The No. 10 Nebraska Cornhuskers (15-0) take on the Indiana Hoosiers (12-3) in Bloomington, Indiana. Tip-off is set for 12 p.m. ET on BTN.
Indiana is favored by 4.5 points on the spread with a moneyline of -210. The total is set at 151.5 points.
Here’s my Nebraska vs. Indiana prediction and college basketball picks for January 10, 2026.
Nebraska vs. Indiana Odds, Spread
| Nebraska Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+4.5 -102 | 151.5 -110o / -110u | +172 |
| Indiana Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-4.5 -120 | 151.5 -110o / -110u | -210 |
My Pick: Indiana ML -205
My Nebraska vs Indiana best bet is on the Hoosiers to win outright. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.
Nebraska vs Indiana NCAAB Betting Preview
Nebraska arrives in Bloomington undefeated, which is impressive. Still, records don’t always tell the full story, and lately, this team has just managed to scrape by. The Huskers are a solid squad, but calling them unbeatable seems like a stretch.
Indiana's offense is where the matchup starts to shift. The Hoosiers rank in the top 30 nationally in adjusted offensive efficiency, and it's not because of gimmicks or luck.
They’re also top-25 in effective field goal percentage and top-15 in 2-point shooting, proving they get quality looks near the basket. That’s important against a Nebraska defense that's been solid to start the season.
Nebraska’s defensive numbers seem strong at first glance, but Indiana is more than capable of combating that, especially at home.
The Hoosiers also rank in the top 100 nationally in free-throw rate, while Nebraska struggles to keep teams off the line. That combination is tough to overcome, especially on the road, where physical teams often get calls.
This aggressive defensive style is part of Nebraska’s identity.
Offensively, the Cornhuskers rely heavily on 3-pointers, with over a third of their points coming from beyond the arc.
They’re among the top 40 teams in 3-point dependence. That could be effective here, but it's more likely that they have an off night. Indiana’s defense ranks in the top 15 nationally at limiting 3-point percentage and forces shooters into tough attempts late in the shot clock.
If Nebraska isn’t hitting 3s, it’s hard to see where its easy points will come from. The Huskers rarely get to the free-throw line, ranking outside the top 250 in free-throw rate, and Indiana’s defense is disciplined enough to limit those opportunities.
In close games, this often makes the difference down the stretch, as one team gets free points while the other settles for jump shots.
Indiana also stands out for its experience and poise. The Hoosiers have the most experienced roster in the country, which leads to better decisions on the court. They take care of the ball, ranking above the national average in turnover rate.
Meanwhile, Nebraska’s defense is outside the top 200 when it comes to forcing turnovers. This means Nebraska gets fewer chances for easy transition points and has to rely more on its half-court offense.
Nebraska’s undefeated streak has come with some close calls. The Huskers have won games thanks to shooting luck and late-game variance that's gone wildly in their favor. That’s not a formula you want to trust for long, especially on the road against a tough, experienced Big Ten team.
I'm not backing down after getting burned by the Buckeyes on Monday night. I'll happily fade Nebraska here. Indiana has the edge in shot quality, free throws, experience and home-court advantage.
The Cornhuskers are a good team, but they’re not invincible, and this is where their weaknesses could show.
Take the Hoosiers at home to give Nebraska its first loss.
My Pick: Indiana ML -205
