Kansas vs. Iowa State Odds & Betting Predictions - November 22, 2025

Kansas at Iowa State

4:00 pm

Kansas Jayhawks

@

Iowa State Cyclones

MatchupOpenSpreadTotalMoneyline
Kansas 5-5	N/A	N/A	N/A
Iowa State 6-4	N/A	N/A	N/A

location pin

Saturday 4:00 p.m.

November 22, 2025

Jack Trice StadiumAmes

No props found

NCAAF Public Betting

Iowa State are 4-1 in their last 5 games.
Iowa State are 3-2 in their last 5 games against the spread
Iowa State are 1-3 in their road games against the spread
The totals have gone OVER in 2 of Iowa State' last 5 games
The totals have gone OVER in 3 of Iowa State' 5 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Iowa State	4-6	2-3	1-3	2-5	2-1
Kansas	4-6	2-4	2-2	3-3	1-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Iowa State	4-6	3-2	1-3	3-4	1-2
Kansas	5-5	3-3	2-2	3-3	2-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Iowa State	6-4	N/A	N/A	4-3	2-1
Kansas	5-5	N/A	N/A	4-2	0-3

date	opponent	score	spread	over/under	moneyline
Nov 8th	@TCU	W 20-17	+7.5 W	U 58	ISU +242
Nov 1st	ASU	L 19-24	-7.5 L	U 48.5	ASU -330
Oct 25th	BYU	L 27-41	-2.5 L	O 49	BYU -146
Oct 11th	@COLO	L 17-24	-3 L	U 52	COLO -154
Oct 4th	@CIN	L 30-38	+1.5 L	O 55.5	CIN +100

Total

Passing

2289

YDS

2303

185/289

Comps/Atts

183/305

7.92

YPA

7.55

21/4

TDs/INTs

12/9

18/169

Sacks/Yards

18/129

Rushing

1597

Rush Yards

1642

358

Attempts

380

4.46

YPC

4.32

14

TDs

20

Turnovers

Fumbles Lost

4

Interceptions

9

Efficiency

31/39 79.5%

Redzone

36/46 78.3%

44/125 0%

3rd Down

52/132 0%

16/25 0%

4th Down

13/21 0%

First Downs

205

Total

211

107

Pass

101

87

Rush

91

11

Penalty

19

Misc

/

Penalties/Yards

/

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MatchupOverUnder
Kansas 5-5	N/A	N/A
Iowa State 6-4	N/A	N/A