| Fernand Mayembo | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Feb 20 |
| Riad Nouri | F | Out indefinitely | Knock | Knock | Feb 27 |
| Alaeddine Yahia | DEF | Out indefinitely | Hip/Thigh Injury | Hip/Thigh Injury | Jun 12 |
| Geoffrey Jourdren | GK | Out indefinitely | Knee Injury | Knee Injury | Apr 14 |
| N. Saint-Ruf | DEF | Out | Suspended | Suspended | Apr 9 |
| Tobias Badila Kouendolo | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Apr 23 |
| Michaël Chrétien Basser | DEF | Out indefinitely | Knock | Knock | Mar 6 |
| Issiar Dia | MID | Out indefinitely | Hip/Thigh Injury | Hip/Thigh Injury | Jun 12 |
| Vincent Muratori | DEF | Out | MCL Knee Ligament Injury | MCL Knee Ligament Injury | Jun 12 |
| Alou Diarra | MID | Out indefinitely | Knee Injury | Knee Injury | Jun 12 |
| Serge Yao N'Guessan | MID | Out indefinitely | Knee Injury | Knee Injury | Apr 23 |
| Benoît Pedretti | MID | Out indefinitely | Calf/Shin Injury | Calf/Shin Injury | Jun 12 |
| A. Koura | A | Out indefinitely | Knock | Knock | May 15 |
| Christophe Mandanne | A | Out indefinitely | Illness | Illness | Mar 13 |
| A. Diakhaby | A | Out | Hamstring | Hamstring | Apr 26 |
| Serge Gakpé | A | Out indefinitely | Head Injury | Head Injury | May 14 |
| B. Dibassy | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Mar 24 |
| S. Koita | A | Out indefinitely | Knock | Knock | Feb 12 |
| George Gope-Fenepej | A | Out indefinitely | Knock | Knock | May 21 |
| C. Akolo | MID | Out | Knock | Knock | Jan 25 |
| B. Zungu | MID | Out | Suspended | Suspended | Mar 15 |
| R. Coly | DEF | Out indefinitely | Neck Injury | Neck Injury | Jan 7 |
| Rafał Maciej Kurzawa | MID | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Dec 24 |
| Mamadou Fofana I | MID | Out | Virus | Virus | Oct 26 |
| Jim Allevinah | F | Out | Jim Allevinah is expected to return Late November 2025 from Calf injury. | Allevinah is out with calf | Sep 25 |
| Gideon Mensah | DEF | Out indefinitely | Knee Injury | Knee Injury | Apr 11 |
| Sinaly Diomande | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Aug 2 |
| Telli Siwe | DEF | Out | Telli Siwe is expected to return Early November 2025 from Sprained knee injury. | Siwe is out with knee | Oct 2 |
| Lucas Tousart | MID | Out | Tousart, Lucas: missing - other | Tousart is out | Aug 23 |
| Eric Ebimbe | MID | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Mar 21 |
| Julien Le Cardinal | DEF | Doubtful | None | Le Cardinal is doubtful | May 16 |
| Damien Da Silva | DEF | Out indefinitely | Back Injury | Back Injury | Nov 29 |
| Elbasan Rashani | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Apr 3 |
| Neto Borges | DEF | Out | Knee Injury | Knee Injury | Nov 14 |
| Yoel Armougom | DEF | Out indefinitely | Yoel Armougom is Unknown with Muscle injury. | Armougom is injured with muscle | Sep 12 |
| Bobby Allain | GK | Out indefinitely | Overtired | Overtired | Jan 10 |
| Arnold Bouka Moutou | DEF | Out | Calf Muscle Strain | Calf Muscle Strain | Mar 30 |
| B. Reynet | GK | Out indefinitely | Hip/Thigh Injury | Hip/Thigh Injury | Mar 8 |
| Cédric Varrault | DEF | Out | Groin/Pelvis Injury | Groin/Pelvis Injury | May 14 |
| Florent Balmont | MID | Out indefinitely | Groin/Pelvis Injury | Groin/Pelvis Injury | May 13 |
| R. Amalfitano | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | Oct 25 |
| Anthony Belmonte | MID | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Aug 19 |
| Jordan Marié | MID | Out | Illness | Illness | Nov 19 |
| Marvin Martin | MID | Out indefinitely | Groin/Pelvis Injury | Groin/Pelvis Injury | Jan 20 |
| Frédéric Sammaritano | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | May 24 |
| Guillaume Sarrabayrouse | MID | Out indefinitely | Knock | Knock | Mar 20 |
| Júlio Tavares | A | Out indefinitely | Groin Strain | Groin Strain | Sep 27 |
| L. Deaux | MID | Out | Groin Strain | Groin Strain | May 30 |
| Y. Benzia | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | May 24 |
| Romain Philippoteaux | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | May 30 |
| B. Jeannot | A | Out indefinitely | Hip/Thigh Injury | Hip/Thigh Injury | May 19 |
| D. Congré | DEF | Out | Suspended | Suspended | Dec 4 |
| M. Le Bihan | A | Out indefinitely | Knee Injury | Knee Injury | Apr 10 |
| Y. Gourcuff | MID | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Jan 27 |
| Cédric Yamberé | DEF | Out | Suspended | Suspended | Oct 21 |
| A. Chalá | DEF | Out | Calf Muscle Strain | Calf Muscle Strain | May 29 |
| C. Traoré | DEF | Out | Virus | Virus | Apr 29 |
| C. Rocchia | DEF | Out | Medical Condition | Medical Condition | May 4 |
| P. Joly | DEF | Out indefinitely | Ankle Ligaments | Ankle Ligaments | Jan 30 |
| Papiss Mison Djilobodji | DEF | Out indefinitely | Knock | Knock | May 30 |
| Vincent Manceau | DEF | Out | Groin Strain | Groin Strain | Apr 25 |
| R. Rodelin | A | Out indefinitely | Knock | Knock | May 30 |
| Christophe Kerbrat | DEF | Out indefinitely | Knock | Knock | May 30 |
| Dorian Lévêque | DEF | Out indefinitely | Concussion | Concussion | May 15 |
| Reynald Lemaître | DEF | Out indefinitely | Knock | Knock | Mar 16 |
| Jeremy Sorbon | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Mar 19 |
| Etienne Didot | MID | Out | Knee Injury | Knee Injury | Feb 17 |
| Jimmy Briand | A | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Apr 18 |
| Sloan Privat | A | Out indefinitely | Groin Strain | Groin Strain | Jan 12 |
| M. Barthelmé | MID | Out indefinitely | Groin/Pelvis Injury | Groin/Pelvis Injury | Apr 10 |
| M. Poaty | DEF | Out indefinitely | Knee Injury | Knee Injury | Sep 17 |
| Mathieu Bodmer | DEF | Out | Calf Muscle Strain | Calf Muscle Strain | Mar 14 |
| A. Romao | MID | Out indefinitely | Inguinal Hernia | Inguinal Hernia | Jan 9 |
| Felix Eboa Eboa | MID | Out | Knock | Knock | Nov 29 |
| Abdoul Razzagui Camara | A | Out indefinitely | LCL Knee Ligament Injury | LCL Knee Ligament Injury | Aug 26 |
| B. Pelé | MID | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Dec 4 |
| W. Tchimbembé | MID | Out | Knee Injury | Knee Injury | Aug 23 |
| Ante Palaversa | MID | Out | Knee Injury | Knee Injury | Mar 6 |
| Abdu Conte | DEF | Out indefinitely | Knock | Knock | Apr 11 |
| Thierno Balde | DEF | Out indefinitely | Knock | Knock | Mar 6 |
| Andreas Bruus | DEF | Out | Groin/Pelvis Injury | Groin/Pelvis Injury | Feb 24 |
| Jérôme Prior | GK | Out indefinitely | Knock | Knock | Dec 3 |
| Maxime Poundjé | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Jan 18 |
| Jaroslav Plasil | MID | Out | Suspended | Suspended | Jan 28 |
| Jérémy Toulalan | MID | Out indefinitely | Groin/Pelvis Injury | Groin/Pelvis Injury | Mar 20 |
| Abdou Traoré | MID | Out indefinitely | Knock | Knock | Mar 3 |
| F. Kamano | A | Out indefinitely | Foot Injury | Foot Injury | Feb 2 |
| A. Mendy | A | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Nov 21 |
| Y. Sankharé | MID | Out | Suspended | Suspended | Dec 29 |
| N. de Préville | A | Out | Suspended | Suspended | May 20 |
| Mexer | DEF | Out indefinitely | Virus | Virus | Jan 8 |
| V. Jovanović | DEF | Out indefinitely | Knock | Knock | Jan 25 |
| Jonathan Cafú | A | Out indefinitely | Illness | Illness | Jun 11 |
| Marcelo | DEF | Out | Groin/Pelvis Injury | Groin/Pelvis Injury | Apr 24 |
| S. Kalu | A | Out | Ankle/Foot Injury | Ankle/Foot Injury | Apr 23 |
| A. Medioub | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | May 2 |
| Thomas Delaine | DEF | Out | Thomas Delaine is expected to return in About 1-2 weeks from Muscle injury. | Delaine is out with muscle | Oct 5 |
| Florian Thauvin | F | Out indefinitely | Knee Injury | Knee Injury | Mar 1 |
| Odsonne Edouard | F | Doubtful | Odsonne Edouard is Doubtful with Hamstring Injury. | Edouard is doubtful with hamstring | Oct 7 |
| Deiver Machado | DEF | Out | Deiver Machado is expected to return Late October 2025 from Knee injury. | Machado is out with knee | Oct 11 |
| Facundo Medina | DEF | Out | Facundo Medina is expected to return Late November 2025 from Sprained ankle. | Medina is out with ankle | Oct 1 |
| Abdallah Sima | F | Out indefinitely | Knock | Knock | Feb 2 |
| Benjamin Leroy | GK | Out indefinitely | Head Injury | Head Injury | Oct 10 |
| Yvon Mvogo | GK | Out | Thigh Muscle Strain | Thigh Muscle Strain | Apr 11 |
| Bingourou Kamara | GK | Out | Knee Injury | Knee Injury | Jan 19 |
| Igor Silva | DEF | Out | Suspended | Suspended | Apr 2 |
| Panos Katseris | MID | Out | Panos Katseris is expected to return Late October 2025 from Hamstring Injury. | Katseris is out with hamstring | Oct 10 |
| Nathaniel Adjei | DEF | Out | Nathaniel Adjei is expected to return Late October 2025 from Ankle injury. | Adjei is out with ankle | Oct 11 |
| Amine Harit | MID | Out indefinitely | None | Harit is injured | Jul 22 |
| Geoffrey Kondogbia | MID | Out indefinitely | Knock | Knock | Mar 6 |
| Ruben Blanco | GK | Out indefinitely | Illness | Illness | May 9 |
| Geronimo Rulli | GK | Out | Suspended | Suspended | May 16 |
| Leonardo Balerdi | DEF | Out | Suspended | Suspended | Mar 31 |
| Hamed Junior Traore | MID | Out | None | Traore is out | Jul 1 |
| Amine Gouiri | F | Out | Amine Gouiri is expected to return in About 1-2 weeks from Shoulder injury. | Gouiri is out with shoulder | Oct 14 |
| Benjamin Stambouli | DEF | Out | Benjamin Stambouli is expected to return Late October 2025 from Knee injury. | Stambouli is out with knee | Oct 2 |
| Paul Pogba | MID | Out indefinitely | Calf/Shin Injury | Calf/Shin Injury | Dec 7 |
| Eric Dier | DEF | Out | Thigh Muscle Rupture | Thigh Muscle Rupture | Feb 19 |
| Lukas Hradecky | GK | Out | Achilles tendonitis | Achilles tendonitis | Apr 3 |
| Thilo Kehrer | DEF | Out indefinitely | Virus | Virus | Jan 10 |
| Caio Henrique | DEF | Out indefinitely | Illness | Illness | Aug 12 |
| Takumi Minamino | MID | Out indefinitely | Overtired | Overtired | Aug 12 |
| Aleksandr Golovin | MID | Doubtful | Aleksandr Golovin is Doubtful with Thigh injury. | Golovin is doubtful with thigh | Oct 14 |
| Vanderson | DEF | Out | Vanderson is expected to return Late October 2025 from Hamstring Injury. | Vanderson is out with hamstring | Oct 2 |
| Ansu Fati | F | Out indefinitely | Knee Injury | Knee Injury | Mar 6 |
| Christian Mawissa | DEF | Out | Christian Mawissa is expected to return Late October 2025 from Hamstring Injury. | Mawissa is out with hamstring | Oct 3 |
| Lamine Camara | MID | Out | Lamine Camara is expected to return Late November 2025 from Ankle injury. | Camara is out with ankle | Sep 29 |
| Stanis Idumbo-Muzambo | MID | Out indefinitely | Idumbo-Muzambo, Stanis: missing - injured | Idumbo-Muzambo is injured | Aug 22 |
| Aladji Bamba | MID | Doubtful | Aladji Bamba is Doubtful with Hamstring Injury. | Bamba is doubtful with hamstring | Oct 14 |
| Tanguy Coulibaly | MID | Out indefinitely | Knock | Knock | Nov 11 |
| Francis Coquelin | MID | Out indefinitely | MCL Knee Ligament Injury | MCL Knee Ligament Injury | Apr 11 |
| Fabien Centonze | DEF | Out indefinitely | Centonze, Fabien: missing - injured | Centonze is injured | Aug 23 |
| Ignatius Ganago | F | Out | Ignatius Ganago is expected to return Late October 2025 from Calf injury. | Ganago is out with calf | Oct 11 |
| Mostafa Mohamed | F | Out indefinitely | Ankle Ligaments | Ankle Ligaments | May 11 |
| Johann Lepenant | MID | Out | Johann Lepenant is expected to return Mid November 2025 from Shin injury. | Lepenant is out with shin | Oct 15 |
| Nicolas Cozza | DEF | Out indefinitely | None | Cozza is injured | Sep 14 |
| Tylel Tati | DEF | Out | Tylel Tati is expected to return Late October 2025 from Groin injury. | Tati is out with groin | Oct 3 |
| P. Martinez | DEF | Out | Back Injury | Back Injury | Jun 14 |
| Patrick Burner | DEF | Out | Virus | Virus | Apr 29 |
| N. Roux | A | Out | Unknown | Unknown | Feb 25 |
| L. Landre | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Feb 25 |
| B. Poulain | DEF | Out | Suspended | Suspended | Apr 23 |
| S. Ben Amar | A | Out indefinitely | Knee Injury | Knee Injury | Mar 8 |
| S. Sarr | | Out | Calf Muscle Strain | Calf Muscle Strain | Apr 14 |
| Z. Ferhat | MID | Out | Groin/Pelvis Injury | Groin/Pelvis Injury | May 30 |
| L. Fomba | MID | Out indefinitely | Hip/Thigh Injury | Hip/Thigh Injury | Jan 6 |
| Y. Benrahou | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | May 30 |
| K. Aribi | A | Out | Ankle Ligaments | Ankle Ligaments | Apr 4 |
| Hamari Traore | DEF | Out | Calf Muscle Strain | Calf Muscle Strain | Mar 11 |
| Willem Geubbels | F | Out | Thigh Muscle Strain | Thigh Muscle Strain | Nov 14 |
| Sofiane Alakouch | DEF | Out | Knee Injury | Knee Injury | Feb 23 |
| Ousmane Dembele | F | Out indefinitely | Hamstring | Hamstring | Apr 11 |
| Marquinhos | DEF | Out indefinitely | Rib Injury | Rib Injury | Apr 3 |
| Lucas Hernandez | DEF | Out indefinitely | ACL Knee Ligament Injury | ACL Knee Ligament Injury | Apr 11 |
| Fabian Ruiz | MID | Out indefinitely | Illness | Illness | Feb 16 |
| Achraf Hakimi | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Apr 3 |
| Randal Kolo Muani | F | Doubtful | Randal Kolo Muani is Doubtful with Leg injury. | Kolo Muani is doubtful with leg | Oct 12 |
| Vitor Vitinha | MID | Out indefinitely | None | Vitinha is injured | Sep 13 |
| Bradley Barcola | F | Doubtful | Bradley Barcola is Doubtful with Thigh injury. | Barcola is doubtful with thigh | Oct 14 |
| Desire Doue | F | Doubtful | Desire Doue is Doubtful with Calf injury. | Doue is doubtful with calf | Oct 14 |
| Senny Mayulu | MID | Out | Senny Mayulu is expected to return Mid September 2025 from Thigh injury. | Mayulu is out with thigh | Sep 1 |
| Maxime Busi | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Nov 6 |
| Breel Embolo | F | Out | Knee Injury | Knee Injury | Apr 11 |
| Seko Fofana | MID | Out indefinitely | Calf/Shin Injury | Calf/Shin Injury | Sep 16 |
| Przemyslaw Frankowski | DEF | Out | Suspended | Suspended | Mar 13 |
| Alidu Seidu | DEF | Out | Knee Injury | Knee Injury | Mar 19 |
| Mahamadou Nagida | DEF | Out indefinitely | None | Nagida is injured | May 3 |
| Abdelhamid Ait Boudlal | DEF | Out | Abdelhamid Ait Boudlal is expected to return Late October 2025 from Groin injury. | Ait Boudlal is out with groin | Oct 11 |
| Florian Marange | DEF | Out | Ankle Fracture | Ankle Fracture | May 22 |
| Sébastien Squillaci | DEF | Out | ACL Knee Ligament Injury | ACL Knee Ligament Injury | Apr 30 |
| Y. Sylla | MID | Out | Suspended | Suspended | Mar 19 |
| Antony Robic | MID | Out indefinitely | Groin Strain | Groin Strain | Jun 12 |
| H. Manzala | MID | Out indefinitely | Knock | Knock | Feb 10 |
| I. Saadi | A | Out | Knee Injury | Knee Injury | May 14 |
| Rémy Vercoutre | GK | Out | Shoulder Injury | Shoulder Injury | May 19 |
| Romain Genevois | DEF | Out | Knock | Knock | May 30 |
| Mouhamadou Dabo | DEF | Out | Suspended | Suspended | Apr 29 |
| Jonathan Delaplace | MID | Out | Calf Muscle Strain | Calf Muscle Strain | May 19 |
| Emmanuel Imorou | DEF | Out | Illness | Illness | Feb 19 |
| Jordan Adéoti | MID | Out indefinitely | Knock | Knock | Jun 12 |
| Vincent Bessat | MID | Out | Groin/Pelvis Injury | Groin/Pelvis Injury | May 19 |
| Jordan Leborgne | MID | Out indefinitely | Knee Injury | Knee Injury | Apr 23 |
| Ismaël Tiémoko Diomandé | MID | Out | Calf Muscle Strain | Calf Muscle Strain | May 24 |
| Steed Malbranque | MID | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | May 22 |
| Julien Féret | MID | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Jan 10 |
| Valentin Voisin | MID | Out | Knock | Knock | Jan 21 |
| Nicolas Seube | MID | Out indefinitely | Hamstring | Hamstring | Jun 12 |
| Hervé Bazile | A | Out | Thigh Muscle Strain | Thigh Muscle Strain | Dec 7 |
| J. Rivierez | DEF | Out indefinitely | Knock | Knock | Oct 23 |
| Y. Bammou | A | Out | Pubalgia | Pubalgia | Jan 4 |
| Paul Baysse | DEF | Out | LCL Knee Ligament Injury | LCL Knee Ligament Injury | Jan 15 |
| S. Yago | DEF | Out indefinitely | Groin Strain | Groin Strain | Jan 19 |
| Prince Oniangué | MID | Out | Knee Injury | Knee Injury | Jan 31 |
| A. Gonçalves | MID | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Dec 17 |
| Florian Le Joncour | DEF | Out indefinitely | Hamstring | Hamstring | Nov 20 |
| C. Kouakou | A | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | May 7 |
| J. Repas | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | Nov 26 |
| T. Stavitski | A | Out | Illness | Illness | Jan 29 |
| I. Cissé | DEF | Out | Ankle/Foot Injury | Ankle/Foot Injury | Jan 14 |
| Julio Enciso | F | Out indefinitely | None | Enciso is injured | Aug 14 |
| Mamadou Sarr | DEF | Out | Mamadou Sarr is expected to return Late October 2025 from Thigh injury. | Sarr is out with thigh | Oct 1 |
| Emanuel Emegha | F | Out | Emanuel Emegha is expected to return Late October 2025 from Hamstring Injury. | Emegha is out with hamstring | Sep 30 |
| Saidou Sow | DEF | Out indefinitely | Sow, Saidou: missing - injured | Sow is injured | Aug 23 |
| Milos Lukovic | F | Suspended | Milos Lukovic is serving a suspension for Red card. | Lukovic is suspended with red card | Sep 30 |
| Oscar Perea | F | Out indefinitely | Óscar Perea will not play due to National team. | Perea is injured with unknown | Oct 3 |
| Rasmus Nicolaisen | DEF | Out | Suspended | Suspended | Oct 30 |
| Rafik Messali | MID | Out | Rafik Messali is expected to return Late October 2025 from Ankle injury. | Messali is out with ankle | Oct 10 |
AS Nancy
Amiens SC
Clermont Foot 63
Dijon FCO
EA Guingamp
ESTAC Troyes
FC Girondins de Bordeaux
Nîmes Olympique
SC Bastia
SM Caen
