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Giants vs Cubs Prediction, Pick, MLB Odds for Friday, June 5

Giants vs Cubs Prediction, Pick, MLB Odds for Friday, June 5 article feature image
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Pictured: San Francisco Giants pitcher Robbie Ray. (Credit: Matt Kartozian-Imagn Images)

*Editor's Note: Edward Cabrera is starting in place of Ben Brown

The Chicago Cubs host the San Francisco Giants on June 5, 2026. First pitch from Wrigley Field is scheduled for 2:20 p.m. EDT. The game will be broadcast on MARQ.

The Cubs are favored by -168 on the moneyline and by -1.5 (+119) on the run line. The Giants are +139 on the moneyline and +1.5 (-143) on the run line. The total is set at 11 runs.

Find my MLB picks and Giants vs Cubs prediction below, as well as probable pitchers, weather report, and more.


Giants vs Cubs Odds, Picks

Giants Logo
Friday, Jun 5
2:20 p.m. ET
MARQ
Cubs Logo
Giants Odds
SpreadTotalMoneyline
+1.5
-143
11
-105o / -115u
+139
Cubs Odds
SpreadTotalMoneyline
-1.5
+119
11
-105o / -115u
-168
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo

My Giants vs Cubs best bets are Nico Hoerner to clear his total bases line and Robbie Ray to stay under his strikeout prop. Make sure to find the best odds by checking our live MLB odds page.


Giants vs Cubs Probable Pitchers

LHP Robbie Ray (SFG)StatRHP Edward Cabrera (CHC)
3-6W-L3-2
-0.3fWAR (FanGraphs)0.4
4.45/5.18ERA / xERA4.00/4.47
5.40/4.67FIP / xFIP4.46/3.98
10.4%K-BB%11.9%
30.9%GB%43.2%
.265BABIP.298
98Stuff+93
92Location+104

Giants vs Cubs MLB Betting Preview

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San Francisco Giants Betting Preview

Robbie Rayhasn't helped the cause for the fourth-place Giants. He has a 4.45 ERA this year, and it's been nearly a month since he's completed five innings. His walk rate sails way up there at 11.5%, and he's walked 15.2% of hitters in his last five outings.

So what's gone wrong for the veteran lefty? I think this is just what can happen when you get old and no longer have a fastball you can trust. He's not wanting to throw that pitch in the zone because he knows what can happen to it. The four-seamer has given up a .480 xwOBA in this recent stretch, so he's trying to paint the corners with it and often missing for a 40% Ball% on the pitch.

In the same way, the slider has a .434 xwOBA allowed in the last five starts. It gets a few whiffs, but it's still a bad 12.3% SwStr% when you consider the pitch type. Sliders should be 15%+ to be effective.

We saw Ray try to change something last time out in response. He threw 20 sinkers, a brand new pitch for him this year. And he landed the sinker for a strike with ten of those pitches. He threw 34 four-seamers, 25 sliders, and 20 of these sinkers. So I think he'll go back to it in this one.

And this is a spot to get ahead of the books, because they aren't going to be pricing in a new pitch. What we know about sinkers is that they don't get whiffs. The pitch doesn't have movement that misses bats. And I'm not talking about Ray's sinker only, it's just a general principle across baseball. The Cubs already do a really nice job with the strikeout. They have a team 20.7% K% against lefties, a couple of points below the league average.

So we're looking at the under on Ray's strikeouts, first of all.

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Chicago Cubs Betting Preview

I like Nico Hoerner's matchup a lot here. He's an elite hitter against lefties and has a .315 xBA against southpaws this year. He doesn't strike out and doesn't walk, so he's going to get a few balls in play in this one. The best way to bet on him would be through markets that reward hits and runs.


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Giants vs Cubs Pick, Betting Analysis

The theme of the day is new sinkers. Ray's just started throwing this sinker last start as he tries to find something, anything that will work.

Here's what I like:

  • Nico Hoerner H+R+SB overs
  • Robbie Ray strikeout unders

Picks: Hoerner Over 1.5 Total Bases (-111), Ray Under 4.5 K (+125)


Giants vs Cubs Weather


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Jon AndersonVerified Action Expert

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