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Yankees vs Giants Prediction, Pick, MLB Odds for Friday, March 27

Yankees vs Giants Prediction, Pick, MLB Odds for Friday, March 27 article feature image
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Rick Scuteri-Imagn Images. Pictured: Robbie Ray.

The San Francisco Giants (0-1) host the New York Yankees (1-0) on March 27, 2026. First pitch from Oracle Park is scheduled for 4:35 p.m. EDT. The game will be broadcast on NBCS-BA.

The Yankees are favored by -122 on the moneyline and by 1.5 (+130) on the run line. The Giants are +104 on the moneyline and +1.5 (-156) on the run line. The total is set at 7.5 runs.

Find my MLB picks and Yankees vs Giants prediction below, as well as probable pitchers, weather report, and more.


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Yankees vs Giants Prediction

  • Yankees vs Giants Pick: Over 7.5

My Yankees vs Giants best bet is on game totals. Make sure to find the best odds by checking our live MLB odds page.


Yankees vs Giants Odds

Yankees Logo
Friday, Mar 27
4:35 p.m. ET
NBCS-BA
Giants Logo
Yankees Odds
SpreadTotalMoneyline
-1.5
+130
7.5
-122o / -100u
-122
Giants Odds
SpreadTotalMoneyline
+1.5
-156
7.5
-122o / -100u
+104
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Yankees vs Giants spread: Yankees -1.5 (+130), Giants +1.5 (-156)
  • Yankees vs Giants over/under: 7.5 (-122 / -100)
  • Yankees vs Giants moneyline: Yankees -122, Giants +104

Yankees vs Giants Projected Starting Pitchers

RHP Cam Schlittler (NYY)StatLHP Robbie Ray (SFG)
Season DebutW-LSeason Debut
fWAR (FanGraphs)
ERA /xERA
FIP / xFIP
WHIP
K-BB%
GB%
Stuff+
Location+

Yankees vs Giants Betting Preview

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New York Yankees Betting Preview

The betting public was all hyped up and ready to get some home run bets in for the Yanks' season's first game. And what did Aaron Judge, Rafael Devers, and company deliver? A goose egg in homers.

But this is a much different pairing of pitchers. Game one featured two of the game's elite home run suppressors — Max Fried and Logan Webb. Game two has no such thing. We've got Robbie Ray (47% FB%, 1.76 HR/9 in 2025) hosting Cam Schlittler (38% FB%, 0.99 HR/9 in 2025).

Ray is a known commodity, albeit an old one. And Schlittler is one of the new guys on the block. Ray has nine years on his counterpart in this one, and they throw with opposite hands. But they're both guys with histories of strikeouts, walks, and home runs allowed. The "three true outcome" pitcher, if you will.

Both guys throw a bunch of four-seam fastballs (Ray around 94mph, Schlittler around 98mph) with a pretty solid breaker behind it (Ray a slider, Schlittler a curve). So it's two very different pitchers who still attack and get the ball in play in basically the same way. And that is where we focus our attention.

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San Francisco Giants Betting Preview

On the Giants' starting pitching front, we have basically the opposite of what we had on opening night. Fried and Webb brought elite walk rates and higher ground ball rates to the table, without a ton of strikeout upside. The two arms going in this one bring big strikeout potential with spotty command and a bunch of balls allowed to be hit in the air.

As for the fantasy — which I actively keep an eye on every year — everything I looked at with these two pointed to a massive fade of both guys. I don't believe I have a single share of either one. Yesterday was a great example of how unreliable starting pitching can be early in the year. I'm betting on some offense in this game.


Yankees vs Giants Pick, Betting Analysis

It's a very interesting "compare and contrast" with these two SPs. I feel like you could write a book about it. In another similarity, I think the public will hold too high an opinion of each guy, albeit for different reasons.

Robbie Ray threw 182.1 innings last year, and that followed a completely lost season after a Tommy John that cost him his 2024 season. It was an impressive volume feat. But what you might not have noticed is that he lost a good bit of strikeout ability. His 24.6% K% last year came in four points below his career average.

The thing a lot of people remember about Cam Schlittler is the dominant outing he had in the postseason last year against the Red Sox. He threw eight scoreless with 12 strikeouts under the brightest lights of a postseason elimination game. What we don't remember as much is the 10.2% BB% he posted in his Major League time, along with the dangerous game he plays, allowing fly balls as we've already talked about.

Speaking of short memories, all of the talk is negative on Aaron Judge right now. A lackluster WBC and then a huge 0/5 with four strikeouts in the season's first game. By the way, I don't believe the books are going to downgrade the guy in any way, but the public's money just might push toward this 'anti-Judge' side if this trend continues.

It's a great spot for him against Robbie Ray. Judge is one of the best to ever hold a baseball bat. I'd like to be on his side when the crowd starts to lean against him.

The books are dragging their feet on the walk lines, so I can't say it for sure — but I'll be very curious to see if we can get a reasonable price on over 1.5 walks for either guy, particularly Schlittler against this patient Giants lineup.

Pick: Over 7.5 Runs (-115)

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Yankees vs Giants Weather


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Jon AndersonVerified Action Expert

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