- After crushing Illinois 63-10, No. 11 Indiana looks to remain undefeated as it travels to Iowa.
- Iowa is 1-0 in Big Ten play, with its lone loss this season coming to its rival Iowa State.
- Check out college football predictions below for the eight-point spread.
The Indiana Hoosiers take on the Iowa Hawkeyes in Iowa City, Iowa. Kickoff is set for 3:30 p.m. ET on Peacock.
Indiana is favored by -8 points on the spread with a moneyline of -300. Iowa, meanwhile, is a +8 underdog and comes in at +240 on the moneyline to pull off the upset. The over/under sits at 48 points.
Here’s my Indiana vs. Iowa prediction and college football picks for Saturday, September 27.
Indiana Hoosiers vs Iowa Hawkeyes Prediction, Picks
- Indiana vs. Iowa Pick: Indiana -8
My Iowa vs. Indiana best bet is on the Hoosiers to cover the spread. Find the best line available on our live NCAAF odds page.
Indiana vs Iowa Odds, Spread
| Indiana Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-9.5 -108 | 47.5 -110o / -110u | -325 |
| Iowa Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+9.5 -112 | 47.5 -110o / -110u | +270 |
- Indiana vs Iowa Spread: Indiana -9.5
- Indiana vs Iowa Over/Under: 47.5 Total Points
- Indiana vs Iowa Moneyline: Indiana ML -325
Indiana vs Iowa NCAAF Week 5 Preview
I love Indiana in this one, and I wouldn’t be shocked if it gets a little out of control.
In 10 drives against Rutgers, the Hawkeyes didn’t record a single methodical drive that went 10 plays.
That’s a big deal because if they can’t grind out those sustained possessions and they don't break off explosive plays, they're going to struggle, especially against a defense like Indiana’s that's also the top Havoc unit in the nation.
That gets amplified considering that Iowa runs a lot of inside zone. Indiana has a 67% Success Rate against that run concept while forcing a negative play 22% of the time.
Iowa also managed only two methodical drives in 10 possessions against Iowa State, so I don't expect it to all of a sudden figure it out against Curt Cignetti's team.
On the other side of the ball, Indiana runs inside zone with Roman Hemby and Kaelon Black. That's perfect against Iowa because the Hawkeyes have allowed a Success Rate of 39% against that run concept. They just can’t stop it.
That was Indiana's major advantage against Illinois, and then the Hoosiers went up there and put up 63 points. That edge isn't going anywhere here.
It's also worth noting that Indiana quarterback Fernando Mendoza has 14 touchdowns with no interceptions and just a single-turnover-worthy play against Old Dominion. That's bad news for an Iowa defense that ranks 98th in Finishing Drives allowed.
Indiana vs Iowa Week 5 College Football Pick
The line’s creeping up to around 8, but this might get ugly. I have got Indiana in a moneyline parlay alongside another favorite.
I'd also bet the Hoosiers to cover in what could be a grinding, messy game.
Pick: Indiana -8
