The New York Knicks (34-20) and Philadelphia 76ers (30-23) will square off in the NBA on Wednesday night. Tipoff from Xfinity Mobile Arena in Philadelphia, Pennsylvania is set for 7:30 p.m. ET on ESPN.
The Sixers are 2.5-point favorites over the Knicks on the spread (76ers -2.5), with the over/under set at 225.5 total points. Philadelphia is a -130 favorite to win outright on the moneyline, while New York is +110 to pull off the upset.
Let's get into my Knicks vs. 76ers predictions and NBA picks for Wednesday, February 11.
Knicks vs 76ers Prediction
- Knicks vs 76ers pick: 76ers -2.5 (-110)
My 76ers vs. Knicks best bet is on Philadelphia to cover the spread at -2.5. Make sure to find the best odds by checking our live NBA odds page.
New York Knicks vs Philadelphia 76ers Odds
| Knicks Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+2.5 -110 | 225.5 -110o / -110u | +110 |
| 76ers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-2.5 -110 | 225.5 -110o / -110u | -130 |
Knicks vs 76ers NBA Wednesday Preview
There’s no telling who’s going to play for the Knicks tonight. This is their Vaya Con Dios game with the All-Star break starting immediately after.
Jalen Brunson and Karl-Anthony Towns may get a head start on heading to L.A., and the rest of the team may head to whatever tropical isle they'll spend the week on.
OG Anunoby and Mitchell Robinson rested Tuesday night, so you’d assume they play.
For the 76ers, Joel Embiid is questionable as always, along with Quentin Grimes and Dominick Barlow.
This is all about the spot. The Sixers are 8-3 ATS this season against teams on a back to back.
How’s this for a crazy trend? Teams are 1-7 SU this year on a back-to-back after playing the Pacers, and 2-6 ATS. The pace seems to take something out of them.
The Knicks are a dominant offensive rebounding team, but there’s a stat that is downright puzzling in relation to that:
This season, when facing an opponent who is below-average in defensive rebounding, the Knicks are worse against the number, going 13-20 (39.4%) ATS. The Sixers are a below-average defensive rebounding team.
This line is below the average Knicks line, thanks to the road back-to-back spot, and in games where the line is worse than the Knicks’ average line, New York is 10-15 ATS this season.
My model leans Knicks here as long as three starters play, but the circumstances are extenuating, and the matchup isn’t great.
Philadelphia has the speed to get downhill on a tired Knicks team.
Tyrese Maxey should generate good looks out of pick-and-roll and the Sixers’ depth is in a good spot to find open looks.
Knicks vs 76ers Picks, Best Bets
76ers -2.5
If Brunson sits, the Knicks record is 1-4 SU and ATS without him this season.
If Brunson is not there to lead New York's offense, it likely stalls out, and the defense is pretty even with the Sixers.
If Embiid plays, Mitchell Robinson is a good matchup for him, but Embiid can put him in foul trouble.
I’m expecting a sluggish, ugly game (lean under) that the Sixers manage to win to send the Knicks into the break with a disappointing two-game losing streak after their recent hot streak.

Kelly Oubre Over 1.5 Three-Pointers Made
Oubre leads the Sixers in corner three-point attempts and is shooting 47% from those spots.
The Knicks give up the fifth-most corner three-point attempts in the league.

Joel Embiid Under 36.5 Points & Rebounds
Embiid will struggle with Robinson on the glass, and takes more of his shots from mid-range than he does in the paint.
The Knicks give up a low percentage of mid-range shots and allow a low conversion percentage as well.
Embiid will likely have a quieter game than most are expecting.

Knicks vs 76ers Betting Predictions
- 76ers -2.5 (-110)
- Kelly Oubre Over 1.5 Three-Pointers Made (-140)
- Joel Embiid Under 36.5 Points & Rebounds (-112)
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