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Dodgers vs Padres Prediction, Pick, MLB Odds for Saturday, June 27

Dodgers vs Padres Prediction, Pick, MLB Odds for Saturday, June 27 article feature image
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William Liang-Imagn Images

Pictured: Yoshinobu Yamamoto

The San Diego Padres host the Los Angeles Dodgers on June 27, 2026. First pitch from Petco Park is scheduled for 8:40 p.m. EDT. The game will be broadcast on SDPA.

The Dodgers are favored by -205 on the moneyline and by -1.5 on the run line. The Padres are +172 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Dodgers vs Padres prediction below, as well as probable pitchers, weather report, and more.


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Dodgers vs Padres Prediction

  • Dodgers vs Padres Pick: Yoshinobu Yamamoto Over 6.5 Strikeouts (+114, FanDuel)

My Dodgers vs Padres best bet is Yoshinobu Yamamoto to go over his strikeout prop. Make sure to find the best odds by checking our live MLB odds page.


Dodgers vs Padres Odds

Dodgers Logo
Saturday, Jun 27
8:40 p.m. ET
SDPA
Padres Logo
Dodgers Odds
SpreadTotalMoneyline
-1.5
-118
8
-110o / -110u
-205
Padres Odds
SpreadTotalMoneyline
+1.5
-102
8
-110o / -110u
+172
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Dodgers vs Padres moneyline: Dodgers -205, Padres +175
  • Dodgers vs Padres over/under: 8 (-110o / -110u)
  • Dodgers vs Padres spread: -1.5 (-118), +1.5 (-102)

Dodgers vs Padres Kalshi MLB Odds


Dodgers vs Padres Probable Pitchers

Yoshinobu Yamamoto (RHP)StatRandy Vasquez (RHP)
7-5W-L6-5
2.3fWAR (FanGraphs)0.6
2.65/3.35ERA / xERA4.17/6.51
3.30/3.19FIP / xFIP4.51/4.82
19.8K-BB%10.2
49GB%35.1
.227BABIP.309
103Stuff+98
107Location+101

Dodgers vs Padres MLB Betting Preview

Dodgers' ace Yoshinobu Yamamoto has really rounded into form of late. Over his last five starts, he holds a 1.56 ERA as his stuff has been very nasty.

When Yoshi is right, his stuff does not need to be in the zone for him to dominate, and that's exactly what we've been seeing. In the same span, his chase rate is elite at 35.9 percent, while his first pitch strike rate is below average.

His CSW is still above average, but he has not racked up the strikeouts. All these numbers point to that changing tonight, especially when you factor in the matchup.

Until this season, the San Diego Padres had maintained a profile of a lineup that was the best in the National League at putting the ball in play and threatening power from their stars. However, this year they have taken a big step back, especially against right-handed pitching.

The Padres hold the fifth-lowest wRC+ against righties and the sixth-highest strikeout rate. The strikeouts are way up as a whole, and their discipline has gone out the window.

San Diego is in the bottom third of the league in contact rate, swinging strike rate, and chase rate. This is a lineup that Yamamoto can feast on, as San Diego does not pose a threat in the zone, nor do they have the discipline to lay off pitches outside the zone.

Look for Yamamoto to stay hot and pile up the strikeouts tonight.

Pick: Yoshinobu Yamamoto Over 6.5 Strikeouts (+114, FanDuel)


Dodgers vs Padres Weather


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About the Author

Doug is a college football, college basketball and MLB contributor at the Action Network. He produces content centered around actionable advice with the goal of helping readers become better bettors. He studied journalism at Rutgers and has previously covered the New York Mets, Indianapolis Colts, and Mid-Atlantic region for Perfect Game.

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