Louisville vs. Clemson Odds & Betting Predictions - February 28, 2026

Louisville at Clemson

7:00 pm • ESPN2
75 - 80

Louisville at Clemson Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Louisville
23-10
-1.5
-2-112
o147-112
-138
Clemson
24-10
u145.5
+2-107
u147-110
+115
location pinSaturday 7:00 p.m.
February 28, 2026
Littlejohn ColiseumClemson
Louisville vs. Clemson Expert Picks
CTO
CTO
Last 30d: 21-23-0 (-2.8u)
CLEM +105
2.1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 117-126-4 (-23.3u)
CLEM +1.5-110
1u
John Feltman
John Feltman
Last 30d: 53-50-1 (-2.3u)
CLEM +1.5-110
0.5u
Stuck 🚨
Stuck 🚨
Last 30d: 58-71-4 (+0.2u)
CLEM +2-110
0.36u
Mike McNamara
Mike McNamara
Last 30d: 102-130-2 (+4.9u)
CLEM +2-110
0.3u
JMann
JMann
Last 30d: 45-50-0 (+0.1u)
CLEM +105
1.05u
Sean Paul
Sean Paul
Last 30d: 28-36-0 (-8.4u)
LOU -1.5-103
1u
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Louisville vs. Clemson Previews & Analysis

  • Louisville vs Clemson: This Side is Mediocre article feature image

    Louisville vs Clemson: This Side is Mediocre

    Sean Paul
    Feb 28, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Louisville vs. Clemson Public Betting Percentages

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Louisville

Public

66%

Bets%

34%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Clemson
18-169-109-614-144-2
Louisville
15-189-96-911-131-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Clemson
14-207-127-812-162-4
Louisville
12-215-137-89-151-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Clemson
24-10N/AN/A23-51-5
Louisville
23-10N/AN/A17-71-3

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Feb 21stFSUL 65-70-8.5 LU 145.5FSU -440
Feb 19th@WAKEL 77-85-3.5 LO 140WAKE -190
Feb 14th@DUKEL 54-67+13.5 WU 134DUKE +720
Feb 12thVTL 66-76-8.5 LO 138.5VT -400
Feb 8th@CALW 77-55-4.5 WU 139.5CLEM -198
Team Stats
29-64 (45%)
Field Goals
24-49 (49%)
7-12 (58%)
Free Throws
24-34 (71%)
10-36 (28%)
3P
8-21 (38%)
33
Rebounds
30
12
Assists
12
11
Turnovers
9
5
Steals
9
3
Blocks
3
23
Fouls
15

Louisville vs. Clemson Odds Comparison

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Louisville at Clemson Team Totals

MatchupOverUnder
Louisville
23-10
N/A
N/A
Clemson
24-10
N/A
N/A