Rams vs. Jaguars Odds & Betting Predictions - October 19, 2025
Rams at Jaguars
1:30 pm • NFL NetworkRams at Jaguars Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Rams 5-2 | -3.5 | -3-115 | o44.5-105 | -166 |
![]() Jaguars 4-3 | u47.5 | +3-105 | u44.5-115 | +142 |

Wembley StadiumLondon
Rams vs. Jaguars Expert Picks

Moneyline Hacks
Last 30d: 110-112-3 (+47.6u)
D.Adams 25+ Receiving Yards Yes (Live)+1450
21.75u
🚨Free analysis & VIP Picks can be found on our Discord. Link: https://discord.gg/JrzjtqdVfA
🎙️Fade the Noise PODCAST - Subscribe!✅
https://www.youtube.com/@FadetheNoise
🔥50% OFF VIP!! ⬇️⬇️ (COPY & PASTE LINK):
https://dubclub.win/r/p/pri-r744p/?checkout=1&coupon=ValueHacks50
B.Thomas 25+ Receiving Yards Yes (Live)-1250
0.12u
🚨Free analysis & VIP Picks can be found on our Discord. Link: https://discord.gg/JrzjtqdVfA
🎙️Fade the Noise PODCAST - Subscribe!✅
https://www.youtube.com/@FadetheNoise
🔥50% OFF VIP!! ⬇️⬇️ (COPY & PASTE LINK):
https://dubclub.win/r/p/pri-r744p/?checkout=1&coupon=ValueHacks50

Greg Matherne
Last 30d: 36-49-2 (+0.3u)
Under 44.5-110
0.5u

PvB Bets
Last 30d: 7-1-0 (+5.0u)
J.Whittington o3.5 Recs-114
1u
Jordan Whittington ⬆️ 3.5 Receptions (-114 @ FanDuel)(LAR)
With Puka Nacua sidelined due to an ankle injury, Whittington is poised to step into an expanded role within the Rams' passing game. His snap count has already been trending upward, and without Nacua, he's set for his highest usage of the season. He's demonstrated his capability with 2+ receptions in four of his last five games, and last week, he saw four targets even in a relatively low-scoring game against a depleted Ravens team.
The upcoming matchup against the Jacksonville Jaguars is also a plus spot for Jordan. Jacksonville utilizes zone coverage at one of the highest rates in the league (79.7%). Here is hoe Whittington has done against zone and man:
**Vs Zone: 7.6% target rate, 80.0% catch rate and 8.6% 1st read rate**
Vs Man: 4.5 % target rate, 66.7% catch rate and 3.6% 1st read rate
Furthermore, the Jaguars' have a good run defense, which ranks 12th in the league and hasn't allowed any opposing running back over 60 rushing yards this season, which will likely force the Rams to lean heavily on their passing game. This looks like a great spot for Whittington to step up in Nacua's absence.

Sir Lockselot
Last 30d: 31-61-0 (-17.2u)
JAC +140
2u
📚Player Profit
🔑 Jaguars ML +140 (Player Profit) 2u
Jags are London’s team. Getting to face a banged up Rams team without Puka. Love this spot for Jacksonville to get it done.

Picks Office
Last 30d: 86-71-2 (+11.3u)
Under 44.5-105
0.95u

Sandy Plashkes
Last 30d: 99-101-2 (+13.1u)
T.Hunter o41.5 Rec Yds-112
1u

Picks Office
Last 30d: 86-71-2 (+11.3u)
LA -3-105
0.95u
X: PicksOffice

Cam Is Money
Last 30d: 71-88-2 (-8.3u)
J.Whittington o3.5 Recs-130
1u

DeadPresPicks
Last 30d: 12-23-0 (+2.8u)
T.Higbee First Touchdown Scorer Yes+1700
0.12u

💰🦡 Jake
Last 30d: 110-133-5 (+14.4u)
D.Adams 2+ TDs Yes+600
0.9u

Brandon Anderson
Last 30d: 52-99-0 (-3.1u)
LA -3-105
0.95u
Is this the best Sunday morning game of the season?
It might not have looked that way before the season, but this is suddenly a matchup of teams positioned to make the playoffs, with two of the more exciting offenses in football.
The Jaguars are back in London again, their home away from home. Jacksonville has played far more games in England than any other NFL team, and some may argue that gives the Jaguars something of a home field advantage.
Are we sure about that? Liam Coen is a first-year head coach and has the youngest, most inexperienced staff in the league, so this could be a big adjustment. Sean McVay has played out of the country before and should have his team ready, and he'll also be ready for Coen, a former longtime Rams assistant.
Usually in these neutral games, you just want the better team. And right now, the Rams are the better team.
The Rams enter the weekend fringe top five in my power ratings, while Jacksonville is still around league average.
The DVOA metrics back that up. The Rams rank top five by DVOA on both offense and defense, while the Jaguars are close to average at all three facets of the game.
Their offense has been fun but inconsistent, and the offensive line has faltered in recent weeks and could have its hands full with this young Rams defensive front. Trevor Lawrence has been sacked 10 times in just the last two weeks, a real red flag for a quarterback who usually doesn't struggle in that area.
The big name missing in this one is Puka Nacua.
Nacua has been the best receiver in the league this season, and he's a real loss to the Rams, but it matters that LA knew all week that it wouldn't have Nacua. McVay builds entire game plans around getting the ball to Nacua, so losing him midgame like last week can be a tough adjustment.
Now McVay has had an entire week to build a different game plan to face the Jaguars, a team that plays a ton of two-high safety — and that means that was probably always going to set up as a better game for field-stretchers like Davante Adams and Tyler Higbee.
Adams has been the clear No. 2 in Los Angeles with Nacua in the OPOY conversation, but this looks like it could be his breakout game in a Rams uniform, and I'm looking to invest heavily in Adams overs.
Just look at what opposing star WRs have done against Jacksonville this season. Ja'Marr Chase caught 14 balls for 165 yards and a score. Nico Collins had eight receptions for 104 and a TD. Last week, the Jaguars traded for CB Greg Newsome and he got torched by Jaxon Smith-Njigba for 162 yards and a touchdown on eight catches.
These receivers are much closer to Davante Adams in profile than Puka Nacua, not attacking underneath with YAC but beating the Jaguars over the top for big plays down the field.
But you won't have to tell Davante that. He had his best game since leaving Green Bay last season against these Jaguars: nine catches for 198 yards and a pair of touchdowns.
Could this be a huge game for Adams? He's always a touchdown threat in the red zone so play an Anytime Touchdown at +100 (bet365). Adams has a touchdown in half his Rams games already and in 14 of his last 27 games, over half. He has 24 career games with multiple scores, so place a portion of your TD wager on 2+ TDs at +650 (bet365).
Adams isn't always a huge yardage guy, but when he hits, he can put up some monster lines.
I'm forgoing his traditional yardage overs and playing some of the outliers in hope of a big game. A hundred receiving yards and a TD is +490 at bet365, a reasonable outcome for the top WR with Puka Nacua out.
Think he can match last year's performance or what Chase and JSN did to this defense? You can bet 150+ yards at +1000, or go for broke with a little nibble on 150 yards and a pair of TDs at +8150 (bet365).
I like the Anytime TD bet best along with the 100/1 bet, but I'm touching every one of those so split up your bet how you like.
The Rams have the better team, the more reliable offense, the better defense, and the best playmaker on the field in Davante Adams.
I like the Rams, even with Nacua out.
This line has sat right at Rams -3 all week long, the most important key number. There's still a chance it could move a touch toward Jacksonville before kickoff with Nacua out and the perceived home-field advantage if you want to risk it and wait for Rams -2.5, but it could go the other way and lose the key too.
I'll bet now at Rams -3 and live with the result — and hope for a huge Davante Adams day in blue and yellow.

Allan Lem
Last 30d: 139-99-6 (+16.1u)
T.Etienne u14.5 Rush Att+100
0.5u
Tailing @The_Oddsmaker

Sean Koerner
Last 30d: 50-37-0 (+7.7u)
T.Etienne u14.5 Rush Att+100
0.5u
Etienne is averaging 14.8 carries per game, but that’s been in near-perfect conditions. He’s been the clear lead back, the Jaguars have run the 7th-most plays per game, and they’ve only trailed 12% of the time (2nd lowest in the league).
This week they’re 3-point underdogs to the Rams. That doesn’t mean they can’t lead/win here and ETN clear this prop, but historically 3-point dogs trail at a +33% higher rate than he’s seen so far. That should lead to fewer rush attempts overall.
Rookie Bhayshul Tuten has been banged up but could start eating into ETN’s workload as he gets healthier. And in short yardage, ETN only has 38% of the team’s rush attempts.. Jacksonville has been pass-heavy on 2nd-and-short and often uses Lawrence or even WR runs instead of giving ETN as many of the cheap carries other lead backs get.
I project him closer to 13.8 carries with around a 60% chance to stay under 14.5.

Will Brinson
Last 30d: 31-29-1 (+0.2u)
LA -3-110
1u

Babs .
Last 30d: 96-101-3 (-2.1u)
LA -3-110
0.91u

Kendra Middleton
Last 30d: 15-8-0 (+8.2u)
T.Hunter Anytime TD Scorer Yes+305
3.05u

Invisible Insider
Last 30d: 11-12-0 (-1.4u)
JAC +3-110
1u

Brandon Anderson
Last 30d: 52-99-0 (-3.1u)
D.Adams Anytime TD Scorer Yes+100
1u
As discussed on Buckets, firing on a few Davante props with Puka out
D.Adams 2+ TDs Yes+650
1.63u
As discussed on Buckets, firing on a few Davante props with Puka out
D.Adams 150+ Receiving Yards Yes+1000
0.25u
As discussed on Buckets, firing on a few Davante props with Puka out

Action Pod NFL Picks
Last 30d: 67-118-0 (-1.9u)
LA -3-115
0.87u
@wheatonbrando https://myaction.app/bIlPMohsyXb

TAN Pod Touchdown Show
Last 30d: 14-49-1 (-4.4u)
J.Whittington Anytime TD Scorer Yes+275
0.5u
@ChrisRaybon https://myaction.app/MsfxZEmqyXb
H.Long Anytime TD Scorer Yes+400
0.5u
@ChrisRaybon https://myaction.app/MsfxZEmqyXb

Mjaybrod
Last 30d: 90-104-3 (-5.9u)
LA -3-110
0.91u
Super bowl contenders

Grant Neiffer
Last 30d: 32-88-0 (+1.3u)
K.Williams Anytime TD Scorer Yes-130
0.65u
Gilles Gallant
Last 30d: 26-87-1 (-17.2u)
T.Hunter Anytime TD Scorer Yes+310
1.55u

Boomer Betz
Last 30d: 174-163-3 (+11.9u)
JAC +3-101
1u

Royals Props
Last 30d: 33-21-1 (+7.4u)
J.Whittington o3.5 Recs-114
1.14u
FD🔨

Will Brinson
Last 30d: 31-29-1 (+0.2u)
D.Adams Anytime TD Scorer Yes+105
1u

Brandon Kravitz
Last 30d: 64-81-1 (-7.3u)
JAC +3-115
1.15u

FTN Fantasy
Last 30d: 52-44-1 (+11.0u)
LA -3.5+112
2.24u

Boomer Betz
Last 30d: 174-163-3 (+11.9u)
K.Williams u17.5 Rec Yds-115
0.87u

Cam Is Money
Last 30d: 71-88-2 (-8.3u)
T.Higbee Anytime TD Scorer Yes+280
0.4u

💰🦡 Jake
Last 30d: 110-133-5 (+14.4u)
D.Adams 2+ TDs Yes+650
0.65u
D.Adams Anytime TD Scorer Yes+105
0.11u
LA -2.5-120
1u

Chris Gimino
Last 30d: 32-41-1 (-5.6u)
Under 44.5-104
0.96u
JAC +130
1u

FTN Fantasy
Last 30d: 52-44-1 (+11.0u)
JAC +3-105
1u
Rams vs. Jaguars Previews & Analysis
Rams vs. Jaguars Props
Prop Projections
There are no prop projections found for the selected slate. Please check back later.
Prop Odds Comparison
Line Movement Tracker
Rams vs. Jaguars Public Betting Percentages
Betting Trends
- Jaguars are 3-2 in their last 5 games.
- Jaguars are 3-2 in their last 5 games against the spread
- Jaguars are 1-1 in their road games against the spread
- The totals have gone OVER in 1 of Jaguars' last 5 games
- The totals have gone OVER in 1 of Jaguars' 4 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Rams vs. Jaguars Injury Updates

Rams Injuries
- Puka NacuaWR
Nacua is out with ankle
Out

Jaguars Injuries
- Cole Van LanenOL
Van Lanen is questionable with shoulder
Questionable
- Brenton StrangeTE
Strange is out with hip
Out
- Wyatt MilumOL
Milum is out with knee
Out
Team Stats
Rams vs. Jaguars Odds Comparison
Could not load odds
Rams at Jaguars Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Rams 5-2 | o23.5-117 | u23.5-106 |
![]() Jaguars 4-3 | o20.5-107 | u20.5-115 |