49ers vs. Browns Odds & Betting Predictions - November 30, 2025

49ers at Browns

6:00 pm • CBS

San Francisco 49ers

@

Cleveland Browns

MatchupOpenSpreadTotalMoneyline
49ers 6-4	N/A	N/A	N/A
Browns 2-7	N/A	N/A	N/A

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Sunday 6:00 p.m.

November 30, 2025

Huntington Bank FieldCleveland

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NFL Public Betting

Browns are 1-4 in their last 5 games.
Browns are 2-3 in their last 5 games against the spread
Browns are 0-5 in their road games against the spread
The totals have gone OVER in 1 of Browns' last 5 games
The totals have gone OVER in 1 of Browns' 3 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Browns	3-6	3-0	0-5	1-1	2-5
49ers	5-5	1-3	4-2	3-2	2-3

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Browns	5-4	1-2	3-2	2-0	3-4
49ers	6-4	2-2	4-2	3-2	3-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Browns	2-7	N/A	N/A	1-1	1-6
49ers	6-4	N/A	N/A	4-1	2-3

date	opponent	score	spread	over/under	moneyline
Nov 9th	@NYJ	L 20-27	-2 L	O 37.5	NYJ -130
Oct 26th	@NE	L 13-32	+7 L	O 40.5	NE +275
Oct 19th	MIA	W 31-6	-2.5 W	O 34.5	CLE -142
Oct 12th	@PIT	L 9-23	+6.5 L	U 38	PIT +245
Oct 5th	MIN	L 17-21	+3.5 L	O 35.5	MIN +160

DeAndre Carter
WR
Carter is out with knee
Out
Mike Hall
DT
Hall is out with knee
Out
Isaiah Bond
WR
Bond is out with foot
Out

Brandon Aiyuk
WR
Aiyuk is out with knee
Out
Brock Purdy
QB
Purdy is out with toe
Out
Ricky Pearsall
WR
Pearsall is out with knee
Out
Jacob Cowing
WR
Cowing is out with hamstring
Out

Jordan James
RB
James is doubtful with finger
Doubtful

See more NFL Injuries

passing yards
-
815
pyds
passing touchdowns
Dillon Gabriel
5
ptd
rushing yards
Quinshon Judkins
486
ryds
rushing touchdowns
Quinshon Judkins
5
rtd

	Starter	2ND	3RD	4TH
QB	Dillon Gabriel	Shedeur Sanders	Deshaun Watson
RB	Jerome Ford	Quinshon Judkins	Dylan Sampson
WR	Jamari Thrash	DeAndre Carter	Gage Larvadain
TE	David Njoku	Harold Fannin	Blake Whiteheart	Brenden Bates	Sal Cannella
LT	Dawand Jones	Cornelius Lucas
LG	Joel Bitonio	Teven Jenkins
C	Ethan Pocic	Luke Wypler
RG	Wyatt Teller	Zak Zinter
RT	Jack Conklin
LDE	Alex Wright	Isaiah McGuire	Julian Okwara
RDE	Myles Garrett	Cameron Thomas
WLB	Devin Bush	Jerome Baker	Winston Reid
MLB	Carson Schwesinger	Mohamoud Diabate	Easton Mascarenas-Arnold
LCB	Denzel Ward	Dom Jones
SS	Grant Delpit	Rayshawn Jenkins	Donovan McMillon
FS	Ronnie Hickman	Christopher Edmonds
P	Corey Bojorquez
H	Corey Bojorquez
PR	DeAndre Carter	Gage Larvadain	Kaden Davis
KR	DeAndre Carter	Kaden Davis
LS	Rex Sunahara
RWR	Jerry Jeudy	Isaiah Bond	Kaden Davis
NT	Maliek Collins	Shelby Harris	Adin Huntington
LWR	Cedric Tillman
DT	Mason Graham	Mike Hall	Sam Kamara
NB	Myles Harden
K	Andre Szmyt

Total

Passing

2295

YDS

1392

216/323

Comps/Atts

178/302

7.486

YPA

5.023

14/9

TDs/INTs

7/8

18/123

Sacks/Yards

20/125

Rushing

874

Rush Yards

716

249

Attempts

190

3.51

YPC

3.768

5

TDs

6

Turnovers

Fumbles Lost

9

Interceptions

8

Efficiency

17/30 56.67%

Redzone

12/21 57.14%

57/121 0%

3rd Down

38/115 0%

7/12 0%

4th Down

11/19 0%

First Downs

192

Total

134

123

Pass

70

55

Rush

47

14

Penalty

17

Misc

/

Penalties/Yards

/

Possession

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MatchupOverUnder
49ers 6-4	N/A	N/A
Browns 2-7	N/A	N/A