Astros vs. Cubs Odds & Betting Predictions - May 23, 2026

Astros at Cubs

6:20 pm • MARQ

Houston Astros

38-43

3 - 0

Chicago Cubs

41-37

pitcher		team	era	w-l
C.Rea			4.99	5-5
K.Teng			4.03	4-6

MatchupOpenSpreadTotalMoneyline
Astros 38-43	+1.5	+1.5-179	o7-113	+125
Cubs 41-37	u7.5	-1.5+151	u7-105	-149

Saturday 6:20 p.m.

May 23, 2026

Wrigley FieldChicago

HOU +135

1.35u

C.Rea o4.5 Ks+103

0.97u

Under 3.5 (F5)+110

K.Teng u3.5 Hits Allowed+120

HOU +138

4.14u

C.Rea u17.5 Outs-105

0.53u

Under 7.5-115

0.5u

Under 7.5-115

0.5u

Bet to 7 (-110)

HOU +130

1.3u

CHC -140

The Leadoff: Trollo's MLB Breakdown and Bets for Saturday
Matt Trollo•
May 23, 2026 UTC
Minion's +351 SGP for Astros vs Cubs
Ryan Minion•
May 23, 2026 UTC

See more MLB Coverage

No props found

MLB Public Betting

Cubs are 3-2 in their last 5 games.
Cubs are 3-2 in their last 5 games against the spread
Cubs are 16-22 in their road games against the spread
The totals have gone OVER in 4 of Cubs' last 5 games
The totals have gone OVER in 21 of Cubs' 40 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cubs	30-48	14-26	16-22	20-34	10-14
Astros	38-43	19-22	19-21	8-18	29-24

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cubs	41-37	21-19	20-18	27-27	14-10
Astros	42-35-4	24-16-1	18-19-3	15-11	26-23-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cubs	41-37	23-17	18-20	30-24	11-13
Astros	38-43	20-21	18-22	11-15	26-27

date	opponent	score	spread	over/under	moneyline
May 22nd	HOU	L 2-4	-1.5 L	U 7	HOU -149
May 20th	MIL	L 0-5	+1.5 L	U 6.5	MIL -112
May 19th	MIL	L 2-5	+1.5 L	U 7.5	MIL +103
May 18th	MIL	L 3-9	-1.5 L	O 10.5	MIL -161
May 17th	@CWS	L 8-9	-1.5 L	O 9	CWS -131

Lance McCullers
SP
Lance McCullers Jr. has been scratched Tuesday. Jason Alexander will start.
Out

Tyler Austin
1B
Austin is out with knee
Out
Justin Steele
SP
Steele is out with elbow
Out

See more MLB Injuries

PITCHER	PC	IP	K
RK.Teng, P	89	6	6
LS.Okert, P	11	1	1
RE.De Los Santos, P	8	1	1
LB.King, P	21	1	1

HITTERS	H-AB	R	HR	RBI
1J.Pena, SS	0-4	0	0	0
2I.Paredes, 3B	1-3	0	0	0
3Y.Alvarez, DH	0-2	1	0	0
3Z.Dezenzo, PH	0-1	0	0	0
3Z.Dezenzo, DH	0-1	0	0	0
4C.Walker, 1B	3-3	2	2	3
5B.Shewmake, 2B	0-4	0	0	0
5J.Meyers, CF	0-0	0	0	0
6C.Smith, RF	1-4	0	0	0
7Z.Cole, LF	0-3	0	0	0
7N.Allen, 2B	0-0	0	0	0
8B.Matthews, CF	1-4	0	0	0
8B.Matthews, 2B	1-4	0	0	0
8B.Matthews, LF	1-4	0	0	0
9C.Salazar, C	0-3	0	0	0

PITCHER	PC	IP	K	ER
RC.Rea, P	98	7	4	3
RT.Thornton, P	14	1	0	0
LR.Rolison, P	16	1	1	0

HITTERS	H-AB	R	HR	RBI
1P.Crow-Armstrong, CF	1-4	0	0	0
2A.Bregman, 3B	1-4	0	0	0
3M.Busch, 1B	0-4	0	0	0
4N.Hoerner, 2B	0-2	0	0	0
5M.Conforto, LF	0-2	0	0	0
5K.Alcantara, PH	0-1	0	0	0
5K.Alcantara, LF	0-1	0	0	0
6S.Suzuki, RF	0-3	0	0	0
7M.Ballesteros, DH	0-1	0	0	0
8M.Amaya, C	0-2	0	0	0
8P.Ramirez, PH	0-1	0	0	0
8C.Kelly, C	0-0	0	0	0
9D.Swanson, SS	1-3	0	0	0