The Guardians host the A's on July 18, 2025. First pitch from Progressive Field is scheduled for 7:10 p.m. ET; the game will be broadcast on CLEG and MLB.TV.
This three-game series opens with JP Sears on the mound for the A's and Slade Cecconi for the Guardians.
Find my A's vs Guardians prediction and MLB betting preview below, as well as probable pitchers, betting trends, injury reports and more.
A's vs Guardians Prediction, Picks
- A's vs Guardians Pick: F5 Innings Under 4.5 (-118 · BetMGM)
My Guardians vs. A's best bet is under 4.5 for the first five innings. Make sure to find the best odds by checking our live MLB odds page.
A's vs Guardians Odds, Line, Spread
| Athletics Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
+1.5 -190 | 8 -105o / -115u | +110 |
| Guardians Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
-1.5 +158 | 8 -105o / -115u | -130 |
A's vs Guardians Projected Pitchers
| LHP JP Sears (ATH) | Stat | RHP Slade Cecconi (CLE) |
|---|---|---|
| 7-7 | W-L | 4-4 |
| 0.6 | fWAR (FanGraphs) | 0.4 |
| 4.79 / 4.00 | ERA / xERA | 3.44 / 4.76 |
| 4.88 / 4.71 | FIP / xFIP | 4.26 / 3.89 |
| 1.25 | WHIP | 1.27 |
| 13.3 | K-BB% | 16.4 |
| 29.5 | GB% | 38.3 |
| 96 | Stuff+ | 93 |
| 104 | Location+ | 105 |
A's vs Guardians Pick, Best Bets
This Cleveland team is starting to become one of my first looks of any slate for some of these first five innings totals, as it has some good starting pitchers and just a putrid offense.
This is one of the worst teams in baseball against left-handed pitchers, and while Sears is surely not good, the Guardians are just so weak outside of Jose Ramirez and maybe Angel Martinez.
On the other side, the Athletics have some power, but I trust Cecconi to limit them here.
Pick: First 5 Innings Under 4.5 (-118 · BetMGM)
A's vs Guardians Betting Trends
