| Steve Mounie | F | Out | Heel Injury | Heel Injury | Nov 6 |
| Niklas Lomb | GK | Out indefinitely | Virus | Virus | Jan 24 |
| Jonas Omlin | GK | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Mar 18 |
| Loic Bade | DEF | Out indefinitely | Hamstring | Hamstring | Feb 25 |
| Manuel Neuer | GK | Out indefinitely | Broken Leg | Broken Leg | Apr 11 |
| Raphael Guerreiro | DEF | Out indefinitely | Knock | Knock | Nov 5 |
| Jamal Musiala | MID | Out indefinitely | Hamstring | Hamstring | Apr 3 |
| David Santos Daiber | MID | Out | David Santos Daiber is expected to return Late April 2026 from Thigh injury. | Daiber is out with thigh | Apr 1 |
| Emre Can | MID | Out indefinitely | MCL Knee Ligament Injury | MCL Knee Ligament Injury | Feb 14 |
| Karim Adeyemi | MID | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Apr 3 |
| Fabio Silva | F | Out | Fábio Silva is expected to return Mid September 2025 from Knock injury. | Silva is out with maintenance | Aug 26 |
| Franck Honorat | MID | Doubtful | None | Honorat is doubtful | Jul 12 |
| Hugo Bolin | MID | Doubtful | Hugo Bolin is Doubtful with Ankle injury. | Bolin is doubtful with ankle | Dec 6 |
| L. Klünter | DEF | Out indefinitely | Shoulder Injury | Shoulder Injury | May 2 |
| S. Kapino | GK | Out | Hip/Thigh Injury | Hip/Thigh Injury | Feb 8 |
| N. De Medina | DEF | Out indefinitely | Illness | Illness | Feb 7 |
| J. Laursen | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Mar 19 |
| S. Vasiliadis | MID | Out indefinitely | Knee Injury | Knee Injury | Apr 18 |
| B. Lasme | A | Out indefinitely | Knee Injury | Knee Injury | Jul 11 |
| F. Krüger | A | Out indefinitely | Illness | Illness | Dec 6 |
| Michy Batshuayi | F | Out indefinitely | Hamstring | Hamstring | Nov 23 |
| Michael Zetterer | GK | Out | Arm/Elbow injury | Arm/Elbow injury | Apr 4 |
| Rasmus Kristensen | DEF | Out | Rasmus Kristensen is expected to return Mid April 2026 from Ankle injury. | Kristensen is out with ankle | Apr 1 |
| Jonathan Burkardt | F | Out | Jonathan Burkardt is expected to return Late February 2026 from Calf injury. | Burkardt is out with calf | Feb 12 |
| Paulo Otávio | DEF | Out indefinitely | Knee Injury | Knee Injury | Aug 8 |
| Andreas Poulsen | DEF | Out | Shoulder Injury | Shoulder Injury | Oct 31 |
| Danny Blum | A | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Apr 11 |
| J. Horn | DEF | Out indefinitely | Hip/Thigh Injury | Hip/Thigh Injury | Sep 5 |
| C. Schindler | DEF | Out | Illness | Illness | Mar 30 |
| L. Tempelmann | MID | Out indefinitely | Ankle Ligaments | Ankle Ligaments | Apr 4 |
| F. Hübner | DEF | Out indefinitely | Knock | Knock | Nov 4 |
| T. Usami | MID | Out | Knee Injury | Knee Injury | Apr 25 |
| A. Morales | MID | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | May 18 |
| Thomas Pledl | MID | Out indefinitely | ACL Knee Ligament Injury | ACL Knee Ligament Injury | Dec 15 |
| Leonardo Pablo Koutris | DEF | Out | ACL Knee Ligament Injury | ACL Knee Ligament Injury | Oct 27 |
| F. Klaus | MID | Out | Suspended | Suspended | May 30 |
| Daniel Ginczek | A | Out indefinitely | Virus | Virus | Jan 24 |
| Benito Raman | A | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | May 8 |
| Róbert Boženík | A | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Jan 25 |
| M. Christiansen | MID | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | May 9 |
| J. Willems | DEF | Out | ACL Knee Ligament Injury | ACL Knee Ligament Injury | Dec 16 |
| J. Hoogma | DEF | Out indefinitely | Virus | Virus | Jan 24 |
| R. Ache | A | Out indefinitely | Thigh Muscle Rupture | Thigh Muscle Rupture | Feb 26 |
| Yussuf Poulsen | F | Out indefinitely | Illness | Illness | Oct 5 |
| Philipas Otele | F | Out indefinitely | Philip Otele is Unknown with Lack of fitness. | Otele is injured with conditioning | Jan 19 |
| Håvard Kallevik Nielsen | A | Out indefinitely | Knock | Knock | Jul 4 |
| Nicolai Müller | MID | Out indefinitely | Knee Injury | Knee Injury | Oct 14 |
| Pirmin Schwegler | MID | Out | Hip/Thigh Injury | Hip/Thigh Injury | Mar 29 |
| D. Aogo | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Apr 13 |
| P. Twumasi | A | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Oct 7 |
| Josip Elez | DEF | Out | Knock | Knock | Mar 17 |
| Jonathas | A | Out | Suspended | Suspended | May 11 |
| Salif Sané | DEF | Out | Suspended | Suspended | May 8 |
| Florian Niederlechner | F | Out indefinitely | Knock | Knock | Jan 30 |
| Filip Uremovic | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Oct 29 |
| Wilfried Kanga | F | Out indefinitely | Toe Injury | Toe Injury | Mar 13 |
| Deyovaisio Zeefuik | DEF | Out indefinitely | Groin Strain | Groin Strain | Oct 25 |
| Agustin Rogel | DEF | Out indefinitely | Knee Injury | Knee Injury | Feb 20 |
| Anthony Caci | DEF | Out | Gluteal Strain | Gluteal Strain | Feb 29 |
| Niklas Tauer | MID | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Feb 6 |
| M. Terrazzino | A | Out | MCL Knee Ligament Injury | MCL Knee Ligament Injury | Oct 4 |
| C. Okoroji | DEF | Out indefinitely | Thigh Muscle Rupture | Thigh Muscle Rupture | Jun 17 |
| M. Ritter | A | Out | Back Injury | Back Injury | Nov 30 |
| S. Mamba | A | Out | Suspended | Suspended | Jun 13 |
| Paul Seguin | MID | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | May 9 |
| Timo Baumgartl | DEF | Out indefinitely | Testicular Cancer | Testicular Cancer | Sep 8 |
| Thomas Ouwejan | DEF | Out indefinitely | Groin Strain | Groin Strain | Mar 13 |
| Ibrahima Cisse | DEF | Out indefinitely | Knock | Knock | Feb 6 |
| Leo Greiml | DEF | Out indefinitely | Knock | Knock | Jan 23 |
| Oliver Burke | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Jun 7 |
| Danilho Doekhi | DEF | Out indefinitely | None | Doekhi is injured | Oct 27 |
| Alex Kral | MID | Out indefinitely | Back Injury | Back Injury | Jan 30 |
| Andras Schafer | MID | Out indefinitely | Foot Injury | Foot Injury | Apr 11 |
| Christian Eriksen | MID | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Feb 25 |
| Kevin Paredes | MID | Out indefinitely | Calf/Shin Injury | Calf/Shin Injury | Jan 23 |
| Moritz Jenz | DEF | Out indefinitely | Knock | Knock | Apr 11 |
FC Ingolstadt 04
FC Nürnberg
Fortuna Düsseldorf
Greuther Furth
Hannover 96
Hertha BSC
SC Paderborn 07
Schalke 04
