9

Misc

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Penalties/Yards

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See more NCAAF Odds

MatchupOverUnder
SMU 4-2	N/A	N/A
Clemson 3-3	N/A	N/A