Cubs vs. Guardians Odds & Betting Predictions - April 5, 2026
Cubs at Guardians
8:40 pm • MARQStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
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Cubs at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Cubs 3-4 | -1.5 | -1.5+130 | o7.5-110 | -130 |
Guardians 5-3 | u7 | +1.5-155 | u7.5-110 | +110 |

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Cubs vs. Guardians Expert Picks
OldSchool0909
Last 30d: 104-112-1 (-11.6u)
CLE +108
1u
Prop Odds Comparison
Line Movement Tracker
Cubs vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 3-2 in their last 5 games.
- Guardians are 3-2 in their last 5 games against the spread
- Guardians are 4-3 in their road games against the spread
- The totals have gone OVER in 1 of Guardians' last 5 games
- The totals have gone OVER in 0 of Guardians' 1 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Cubs Injury Updates

Guardians Injuries

Cubs Injuries
- Tyler Austin1B
Austin is out with knee
Out
- Justin SteeleSP
Steele is out with elbow
Out
- Jordan WicksSP
Wicks is out with arm
Out
- Seiya SuzukiRF
Suzuki is out with knee
Out
Cubs vs. Guardians Odds Comparison
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Cubs at Guardians Team Totals
MatchupOverUnder | ||
|---|---|---|
Cubs 3-4 | N/A | N/A |
Guardians 5-3 | N/A | N/A |


