The St. Louis Cardinals host the Milwaukee Brewers on May 6, 2026. First pitch from Busch Stadium is scheduled for 1:15 p.m. EDT. The game will be broadcast on CARD.
The Brewers are -106 on the moneyline. The Cardinals are -110 on the moneyline. The total is set at 8 runs.
Find my MLB picks and Brewers vs Cardinals prediction below, as well as probable pitchers, weather report, and more.
Brewers vs Cardinals Predictions, Pick
- Brewers vs Cardinals Pick: Under 8.5
My Brewers vs Cardinals best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.
Brewers vs Cardinals Odds, Run Line, and Over/Under
| Brewers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +162 | 8 -112o / -108u | -106 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -200 | 8 -112o / -108u | -110 |
- Brewers vs Cardinals moneyline: Brewers -106, Cardinals -110
- Brewers vs Cardinals over/under: 8.5 (-112 / -108)
- Brewers vs Cardinals spread: Brewers -1.5 (+162), Cardinals +1.5 (-200)
Brewers vs Cardinals Probable Pitchers
| Brandon Sproat (RHP, MIL) | Stat | Andre Pallante (RHP, STL) |
|---|---|---|
| 0-2 | W-L | 3-2 |
| -0.3 | fWAR (FanGraphs) | 0.1 |
| 6.75 / 5.28 | ERA / xERA | 3.73 / 4.41 |
| 6.37 / 4.77 | FIP / xFIP | 4.68 /4.61 |
| 8.7% | K-BB% | 8.7% |
| 37.0% | GB% | 50.0% |
| .309 | BABIP | .250 |
| 100 | Stuff+ | 94 |
| 96 | Location+ | 95 |
Brewers vs Cardinals Expert MLB Pick
This game triggered one of our Action PRO betting systems, powered by Evan Abrams.
Weather Watch Unders is a system built for MLB totals bettors who understand how environmental factors quietly shift run production.
This approach keys in on games with moderate to strong winds — especially those blowing in or cross-field — paired with mild to cool temperatures, a known recipe for stifled fly balls and reduced scoring.
When totals open high, but tick down before the first pitch, it signals sharp money reacting to these same weather cues.
With home moneyline ranges excluding extreme mismatches, the model focuses on contests where weather can truly swing scoring.
How To Bet My Brewers vs Cardinals Pick, Best Bet
The run-scoring environment should be brutal at Busch Stadium today, with temperatures in the mid-50s and double-digit winds blowing in from left field. BallParkPal's weather model projects a -16% run-scoring factor for this matchup, lowering his projected total by 1.39 runs compared to a weather-neutral day.
Pick: Under 8.5
