| Ruben Loftus-Cheek | MID | Out | Heel Injury | Heel Injury | Jan 5 |
| Christian Pulisic | F | Out | Knock | Knock | Mar 4 |
| Mike Maignan | GK | Out | Suspended | Suspended | Aug 20 |
| Luka Modric | MID | Doubtful | None | Modric is doubtful | Dec 1 |
| Fikayo Tomori | DEF | Out | Knock | Knock | Jul 11 |
| Pervis Estupinan | DEF | Out | Hamstring | Hamstring | Apr 21 |
| Rafael Leao | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Oct 4 |
| Yacine Adli | MID | Out | Suspended | Suspended | Feb 28 |
| Strahinja Pavlovic | DEF | Out indefinitely | Knock | Knock | Sep 20 |
| Lorenzo Torriani | GK | Doubtful | Torriani, Lorenzo: doubtful - injured | Torriani is doubtful | Aug 22 |
| Ademola Lookman | F | Out indefinitely | Illness | Illness | Dec 27 |
| Sead Kolasinac | DEF | Out | Groin Strain | Groin Strain | Mar 31 |
| Lazar Samardzic | MID | Out indefinitely | Knee Injury | Knee Injury | Feb 21 |
| Kamaldeen Sulemana | F | Out | Ankle/Foot Injury | Ankle/Foot Injury | Nov 14 |
| Odilon Kossounou | DEF | Out indefinitely | None | Kossounou is injured | Feb 13 |
| Bacary Sagna | DEF | Out indefinitely | Groin Strain | Groin Strain | May 1 |
| Cheick Tidiane Diabaté | A | Out indefinitely | Groin/Pelvis Injury | Groin/Pelvis Injury | Jun 17 |
| Juan Miranda | DEF | Out indefinitely | Knock | Knock | Apr 11 |
| Emil Holm | DEF | Doubtful | Holm, Emil: doubtful - injured | Holm is doubtful | Aug 22 |
| V. Behrami | MID | Out indefinitely | Hamstring | Hamstring | Apr 17 |
| M. Balotelli | A | Out indefinitely | Knock | Knock | May 27 |
| Yerry Mina | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Nov 14 |
| Marko Rog | MID | Out indefinitely | None | Rog is injured | Feb 14 |
| Alberto Moreno | DEF | Out | Suspended | Suspended | Feb 18 |
| Alvaro Morata | F | Out indefinitely | Hamstring | Hamstring | Feb 14 |
| Alberto Cerri | F | Out indefinitely | None | Cerri is injured | May 22 |
| Antonio Sanabria | F | Out | Suspended | Suspended | Feb 4 |
| B. Adekanye | A | Out indefinitely | Hamstring | Hamstring | Dec 30 |
| David De Gea | GK | Out indefinitely | Knock | Knock | Apr 5 |
| Jonathan Ikone | MID | Out | Ankle Ligaments | Ankle Ligaments | Jan 3 |
| Moise Kean | F | Out | Suspended | Suspended | Sep 18 |
| Pablo Mari | DEF | Out | Ankle/Foot Injury | Ankle/Foot Injury | May 13 |
| Marin Pongracic | DEF | Out | Suspended | Suspended | Mar 6 |
| Abdelhamid Sabiri | MID | Out | Suspended | Suspended | Jun 16 |
| Christian Kouame | F | Out indefinitely | Kouame, Christian: missing - injured | Kouame is injured | Aug 22 |
| Mattia Viti | DEF | Out indefinitely | None | Viti is injured | Feb 13 |
| Aaron Martin | DEF | Out indefinitely | Groin Strain | Groin Strain | Sep 19 |
| Domagoj Bradaric | DEF | Out indefinitely | Ankle Ligaments | Ankle Ligaments | Feb 5 |
| Enzo Ebosse | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Sep 9 |
| Amin Sarr | F | Out | Thigh Muscle Strain | Thigh Muscle Strain | Apr 11 |
| Pedro | F | Out indefinitely | Shoulder Injury | Shoulder Injury | Sep 28 |
| Matteo Guendouzi | MID | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Jan 2 |
| Patric | DEF | Out indefinitely | Patric: missing - injured | Patric is injured | Aug 22 |
| Alessio Romagnoli | DEF | Suspended | Romagnoli, Alessio: missing - suspended | Romagnoli is suspended | Aug 22 |
| Samuel Gigot | DEF | Out | Ankle/Foot Injury | Ankle/Foot Injury | Mar 13 |
| Toma Basic | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | Mar 14 |
| Taty Castellanos | F | Out | Suspended | Suspended | Jan 14 |
| Lassana Coulibaly | MID | Out | Suspended | Suspended | May 24 |
| Frederic Guilbert | DEF | Out | Chest Injury | Chest Injury | Dec 12 |
| Tete Morente | F | Out indefinitely | Toe Injury | Toe Injury | Feb 16 |
| Remi Oudin | F | Out indefinitely | Virus | Virus | Jan 8 |
| Gaby Jean | DEF | Out indefinitely | Jean, Gaby: missing - injured | Jean is injured | Aug 22 |
| Nicolas Trabucchi | DEF | Doubtful | Trabucchi, Nicolas: doubtful - injured | Trabucchi is doubtful | Aug 22 |
| Mateus Lusuardi | DEF | Out indefinitely | Lusuardi, Mateus: missing - injured | Lusuardi is injured | Aug 22 |
| Lorenzo Pellegrini | MID | Out indefinitely | Pellegrini, Lorenzo: missing - injured | Pellegrini is injured | Aug 22 |
| Angelino | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Sep 13 |
| Leon Bailey | F | Out | Ankle/Foot Injury | Ankle/Foot Injury | May 15 |
| Zeki Celik | DEF | Out | Suspended | Suspended | Feb 20 |
| A. Tripaldelli | DEF | Out indefinitely | Knock | Knock | Nov 25 |
| Romelu Lukaku | F | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Sep 16 |
| Frank Anguissa | MID | Out | Suspended | Suspended | Feb 8 |
| Stanislav Lobotka | MID | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Dec 12 |
| Mathias Olivera | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Apr 4 |
| Armand Lauriente | F | Out | Back Injury | Back Injury | Nov 14 |
| Jeroen Zoet | GK | Out indefinitely | Knock | Knock | Oct 20 |
| Daniele Verde | MID | Out indefinitely | Hamstring | Hamstring | May 5 |
| Adam Masina | DEF | Out indefinitely | Knee Injury | Knee Injury | Dec 29 |
| Adrien Tameze | MID | Out | Back Injury | Back Injury | Oct 6 |
| Guillermo Maripan | DEF | Out | Thigh Muscle Strain | Thigh Muscle Strain | Mar 13 |
| Perr Schuurs | DEF | Out indefinitely | Knee Injury | Knee Injury | Jul 19 |
| Ardian Ismajli | DEF | Out indefinitely | Ismajli, Ardian: missing - injured | Ismajli is injured | Aug 22 |
| Zannetos Savva | MID | Doubtful | Savva, Zannetos: doubtful - injured | Savva is doubtful | Aug 22 |
| Alexis Sanchez | F | Out indefinitely | Knee Injury | Knee Injury | Apr 21 |
| Kingsley Ehizibue | DEF | Out indefinitely | Concussion | Concussion | Apr 17 |
Benevento Calcio
Brescia Calcio
FC Crotone
S.P.A.L. 2013
