Cardinals vs. Seahawks Odds & Betting Predictions - November 9, 2025

Cardinals at Seahawks

9:05 pm • CBS

Arizona Cardinals

Seattle Seahawks

MatchupOpenSpreadTotalMoneyline
Cardinals 3-5	+1.5	+6.5-105	o45.5-110	+245
Seahawks 6-2	u45.5	-6.5-115	u45.5-110	-310

Sunday 9:05 p.m.

November 09, 2025

Lumen FieldSeattle

58°Fahrenheit

0%Rain

3Wind

Over 44.5-115

The Seahawks showed they can light it up even without Cooper Kupp, and the Cardinals' offense has shown life with Jacoby Brissett. Even if they go back to Kyler Murray, I don't think that'd ding this total. I have it at 47.7.

Over 46.5+106

0.7u

3% ev play to +100

Under 45.5-110

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NFL Public Betting

Seahawks are 3-2 in their last 5 games.
Seahawks are 3-2 in their last 5 games against the spread
Seahawks are 4-0 in their road games against the spread
The totals have gone OVER in 2 of Seahawks' last 5 games
The totals have gone OVER in 3 of Seahawks' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Seahawks	6-2	2-2	4-0	5-1	1-1
Cardinals	5-3	1-3	4-0	1-2	4-1

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Seahawks	5-3	3-1	2-2	4-2	1-1
Cardinals	4-4	3-1	1-3	2-1	2-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Seahawks	6-2	N/A	N/A	5-1	1-1
Cardinals	3-5	N/A	N/A	2-1	1-4

date	opponent	score	spread	over/under	moneyline
Nov 3rd	@WAS	W 38-14	-2.5 W	O 47.5	SEA -148
Oct 21st	HOU	W 27-19	-3 W	O 41.5	SEA -168
Oct 12th	@JAC	W 20-12	-1.5 W	U 47.5	SEA -116
Oct 5th	TB	L 35-38	-3.5 L	O 44.5	TB -194
Sep 26th	@ARI	W 23-20	-1.5 W	U 43.5	SEA -120

Cooper Kupp
WR
Kupp is questionable with heel
Questionable

Uchenna Nwosu
LB
Nwosu is out with knee
Out

James Conner
RB
Conner is out with foot
Out
Kyler Murray
QB
Murray is out with foot
Out
Owen Pappoe
LB
Pappoe is questionable with quad
Questionable
Trey Benson
RB
Benson is out with knee
Out
Tip Reiman
TE
Reiman is out with ankle
Out

See more NFL Injuries

passing yards
Sam Darnold
2084
pyds
passing touchdowns
Sam Darnold
16
ptd
rushing yards
Kenneth Walker
472
ryds
rushing touchdowns
Zach Charbonnet
5
rtd

	Starter	2ND	3RD	4TH
QB	Sam Darnold	Drew Lock	Jalen Milroe
RB	Kenneth Walker	Zach Charbonnet	George Holani	Jacardia Wright
WR	Cooper Kupp	Dareke Young
TE	AJ Barner	Elijah Arroyo	Eric Saubert	Nick Kallerup
LT	Charles Cross	Amari Kight
LG	Grey Zabel	Bryce Cabeldue
C	Olu Oluwatimi	Jalen Sundell	Federico Maranges
RG	Anthony Bradford	Christian Haynes	Mason Richman
RT	Abraham Lucas	Josh Jones
LDE	DeMarcus Lawrence	Derick Hall	Jared Ivey	Connor O'Toole
RDE	Leonard Williams	Mike Morris	J.R. Singleton
WLB	Tyrice Knight	Patrick O'Connell	Jamie Sheriff
MLB	Ernest Jones	Drake Thomas
LCB	Josh Jobe	Nehemiah Pritchett	Shemar Jean-Charles
SS	Julian Love	Nick Emmanwori	Jerrick Reed
FS	Coby Bryant	D'Anthony Bell	Ty Okada
RCB	Riq Woolen	Shaquill Griffin
P	Michael Dickson
H	Michael Dickson
PR	Tory Horton
KR	Tory Horton	Zach Charbonnet
LS	Chris Stoll
FB	Robbie Ouzts	Brady Russell
NB	Devon Witherspoon
DT	Jarran Reed	Rylie Mills
LWR	Jaxon Smith-Njigba	Jake Bobo	Cody White	Tyrone Broden
K	Jason Myers
NT	Byron Murphy	Johnathan Hankins	Brandon Pili	Quinton Bohanna
RWR	Tory Horton	Ricky White
ROLB	Jamie Sheriff	Connor O'Toole
LOLB	Uchenna Nwosu	Boye Mafe