The Washington Nationals host the San Diego Padres on May 31, 2026. First pitch from Nationals Park is scheduled for 1:35 p.m. ET. The game will be broadcast on SDPA.
The Padres are favored by -134 on the moneyline and by -1.5 on the run line. The Nationals are +114 on the moneyline and +1.5 on the run line. The total is set at 9 runs.
Find my MLB picks and Padres vs Nationals prediction below, as well as probable pitchers, weather report, and more.
Padres vs Nationals Prediction
Padres vs Nationals Picks:
- CJ Abrams Over 1.5 HRR (-115)
- James Wood Home Run (+390)
Padres vs Nationals Odds
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +132 | 9 -115o / -105u | -134 |
| Nationals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -160 | 9 -115o / -105u | +114 |
Padres vs Nationals Probable Pitchers
| Griffin Canning (RHP, SDP) | Stat | Zack Littell (RHP, WSN) |
|---|---|---|
| 0-3 | W-L | 4-4 |
| 0.0 | fWAR (FanGraphs) | -0.8 |
| 7.54 / 4.56 | ERA / xERA | 5.23 / 6.55 |
| 4.96 / 4.04 | FIP / xFIP | 6.61 / 5.44 |
| 11.1% | K-BB% | 5.5% |
| 46.8% | GB% | 33.5% |
| .310 | BABIP | .244 |
| 92 | Stuff+ | 83 |
| 90 | Location+ | 96 |
Padres vs Nationals MLB Betting Preview
Through five starts, Griffin Canning has recorded an obscene 7.54 ERA and 1.54 WHIP. He’s allowed 19 earned runs in less than 23 innings.
I expect Canning to again get rocked against a solid Washington lineup, so I’m targeting two Nationals in the player props market.
Padres vs Nationals Pick, Betting Analysis
In eight previous head-to-head at-bats against Canning, CJ Abrams has four hits, including two doubles and a homer. And let’s not forget the revenge angle — Abrams was traded from San Diego to Washington in the Juan Soto deal.
Additionally, James Wood is 3-for-7 with a homer in previous matchups with Canning. He’s already smashed 15 home runs this season, fueling his .936 OPS.
Picks:
- CJ Abrams Over 1.5 HRR (-115)
- James Wood Home Run (+390)
