Kansas vs. Iowa State Odds & Betting Predictions - November 22, 2025

Kansas at Iowa State

5:00 pm • Fox Sports 1
14 - 38

Kansas at Iowa State Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Kansas
5-7
+3.5
+3.5-116
o55.5-109
+137
Iowa State
8-4
u53.5
-3.5-108
u55.5-110
-163
location pinSaturday 5:00 p.m.
November 22, 2025
Jack Trice StadiumAmes
Kansas vs. Iowa State Expert Picks
Duck
Duck
Last 30d: 212-153-4 (+27.7u)
KU +13.5 (Live)-110
1.1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 92-113-3 (-12.5u)
ISU -3.5-105
1.04u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 150-158-13 (+5.9u)
Over 55.5+105
0.7u
2.75% ev
KU +145 (1H)
0.8u
4.41% ev

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Prop Odds Comparison

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Line Movement Tracker

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Kansas vs. Iowa State Public Betting Percentages

Away Logo

Kansas

Public

56%

Bets%

44%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Iowa State
5-73-31-43-62-1
Kansas
5-73-42-33-32-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Iowa State
4-83-31-43-61-2
Kansas
5-73-42-33-32-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Iowa State
8-4N/AN/A6-32-1
Kansas
5-7N/AN/A4-20-5

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 8th@TCUW 20-17+7.5 WU 58ISU +242
Nov 1stASUL 19-24-7.5 LU 48.5ASU -330
Oct 25thBYUL 27-41-2.5 LO 49BYU -146
Oct 11th@COLOL 17-24-3 LU 52COLO -154
Oct 4th@CINL 30-38+1.5 LO 55.5CIN +100
Team Stats
323
Total Yards
462
50
Total Plays
73
6.46
Yards Per Play
6.328767123287672
191
YDS
241
16/29
Comps/Atts
18/23
6.586206896551724
YPA
10.478260869565217
1/1
TDs/INTs
3/0
0/0
Sacks/Yards
1/2
132
Rush Yards
221
21
Attempts
50
6.285714285714286
YPC
4.42
1
TDs
2
0
Fumbles Lost
0
1
Interceptions
0
1/3 33.33%
Redzone
4/4 100%
5/9 0%
3rd Down
9/16 0%
0/1 0%
4th Down
4/5 0%

First Downs

17
Total
25
10
Pass
13
6
Rush
11
1
Penalty
1
4/25
Penalties/Yards
3/30

Kansas vs. Iowa State Odds Comparison

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Kansas at Iowa State Team Totals

MatchupOverUnder
Kansas
5-7
o26.5-110
u26.5-110
Iowa State
8-4
o29.5-110
u29.5-115