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Cubs vs. Athletics Odds & Betting Predictions - March 21, 2026

Cubs at Athletics

1:10 am • MARQ

Chicago Cubs

11-15
1
1 - 0

Athletics

13-15
0

Cubs at Athletics Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
11-15
N/A
N/A
N/A
Athletics
13-15
N/A
N/A
N/A
location pinSaturday 1:10 a.m.
March 21, 2026
HoHoKam ParkMesa

Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. Athletics Public Betting Percentages

Away Logo

Cubs

Public

Home Logo

Athletics

50%

Bets%

50%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Athletics are 2-3 in their last 5 games.
  • Athletics are 2-3 in their last 5 games against the spread
  • Athletics are 47-34 in their road games against the spread
  • The totals have gone OVER in 2 of Athletics' last 5 games
  • The totals have gone OVER in 40 of Athletics' 81 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Athletics		86-7639-4247-3414-2470-50
Cubs		78-8439-4239-4255-6022-24

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Athletics		77-77-840-39-237-38-614-22-261-53-6
Cubs		74-78-1040-36-534-42-552-56-722-21-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Athletics		76-8636-4540-4117-2156-64
Cubs		92-7050-3142-3973-4218-28

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Mar 20thSEAL 4-6-1.5 LU 12.5SEA -142
Mar 17th@CWSL 4-6+1.5 LU 12.5CWS +100
Mar 16thLAAW 3-0-1.5 WU 11.5ATH -160
Mar 15th@CLEL 6-12+1.5 LO 11.5CLE +125
Mar 14thKCW 12-1-1.5 WO 11.5ATH -168

Athletics vs. Cubs Injury Updates

Athletics Injuries

  • Luis Medina
    SP

    Medina is out with elbow

    Out

Cubs Injuries

  • Justin Steele
    SP

    Steele is out for season with elbow

    Out for Season

See more MLB Injuries Right Arrow
Cubs vs. Athletics Box Score
Cubs Player Stats
Projected
PITCHERPCIPKER
Jameson Taillon logoRJ.Taillon, P251.120
HITTERSH-ABRHRRBI
Michael Busch logo1M.Busch, 1B0-1000
Nico Hoerner logo2N.Hoerner, SS0-1000
Miguel Amaya logo3M.Amaya, C1-1111
Kevin Alcantara logo4K.Alcantara, CF0-1000
Dylan Carlson logo5D.Carlson, LF0-1000
Jonathon Long logo6J. Long, DH0-0000
BJ Murray Jr. logo8B. Murray, 3B0-1000
Kingery logo9S.Kingery, 2B-
Athletics Player Stats
Projected
PITCHERPCIPKER
Luis Severino logoRL.Severino, P36231
HITTERSH-ABRHRRBI
Lawrence Butler logo1L.Butler, RF0-1000
Nick Kurtz logo2N.Kurtz, 1B0-1000
Shea Langeliers logo3S.Langeliers, C0-0000
Tyler Soderstrom logo4T.Soderstrom, LF0-1000
Brent Rooker logo5B.Rooker, DH0-1000
Jacob Wilson logo6J.Wilson, SS1-1000
Jeff McNeil logo7J.McNeil, CF0-0000
Max Muncy logo8M.Muncy, 3B-
Andy Ibanez logo9A.Ibanez, 2B-

Cubs vs. Athletics Odds Comparison

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Cubs at Athletics Team Totals

MatchupOverUnder
Cubs
11-15
N/A
N/A
Athletics
13-15
N/A
N/A