The Louisville Cardinals take on the Indiana Hoosiers in Nassau, Bahamas, as part of the Battle 4 Atlantis. Tip-off is set for 12 p.m. ET on ESPN.
The Hoosiers are favored by 3 points on the spread with a moneyline of -148. The total is set at 154 points.
Here’s my Louisville vs. Indiana predictions and college basketball picks for November 27, 2024.
Louisville vs Indiana Prediction
My Pick: Indiana -1.5
My Louisville vs Indiana best bet is on the Hoosiers spread, with the best odds currently available at FanDuel. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.
Louisville vs Indiana Odds, Spread
| Louisville Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+3 -1115 | 154 -112 / -108 | +124 |
| Indiana Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-3 -105 | 154 -112 / -108 | -148 |
- Louisville vs Indiana spread: Indiana -3
- Louisville vs Indiana over/under: 154 points
- Louisville vs Indiana moneyline: Indiana -148, Louisville +124
- Louisville vs Indiana best bet: Indiana -1.5
My Louisville vs Indiana NCAAB Betting Preview
The Battle 4 Atlantis tips off on Wednesday with two teams that could really use a statement win. Pat Kelsey is searching for his first big victory at Louisville, and Mike Woodson looks to restore faith that this could be the year for Indiana fans.
Indiana enters this game with a flawless 4-0 record, but the Hoosiers have had a handful of uninspiring halves along the way, trailing Eastern Illinois after 20 minutes and letting UNC Greensboro hang around for far too long.
On the other end, Louisville has been business-like in its three wins, disposing of Winthrop, Bellarmine and Morehead State by comfortable margins.
The Cardinals' lone game against an NCAA Tournament-caliber squad was ugly though, as Tennessee slaughtered Kelsey's squad in their home gym (days after Kelsey promoted videos of himself encouraging fans to "Pack the Yum").
It remains to be seen if Kelsey's crowd-begging skills will translate to Atlantis, or if his teams can win games against quality opponents even if they have the crowd advantage. Kelsey's teams are just 3-27 outright in 30 career games against KenPom top-75 opponents.
Louisville wants to shoot as many 3s as possible, as Kelsey's teams always do. On the season, the Cardinals rank second nationally in 3-point attempt rate, but the shots aren't falling just yet.
The Cardinals make only 29% from 3 as a team, a whopping 6% worse than an Indiana team that is often criticized for its inability to shoot.
This year's game could be decided by star power, and Indiana has the decisive advantage in that category. Woodson's transfer portal class features point guard Myles Rice — who has been the Hoosiers' best player in their brightest moments this season — and former Arizona center Oumar Ballo.
There is an argument to be made that Indiana has the four best players in this game, as two of Louisville's biggest stars (Kasean Pryor and Terrence Edwards Jr.) have both logged single-digit points in multiple games already this season.
Given Kelsey's track record in big games and Indiana's advantage physically, the safe bet is on the Hoosiers to cover.
