The NFL Divisional Round gets underway with a Saturday doubleheader, starting with Bills vs. Broncos at 4:30 p.m. ET (CBS) and concluding with 49ers vs. Seahawks at 8 p.m. ET (FOX).
NFL odds for Saturday list Denver as a 1-point spread favorite against Buffalo, and Seattle as a -7.5 favorite against San Francisco.
The sharpest NFL predictions for Saturday come via the Bills vs. Broncos spread; however, it's the 49ers vs. Seahawks over/under that's catching the eyes of the wiseguys in that matchup.
Below, we reveal two NFL predictions that professional bettors are making for Saturday's Divisional Round playoff matchups.
NFL Odds, 2 Sharp Predictions for Saturday
*Odds as of Friday afternoon
Bills vs. Broncos Prediction
Let's start with a Bills vs. Broncos spread prediction.














