The South Florida Bulls take on the Memphis Tigers in Memphis, Tennessee. Kickoff is set for 12 p.m. ET on ESPN2.
USF is favored by 6 points on the spread with a moneyline of -220. The total is set at 58.5 points.
Here’s my USF vs. Memphis prediction and college football picks for Saturday, October 25.
USF Bulls vs Memphis Tigers Prediction, Picks
- USF vs. Memphis Pick: USF -4
My Memphis vs. USF best bet is on the Bulls to cover. Find the best line available on our live NCAAF odds page.
USF vs Memphis Odds, Line, Spread
| USF Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-4 -110 | 59.5 -108o / -112u | -185 |
| Memphis Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+4 -110 | 59.5 -108o / -112u | +154 |
- South Florida vs Memphis Spread: USF -4, Memphis +4
- South Florida vs Memphis Over/Under: 59.6
- South Florida vs Memphis Moneyline: USF ML -185, Memphis ML +154
USF vs Memphis NCAAF Week 9 Pick
This game triggered one of our Action PRO betting systems, powered by Evan Abrams.
The Right Favorite is a college football system built on recognizing when the betting market underestimates a favorite.
In the regular season, when an opponent is coming off a loss by seven to 23 points, perception often inflates their chances of rebounding. Yet, those weaknesses typically carry into the next game.
By focusing on contests where the total is set over 55, the system narrows in on higher-scoring games, making it more difficult for struggling teams to keep pace.
Limiting the sample to the first 11 games of the season ensures the analysis applies before postseason adjustments in motivation and preparation occur.
Finally, the spread filter targets situations where the line is set with the other side catching points, but not in extreme ranges, allowing favorites to deliver consistent covers.
Together, these conditions create a profile where the favorite is positioned as the stronger play despite public bias suggesting otherwise.
Teams that have fit this system are 13-7 ATS this year (65% win rate, 24% ROI). Five of the last six teams to fit this system have covered.
I could see the Tigers' struggles continuing after last week's horrific loss against UAB. Memphis' secondary is weak, allowing Ryder Burton to carve it up (20-for-27 passing, 240 yards, 3 TDs). I could see Byrum Brown having a similar week.
Meanwhile, Memphis has no idea who is starting at quarterback this week. Brendon Lewis left last week's game in the third quarter with a lower-body injury. Even if he plays, he might not be 100%, which would be a tremendous blow given that the entire offense is predicated on his dual-threat rushing ability.
Pick: USF -4
USF vs Memphis Betting Trends
