The Colorado Rockies host the San Diego Padres on April 22, 2026. First pitch from Coors Field is scheduled for 8:40 p.m. EDT. The game will be broadcast on SDPA.
The Padres are favored by -162 on the moneyline and by -1.5 on the run line. The Rockies are +136 on the moneyline and +1.5 on the run line. The total is set at 12 runs.
Find my MLB picks and Padres vs Rockies prediction below, as well as probable pitchers, weather report, and more.
Padres vs Rockies Prediction
- Padres vs Rockies Pick: Fernando Tatis Jr. Home Run (+379 or Better)
Padres vs Rockies Odds
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -110 | 12 -115o / -105u | -162 |
| Rockies Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -110 | 12 -115o / -105u | +136 |
- Padres vs Rockies moneyline: Padres -162, Rockies +136
- Padres vs Rockies over/under: 12 (-115o / -105u)
- Padres vs Rockies spread: Padres -1.5 (-110), Rockies +1.5 (-110)
Padres vs Rockies MLB Betting Preview
By Derek Carty
THE BAT X is forecasting 0.27 home runs for Fernando Tatis Jr.
Oddsmakers are implying 0.21 home runs, so I believe there is value.
If you take the over, you'd be projected to win 23% of the time, resulting in a 26% ROI with an expected value of $26.34 (based on a $100 wager).
This play is good down to at least +379.
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Pick: Fernando Tatis Jr. Home Run (+379 or Better)
