The Milwaukee Brewers host the Houston Astros on May 5, 2025. First pitch from American Family Field is scheduled for 7:40 p.m. ET; the game will be broadcast on SCHN.
The Astros dropped a rain-shortened game to the Chicago White Sox, so they'll look to prevent a losing skid against the Milwaukee Brewers, who shut the Cubs out on Sunday.
Find my MLB betting preview and Astros vs Brewers prediction below.
My Astros vs Brewers Prediction
- Astros vs Brewers picks: Astros Moneyline (-105; play to -130)
My Astros vs Brewers best bet is the Astros moneyline . Make sure to find the best odds by checking our live MLB odds page.
Astros vs Brewers Odds
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +154 | 8 -112o / -108u | -105 |
| Brewers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -185 | 8 -112o / -108u | -115 |
Astros vs Brewers Projected Starting Pitchers
| Ronel Blanco (HOU) | Stat | Tobias Myers (MIL) |
|---|---|---|
| 2-2 | W-L | 0-0 |
| 0.1 | fWAR (FanGraphs) | -0.1 |
| 5.08/3.47 | ERA /xERA | 5.14/3.86 |
| 5.00/4.72 | FIP / xFIP | 6.63/6.60 |
| 1.31 | WHIP | 1.86 |
| 10% | K-BB% | -2.9% |
| 32.1% | GB% | 40% |
| 91 | Stuff+ | 87 |
| 100 | Location+ | 83 |
Sean Paul’s Astros vs Brewers Preview
Milwaukee Brewers Betting Preview: Struggles Amount for Brew Crew
Many people had Milwaukee winning the NL Central despite serious rotation question marks. Outside of Freddy Peralta, the most “reliable” option was Tobias Myers, another source of concern this year.
The Brewers are hoping the second-year starter, Myers, can find his form from his rookie season. Myers was among the best rookie starters in MLB last year, posting a 3.00 ERA. Although Myers doesn’t have game-changing stuff, he found a way to get outs.
In Myers’s most recent outing, he pitched one inning of relief, likely just for some extra work after a pair of uninspiring starts. It’s tough to take much from Myers’s underlying numbers since he’s thrown just seven innings in two starts.
He enters with a 5.14 ERA with a 3.86 xERA, but a troubling 6.63 FIP and 6.60 xFIP. We’ll see which of the numbers tells the actual tale. The truth is probably somewhere in the middle, and Myers will eventually settle in the mid to high 4-era department.
On the offensive end, it’s been a shocking struggle for the Brewers. They rank 18th in MLB with a 93 wRC+ since April 15th. It’s not like the Brewers swing and miss a lot or have poor plate patience. Milwaukee ranks 3rd in strikeout rate in that span and seventh in walk rate.
So, why is Milwaukee so mediocre?
Look no further than the 11 homers in the last 17 games. That’s one of the worst marks in MLB, and the hitters who are supposed to provide the power, Christian Yelich, William Contreras, and Jackson Chourio, have gone yard just three times in those 17 games. That'll need to change for the Brewers to figure things out.
Houston Astros Betting Preview: Optimism in H-Town?
It's a new era for the Houston Astros, as Alex Bregman is hitting homers over the Green Monster, and Kyle Tucker is fighting the ivy for fly balls at Wrigley.
However, the Astros aren't to be taken lightly. Houston ranks 12th in wRC+ since April 15, which is the start of what could be an elite offense.
Why am I so optimistic about the Astros?
The sudden surge in hitting has come with Yordan Alvarez hitting below .200 and Jose Altuve posting a wRC+ below 80. That clearly won't last given the pedigree of Altuve, a former MVP, and Alvarez, one of the sport's premier sluggers. Worth noting that Alvarez didn't play in the last two games with right-hand inflammation but could return on Monday.
Ronel Blanco, similar to Myers, shone in 2024 in his full season as an MLB starter. Blanco finished the year with a 2.80 ERA, with all his expected numbers hovering around the 4.00 range. This year, Blanco has pivoted from lucky to unlucky.
Entering Monday, Blanco has an ugly 5.08 ERA with a more palatable 3.47 xERA. If Blanco wants to turn the tide, it begins with getting ahead in counts and cutting down his ugly 4.46 BB/9. When a pitcher fails to get ahead in counts, it also leads to throwing more hittable pitches to get back in the count. That shows in Blanco's rough 1.53 HR/9, but the Brewers don't hit homers, so that point could prove moot.
Astros vs Brewers Prediction, Betting Analysis
I like the Astros here. I trust Blanco way more than Myers, who the Brewers can't be optimistic about, given his brutal start to 2025. If Myers can't get past five innings again, it'll put tons of pressure on Milwaukee's bullpen to be perfect, and it has the third-worst bullpen ERA in MLB. In comparison, the Astros are fourth in bullpen ERA, so that's a huge advantage for them.
I'll take the slight underdog here, who has the better starter, lineup, and pen.
Pick: Astros Moneyline (-105; play to -130)
Moneyline
As mentioned above, the Astros have the advantage in all facets, so I'll play Houston moneyline.
Run Line (Spread)
No play on the run line here.
Over/Under
While both pitchers enter the game with a 5+ ERA, I'll opt not to bet the total.
