Rams vs. Jaguars Odds & Betting Predictions - October 19, 2025

Rams at Jaguars

1:30 pm • NFL Network
35 - 7

Rams at Jaguars Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Rams
5-2
-3.5
-3-115
o44.5-105
-166
Jaguars
4-3
u47.5
+3-105
u44.5-115
+142
location pinSunday 1:30 p.m.
October 19, 2025
Wembley StadiumLondon
Rams vs. Jaguars Expert Picks
Moneyline Hacks
Moneyline Hacks
Last 30d: 110-112-3 (+47.6u)
D.Adams 25+ Receiving Yards Yes (Live)+1450
21.75u
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B.Thomas 25+ Receiving Yards Yes (Live)-1250
0.12u
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Greg Matherne
Greg Matherne
Last 30d: 36-49-2 (+0.3u)
Under 44.5-110
0.5u
PvB Bets
PvB Bets
Last 30d: 7-1-0 (+5.0u)
J.Whittington o3.5 Recs-114
1u
Jordan Whittington ⬆️ 3.5 Receptions (-114 @ FanDuel)(LAR) With Puka Nacua sidelined due to an ankle injury, Whittington is poised to step into an expanded role within the Rams' passing game. His snap count has already been trending upward, and without Nacua, he's set for his highest usage of the season. He's demonstrated his capability with 2+ receptions in four of his last five games, and last week, he saw four targets even in a relatively low-scoring game against a depleted Ravens team. The upcoming matchup against the Jacksonville Jaguars is also a plus spot for Jordan. Jacksonville utilizes zone coverage at one of the highest rates in the league (79.7%). Here is hoe Whittington has done against zone and man: **Vs Zone: 7.6% target rate, 80.0% catch rate and 8.6% 1st read rate** Vs Man: 4.5 % target rate, 66.7% catch rate and 3.6% 1st read rate Furthermore, the Jaguars' have a good run defense, which ranks 12th in the league and hasn't allowed any opposing running back over 60 rushing yards this season, which will likely force the Rams to lean heavily on their passing game. This looks like a great spot for Whittington to step up in Nacua's absence.
Sir Lockselot
Sir Lockselot
Last 30d: 31-61-0 (-17.2u)
JAC +140
2u
📚Player Profit 🔑 Jaguars ML +140 (Player Profit) 2u Jags are London’s team. Getting to face a banged up Rams team without Puka. Love this spot for Jacksonville to get it done.
Picks Office
Picks Office
Last 30d: 86-71-2 (+11.3u)
Under 44.5-105
0.95u
Sandy Plashkes
Sandy Plashkes
Last 30d: 99-101-2 (+13.1u)
T.Hunter o41.5 Rec Yds-112
1u
Picks Office
Picks Office
Last 30d: 86-71-2 (+11.3u)
LA -3-105
0.95u
X: PicksOffice
Cam Is Money
Cam Is Money
Last 30d: 71-88-2 (-8.3u)
J.Whittington o3.5 Recs-130
1u
DeadPresPicks
DeadPresPicks
Last 30d: 12-23-0 (+2.8u)
T.Higbee First Touchdown Scorer Yes+1700
0.12u
💰🦡 Jake
💰🦡 Jake
Last 30d: 110-133-5 (+14.4u)
D.Adams 2+ TDs Yes+600
0.9u
Brandon Anderson
Brandon Anderson
Last 30d: 52-99-0 (-3.1u)
LA -3-105
0.95u
Is this the best Sunday morning game of the season? It might not have looked that way before the season, but this is suddenly a matchup of teams positioned to make the playoffs, with two of the more exciting offenses in football. The Jaguars are back in London again, their home away from home. Jacksonville has played far more games in England than any other NFL team, and some may argue that gives the Jaguars something of a home field advantage. Are we sure about that? Liam Coen is a first-year head coach and has the youngest, most inexperienced staff in the league, so this could be a big adjustment. Sean McVay has played out of the country before and should have his team ready, and he'll also be ready for Coen, a former longtime Rams assistant. Usually in these neutral games, you just want the better team. And right now, the Rams are the better team. The Rams enter the weekend fringe top five in my power ratings, while Jacksonville is still around league average. The DVOA metrics back that up. The Rams rank top five by DVOA on both offense and defense, while the Jaguars are close to average at all three facets of the game. Their offense has been fun but inconsistent, and the offensive line has faltered in recent weeks and could have its hands full with this young Rams defensive front. Trevor Lawrence has been sacked 10 times in just the last two weeks, a real red flag for a quarterback who usually doesn't struggle in that area. The big name missing in this one is Puka Nacua. Nacua has been the best receiver in the league this season, and he's a real loss to the Rams, but it matters that LA knew all week that it wouldn't have Nacua. McVay builds entire game plans around getting the ball to Nacua, so losing him midgame like last week can be a tough adjustment. Now McVay has had an entire week to build a different game plan to face the Jaguars, a team that plays a ton of two-high safety — and that means that was probably always going to set up as a better game for field-stretchers like Davante Adams and Tyler Higbee. Adams has been the clear No. 2 in Los Angeles with Nacua in the OPOY conversation, but this looks like it could be his breakout game in a Rams uniform, and I'm looking to invest heavily in Adams overs. Just look at what opposing star WRs have done against Jacksonville this season. Ja'Marr Chase caught 14 balls for 165 yards and a score. Nico Collins had eight receptions for 104 and a TD. Last week, the Jaguars traded for CB Greg Newsome and he got torched by Jaxon Smith-Njigba for 162 yards and a touchdown on eight catches. These receivers are much closer to Davante Adams in profile than Puka Nacua, not attacking underneath with YAC but beating the Jaguars over the top for big plays down the field. But you won't have to tell Davante that. He had his best game since leaving Green Bay last season against these Jaguars: nine catches for 198 yards and a pair of touchdowns. Could this be a huge game for Adams? He's always a touchdown threat in the red zone so play an Anytime Touchdown at +100 (bet365). Adams has a touchdown in half his Rams games already and in 14 of his last 27 games, over half. He has 24 career games with multiple scores, so place a portion of your TD wager on 2+ TDs at +650 (bet365). Adams isn't always a huge yardage guy, but when he hits, he can put up some monster lines. I'm forgoing his traditional yardage overs and playing some of the outliers in hope of a big game. A hundred receiving yards and a TD is +490 at bet365, a reasonable outcome for the top WR with Puka Nacua out. Think he can match last year's performance or what Chase and JSN did to this defense? You can bet 150+ yards at +1000, or go for broke with a little nibble on 150 yards and a pair of TDs at +8150 (bet365). I like the Anytime TD bet best along with the 100/1 bet, but I'm touching every one of those so split up your bet how you like. The Rams have the better team, the more reliable offense, the better defense, and the best playmaker on the field in Davante Adams. I like the Rams, even with Nacua out. This line has sat right at Rams -3 all week long, the most important key number. There's still a chance it could move a touch toward Jacksonville before kickoff with Nacua out and the perceived home-field advantage if you want to risk it and wait for Rams -2.5, but it could go the other way and lose the key too. I'll bet now at Rams -3 and live with the result — and hope for a huge Davante Adams day in blue and yellow.
Allan Lem
Allan Lem
Last 30d: 139-99-6 (+16.1u)
T.Etienne u14.5 Rush Att+100
0.5u
Tailing @The_Oddsmaker
Sean Koerner
Sean Koerner
Last 30d: 50-37-0 (+7.7u)
T.Etienne u14.5 Rush Att+100
0.5u
Etienne is averaging 14.8 carries per game, but that’s been in near-perfect conditions. He’s been the clear lead back, the Jaguars have run the 7th-most plays per game, and they’ve only trailed 12% of the time (2nd lowest in the league). This week they’re 3-point underdogs to the Rams. That doesn’t mean they can’t lead/win here and ETN clear this prop, but historically 3-point dogs trail at a +33% higher rate than he’s seen so far. That should lead to fewer rush attempts overall. Rookie Bhayshul Tuten has been banged up but could start eating into ETN’s workload as he gets healthier. And in short yardage, ETN only has 38% of the team’s rush attempts.. Jacksonville has been pass-heavy on 2nd-and-short and often uses Lawrence or even WR runs instead of giving ETN as many of the cheap carries other lead backs get. I project him closer to 13.8 carries with around a 60% chance to stay under 14.5.
Will Brinson
Will Brinson
Last 30d: 31-29-1 (+0.2u)
LA -3-110
1u
Babs .
Babs .
Last 30d: 96-101-3 (-2.1u)
LA -3-110
0.91u
Kendra Middleton
Kendra Middleton
Last 30d: 15-8-0 (+8.2u)
T.Hunter Anytime TD Scorer Yes+305
3.05u
Invisible Insider
Invisible Insider
Last 30d: 11-12-0 (-1.4u)
JAC +3-110
1u
Brandon Anderson
Brandon Anderson
Last 30d: 52-99-0 (-3.1u)
D.Adams Anytime TD Scorer Yes+100
1u
As discussed on Buckets, firing on a few Davante props with Puka out
D.Adams 2+ TDs Yes+650
1.63u
As discussed on Buckets, firing on a few Davante props with Puka out
D.Adams 150+ Receiving Yards Yes+1000
0.25u
As discussed on Buckets, firing on a few Davante props with Puka out
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 67-118-0 (-1.9u)
LA -3-115
0.87u
TAN Pod Touchdown Show
TAN Pod Touchdown Show
Last 30d: 14-49-1 (-4.4u)
J.Whittington Anytime TD Scorer Yes+275
0.5u
H.Long Anytime TD Scorer Yes+400
0.5u
Mjaybrod
Mjaybrod
Last 30d: 90-104-3 (-5.9u)
LA -3-110
0.91u
Super bowl contenders
Grant Neiffer
Grant Neiffer
Last 30d: 32-88-0 (+1.3u)
K.Williams Anytime TD Scorer Yes-130
0.65u
Gilles Gallant
Gilles Gallant
Last 30d: 26-87-1 (-17.2u)
T.Hunter Anytime TD Scorer Yes+310
1.55u
Boomer Betz
Boomer Betz
Last 30d: 174-163-3 (+11.9u)
JAC +3-101
1u
Royals Props
Royals Props
Last 30d: 33-21-1 (+7.4u)
J.Whittington o3.5 Recs-114
1.14u
FD🔨
Will Brinson
Will Brinson
Last 30d: 31-29-1 (+0.2u)
D.Adams Anytime TD Scorer Yes+105
1u
Brandon Kravitz
Brandon Kravitz
Last 30d: 64-81-1 (-7.3u)
JAC +3-115
1.15u
FTN Fantasy
FTN Fantasy
Last 30d: 52-44-1 (+11.0u)
LA -3.5+112
2.24u
Boomer Betz
Boomer Betz
Last 30d: 174-163-3 (+11.9u)
K.Williams u17.5 Rec Yds-115
0.87u
Cam Is Money
Cam Is Money
Last 30d: 71-88-2 (-8.3u)
T.Higbee Anytime TD Scorer Yes+280
0.4u
💰🦡 Jake
💰🦡 Jake
Last 30d: 110-133-5 (+14.4u)
D.Adams 2+ TDs Yes+650
0.65u
D.Adams Anytime TD Scorer Yes+105
0.11u
LA -2.5-120
1u
Chris Gimino
Chris Gimino
Last 30d: 32-41-1 (-5.6u)
Under 44.5-104
0.96u
JAC +130
1u
FTN Fantasy
FTN Fantasy
Last 30d: 52-44-1 (+11.0u)
JAC +3-105
1u

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Rams vs. Jaguars Props

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Line Movement Tracker

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Rams vs. Jaguars Public Betting Percentages

Away Logo

Rams

Public

37%

Bets%

63%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Jaguars
4-33-11-12-02-3
Rams
5-22-12-15-10-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Jaguars
3-41-32-00-23-2
Rams
3-41-22-12-41-0

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Jaguars
4-3N/AN/A2-02-3
Rams
5-2N/AN/A5-10-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 12thSEAL 12-20+1.5 LU 47.5SEA -105
Oct 7thKCW 31-28+3.5 WO 45.5JAC +165
Sep 28th@SFW 26-21+3.5 WO 45.5JAC +144
Sep 21stHOUW 17-10-1.5 WU 42.5JAC -120
Sep 14th@CINL 27-31+3.5 LO 49.5CIN +155

Rams vs. Jaguars Injury Updates

Rams Injuries

  • Puka Nacua
    WR

    Nacua is out with ankle

    Out

Jaguars Injuries

  • Cole Van Lanen
    OL

    Van Lanen is questionable with shoulder

    Questionable

  • Brenton Strange
    TE

    Strange is out with hip

    Out

  • Wyatt Milum
    OL

    Milum is out with knee

    Out

Team Stats
271
Total Yards
358
62
Total Plays
74
4.4
Yards Per Play
4.8
182
YDS
296
21/33
Comps/Atts
23/48
5.515
YPA
4.8
5/0
TDs/INTs
1/0
0/0
Sacks/Yards
7/32
89
Rush Yards
94
29
Attempts
19
3.069
YPC
4.947
0
TDs
0

Turnovers

0
Fumbles Lost
0
0
Interceptions
0

Efficiency

4/4 100%
Redzone
0/2 0%
2/10 0%
3rd Down
3/15 0%
2/2 0%
4th Down
2/6 0%

First Downs

26
Total
21
14
Pass
13
4
Rush
5
8
Penalty
3
5/45
Penalties/Yards
13/119
31:46
Possession
28:14

Rams vs. Jaguars Odds Comparison

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Rams at Jaguars Team Totals

MatchupOverUnder
Rams
5-2
o23.5-117
u23.5-106
Jaguars
4-3
o20.5-107
u20.5-115