Astros vs. Cubs Odds & Betting Predictions - May 23, 2026
Astros at Cubs
6:20 pm • MARQStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
 |  | 4.86 | 7-7 | |
 |  | 4.35 | 5-6 |
Astros at Cubs Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Astros 52-54 | +1.5 | +1.5-179 | o7-113 | +125 |
Cubs 59-45 | u7.5 | -1.5+151 | u7-105 | -149 |
Wrigley FieldChicago
Astros vs. Cubs Expert Picks
Wags Wins
Last 30d: 182-174-4 (-10.1u)
HOU +135
1.35u
Frank Ammirante
Last 30d: 323-378-8 (-55.1u)
C.Rea o4.5 Ks+103
0.97u
Under 3.5 (F5)+110
1u
K.Teng u3.5 Hits Allowed+120
1u
Brian Bitler
Last 30d: 49-66-1 (-47.6u)
HOU +138
4.14u
Doug Ziefel
Last 30d: 96-100-1 (+6.7u)
C.Rea u17.5 Outs-105
0.53u
Under 7.5-115
0.5u
Sean Zerillo
Last 30d: 114-138-10 (-11.2u)
Under 7.5-115
0.5u
Bet to 7 (-110)
Adam Kaufman
Last 30d: 114-102-1 (+9.8u)
HOU +130
1.3u
Nick Martin
Last 30d: 9-11-1 (-2.6u)
CHC -140
1u
Astros vs. Cubs Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Astros vs. Cubs Public Betting Percentages
Betting Trends
- Cubs are 3-2 in their last 5 games.
- Cubs are 3-2 in their last 5 games against the spread
- Cubs are 27-26 in their road games against the spread
- The totals have gone OVER in 3 of Cubs' last 5 games
- The totals have gone OVER in 28 of Cubs' 52 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Astros vs. Cubs Injury Updates
Astros Injuries
Cubs Injuries
- Tyler Austin1B
Austin is out with knee
Out
- Justin SteeleSP
Steele is out with elbow
Out
Astros vs. Cubs Box Score
Astros Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
 | 89 | 6 | 6 | 0 | |
 | 11 | 1 | 1 | 0 | |
 | 8 | 1 | 1 | 0 | |
 | 21 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
 | 0-4 | 0 | 0 | 0 |
 | 1-3 | 0 | 0 | 0 |
 | 0-2 | 1 | 0 | 0 |
 | 0-1 | 0 | 0 | 0 |
| 0-1 | 0 | 0 | 0 |
 | 3-3 | 2 | 2 | 3 |
 | 0-4 | 0 | 0 | 0 |
 | 0-0 | 0 | 0 | 0 |
 | 1-4 | 0 | 0 | 0 |
 | 0-3 | 0 | 0 | 0 |
 | 0-0 | 0 | 0 | 0 |
 | 1-4 | 0 | 0 | 0 |
| 1-4 | 0 | 0 | 0 |
| 1-4 | 0 | 0 | 0 |
 | 0-3 | 0 | 0 | 0 |
Cubs Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
 | 98 | 7 | 4 | 3 | |
 | 14 | 1 | 0 | 0 | |
 | 16 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
 | 1-4 | 0 | 0 | 0 |
 | 1-4 | 0 | 0 | 0 |
 | 0-4 | 0 | 0 | 0 |
 | 0-2 | 0 | 0 | 0 |
 | 0-2 | 0 | 0 | 0 |
 | 0-1 | 0 | 0 | 0 |
| 0-1 | 0 | 0 | 0 |
 | 0-3 | 0 | 0 | 0 |
 | 0-1 | 0 | 0 | 0 |
 | 0-2 | 0 | 0 | 0 |
 | 0-1 | 0 | 0 | 0 |
 | 0-0 | 0 | 0 | 0 |
 | 1-3 | 0 | 0 | 0 |
Astros vs. Cubs Odds Comparison
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Astros at Cubs Team Totals
MatchupOverUnder | ||
|---|---|---|
Astros 52-54 | N/A | N/A |
Cubs 59-45 | N/A | N/A |