Cowboys vs. Panthers Odds & Betting Predictions - October 12, 2025

Cowboys at Panthers

5:00 pm • FOX
27 - 30

Cowboys at Panthers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cowboys
3-3-1
-1.5
-3+100
o47-110
-160
Panthers
4-3
u46.5
+3-110
u47-112
+135
location pinSunday 5:00 p.m.
October 12, 2025
Bank of America StadiumCharlotte
Cowboys vs. Panthers Expert Picks
Greg Matherne
Greg Matherne
Last 30d: 36-49-2 (+0.3u)
Under 46.5-105
0.55u
The Degenerates
The Degenerates
Last 30d: 66-57-2 (+4.6u)
DAL -3-109
1.09u
Ryan Sura
Ryan Sura
Last 30d: 98-104-1 (-4.9u)
J.Tolbert o28.5 Rec Yds-130
1.3u
YBK Picks.com
Last 30d: 61-38-3 (+42.3u)
CAR +3-105
1.9u
Capper Central
Capper Central
Last 30d: 83-69-1 (-2.5u)
CAR +3+100
1u
Babs .
Babs .
Last 30d: 96-101-3 (-2.1u)
B.Young u209.5 Pass Yds-111
0.9u
Austin Pendergrass
Austin Pendergrass
Last 30d: 47-47-1 (-1.8u)
DAL -158
1u
Vegas Refund
Vegas Refund
Last 30d: 44-37-3 (+3.6u)
CAR +3-110
1u
Picks Office
Picks Office
Last 30d: 86-71-2 (+11.3u)
CAR +3-105
0.95u
X: @PicksOffice
Chris Raybon
Chris Raybon
Last 30d: 25-35-1 (-6.6u)
Under 49-115
1u
Matt DiLeo
Matt DiLeo
Last 30d: 41-32-0 (+4.6u)
Cowboys Longest FG-105
1u
Derek Carty
Derek Carty
Last 30d: 25-26-0 (+4.4u)
J.Williams u2.5 Recs+145
1u
THE BLITZ is forecasting 2.53 receptions for Javonte Williams compared to 3.53 receptions implied by sportsbooks, so I believe there is some value here. If you take the under, you’d be projected to win 58% of the time, resulting in a 38% ROI. Based on a $100 wager, the expected value here would be $38.07. (This play is good down to at least +100.) Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Brandon Kravitz
Brandon Kravitz
Last 30d: 64-81-1 (-7.3u)
CAR +3+100
1u
Adding to my position
Allan Lem
Allan Lem
Last 30d: 139-99-6 (+16.1u)
B.Young u213.5 Pass Yds-115
0.5u
Tailing @The_Oddsmaker. Can get u216.5 on Sleeper if you play there.
Sean Koerner
Sean Koerner
Last 30d: 50-37-0 (+7.7u)
B.Young u213.5 Pass Yds-115
0.5u
The weather report for this game has gotten significantly worse and we are close enough to kickoff to feel pretty confident there will be showers at times and high winds (20+). Starting to see markets adjust and I think Young’s pass yds prop should see the biggest hit due to the weather. He’s getting a big boost due to Dallas 32nd ranked pass DVOA, but this is a game Car will be able to lean on the run and keep things close. Projecting him closer to 195.5 based on the recent weather forecast
Chris Gimino
Chris Gimino
Last 30d: 32-41-1 (-5.6u)
B.Young o31.5 Pass Att-110
1u
Brandon Anderson
Brandon Anderson
Last 30d: 52-99-0 (-3.1u)
T.McMillan Anytime TD Scorer Yes+150
1.35u
For a second straight week, I strongly considered the Cowboys as a short road favorite. This Dallas offense looks legit, and Dak Prescott is typically great as a favorite and against sub-.500 teams. The Cowboys should score. But they might allow plenty of points to the Panthers too, as bad as their defense is playing, and with a total at 49.5, this could end up in the running for highest-scoring game of the week. Could this finally be the Tet McMillan breakout game? Carolina's star rookie WR has looked the part on the field but yet to put up a huge line, but this matchup sets up well for some big time production. The Cowboys rank bottom three in the NFL both against the pass and overall by Defensive DVOA. This pass defense just has no shot right now, especially against opposing WR1s. Malik Nabers had nine catches for 167 yards and two scores against Dallas. Rome Odunze had 62 yards and a TD. Romeo Doubs found the end zone three times, and Garrett Wilson saw 71 yards and a score himself. All four of those WRs scored a touchdown, with Nabers scoring twice and Doubs three times. Dallas allowed a TD to 8-of-17 opposing WR1s last season too, almost half of them. McMillan's receptions and yardage lines have been bet up this week past value, so I'm investing in a touchdown or two. He's a big target and should be Bryce Young's look in the red zone, and we could see a whole bunch of touchdowns in a potential shootout. I'll back McMillan for an Anytime Touchdown at +150 (Caesars) and put a bit on two TDs at +1200 too (FanDuel) with plenty of scores to go around. This might also be the spot to buy a Tet McMillan ticket for Offensive Rookie of the Year at +1300 (ESPN Bet). Emeka Egbuka is the clear favorite right now but should slow down once Mike Evans and Chris Godwin return, and the field looks pretty wide open after Egbuka with Ashton Jeanty second in name only. A big game Sunday from McMillan should finally get him the attention he deserves.
T.McMillan 2+ TDs Yes+1200
1.2u
Markus Markets
Markus Markets
Last 30d: 37-30-0 (+5.8u)
R.Dowdle o13.5 Rec Yds-108
0.93u
Brandon Kravitz
Brandon Kravitz
Last 30d: 64-81-1 (-7.3u)
R.Dowdle Anytime TD Scorer Yes-120
0.5u
Roger Goodell
Roger Goodell
Last 30d: 53-32-3 (+16.0u)
J.Ferguson o46.5 Rec Yds-114
0.5u
TAN Pod Touchdown Show
TAN Pod Touchdown Show
Last 30d: 14-49-1 (-4.4u)
R.Flournoy Anytime TD Scorer Yes+310
0.5u
J.Horn Anytime TD Scorer Yes+1000
0.5u
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 67-118-0 (-1.9u)
T.McMillan 2+ TDs Yes+1200
1.2u
T.McMillan Anytime TD Scorer Yes+150
1.5u
Gilles Gallant
Gilles Gallant
Last 30d: 26-87-1 (-17.2u)
B.Young o0.5 Int-103
0.5u
NFL INT Picks - W6
Matt DiLeo
Matt DiLeo
Last 30d: 41-32-0 (+4.6u)
J.Ferguson o46.5 Rec Yds-114
1u
Boomer Betz
Boomer Betz
Last 30d: 174-163-3 (+11.9u)
J.Williams u79.5 Rush Yds-113
0.88u
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 67-118-0 (-1.9u)
Under 49.5-108
1u
@ChrisRaybon Favorite Total https://myaction.app/5p3LFPuxkXb
CAR +3+100
1u
@sundaysixpack @ChrisRaybon https://myaction.app/S6McBO2wkXb
Sunday Six Pack
Sunday Six Pack
Last 30d: 15-15-0 (-1.7u)
CAR +3+100
1u
Derek Carty
Derek Carty
Last 30d: 25-26-0 (+4.4u)
R.Flournoy u44.5 Rec Yds-110
1u
THE BLITZ is forecasting 32.48 receiving yards for Ryan Flournoy compared to 50.35 receiving yards implied by sportsbooks, so I believe there is some value here. If you take the under, you’d be projected to win 73% of the time, resulting in a 39% ROI. Based on a $100 wager, the expected value here would be $43.71. (This play is good down to at least -176.) Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Kenny Ducey
Kenny Ducey
Last 30d: 27-23-1 (+1.9u)
DAL -3-114
1.14u
💰🦡 Jake
💰🦡 Jake
Last 30d: 110-133-5 (+14.4u)
X.Legette Anytime TD Scorer Yes+300
0.1u
Chris Raybon
Chris Raybon
Last 30d: 25-35-1 (-6.6u)
CAR +3.5-120
0.83u
#SundaySixPack
Boomer Betz
Boomer Betz
Last 30d: 174-163-3 (+11.9u)
DAL u26.5 Team Total+106
1u
Bet105
Stuck 🚨
Stuck 🚨
Last 30d: 65-71-2 (+0.9u)
CAR +3+100
0.4u
Matt Moore
Matt Moore
Last 30d: 15-18-0 (-1.7u)
CAR +3-102
1.08u
Kendra Middleton
Kendra Middleton
Last 30d: 15-8-0 (+8.2u)
DAL -3.5+110
1u
Brandon Kravitz
Brandon Kravitz
Last 30d: 64-81-1 (-7.3u)
CAR +170
0.68u
CAR +3+100
1u
Plant the Flag! ⛳️ @TheFavoritesPodcast my power ratings make this Cowboys -1. So I like that first and foremost. But as I’ve mentioned, my numbers are far from gospel. Its more of a guide to get me pointed in the right direction. The Cowboys are playing their 3rd road game in their past 4 games, big divisional matchup with Washington on deck…Carolina is parked at home, we’ve got a Rico Dowdle revenge game (kidding, sort of)…the Cowboys have the worst graded run D in the NFL – taking on a guy that just rumbled for 200 yards and used to play for the team. Its at least enough to get me to the window. Do keep in mind, CeeDee Lamb might be back – that would push this line to 4/4.5 – I’ll take the even money at +3 and avoid the juice of the 3.5.

Cowboys vs. Panthers Previews & Analysis

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Cowboys vs. Panthers Props

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Cowboys vs. Panthers Public Betting Percentages

Away Logo

Cowboys

Public

73%

Bets%

27%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Panthers
5-23-02-2N/A5-2
Cowboys
4-32-12-21-33-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Panthers
4-32-12-2N/A4-3
Cowboys
5-23-02-23-12-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Panthers
4-3N/AN/AN/A4-3
Cowboys
3-3-1N/AN/A2-21-1-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 5thMIAW 27-24+1.5 WO 44.5CAR -102
Sep 28th@NEL 13-42+5.5 LO 42.5NE +200
Sep 21stATLW 30-0+4.5 WU 44CAR +185
Sep 14th@ARIL 22-27+7 WO 45.5ARI +265
Sep 7th@JACL 10-26+4.5 LU 45.5JAC +184

Cowboys vs. Panthers Injury Updates

Cowboys Injuries

  • Miles Sanders
    RB

    Sanders is out with ankle

    Out

  • Perrion Winfrey
    DT

    Winfrey is out with back

    Out

  • Jonathan Mingo
    WR

    Mingo is out with knee

    Out

Panthers Injuries

  • David Moore
    WR

    Moore is out with elbow

    Out

  • Damarri Mathis
    CB

    Mathis is out with knee

    Out

Team Stats
292
Total Yards
410
53
Total Plays
64
5.5
Yards Per Play
6.4
261
YDS
199
25/34
Comps/Atts
17/25
7.676
YPA
7.462
3/0
TDs/INTs
3/1
0/0
Sacks/Yards
1/5
31
Rush Yards
216
19
Attempts
38
1.632
YPC
5.684
0
TDs
0
0
Fumbles Lost
0
0
Interceptions
1

Efficiency

2/4 50%
Redzone
2/4 50%
5/12 0%
3rd Down
3/8 0%
2/2 0%
4th Down
1/1 0%

First Downs

15
Total
27
12
Pass
11
1
Rush
14
2
Penalty
2
6/37
Penalties/Yards
6/57
27:58
Possession
32:02

Cowboys vs. Panthers Odds Comparison

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Cowboys at Panthers Team Totals

MatchupOverUnder
Cowboys
3-3-1
o25-106
u25-117
Panthers
4-3
o22.5-116
u22.5-107