Cubs vs. Pirates Odds & Betting Predictions - May 25, 2026

Cubs at Pirates

5:35 pm • SportsNet PT
1 - 1

Cubs at Pirates Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
29-24
-1.5
-1.5+134
o8.5-109
-124
Pirates
27-26
u8
+1.5-162
u8.5-110
+103
location pinMonday 5:35 p.m.
May 25, 2026
PNC ParkPittsburgh
Cubs vs. Pirates Expert Picks
Wags Wins
Wags Wins
Last 30d: 223-297-5 (-94.5u)
CHC -125
2u
OldSchool0909
Last 30d: 57-67-0 (-1.7u)
PIT +113
1u
Ryan Minion
Ryan Minion
Last 30d: 339-366-16 (+6.5u)
P.Crow-Armstrong o1.5 Total Bases+120
$1.00
CHC -125
$1.25
Frank Ammirante
Frank Ammirante
Last 30d: 239-263-10 (-10.0u)
B.Brown o5.5 Ks+121
0.83u
Adam Kaufman
Adam Kaufman
Last 30d: 41-49-0 (-13.2u)
PIT -104
1.04u
Sean Zerillo
Sean Zerillo
Last 30d: 175-145-12 (+6.1u)
CHC -110
0.55u
Bet to -120

Cubs vs. Pirates Previews & Analysis

  • The Leadoff: Anderson's MLB Breakdown & Bets for Monday article feature image

    The Leadoff: Anderson's MLB Breakdown & Bets for Monday

    Jon Anderson
    May 25, 2026 UTC
  • Zerillo's Projection for Cubs-Pirates article feature image

    Zerillo's Projection for Cubs-Pirates

    Tanner McGrath
    May 25, 2026 UTC
  • +300, +470, +520 Data Model HR Picks article feature image

    +300, +470, +520 Data Model HR Picks

    Alex Kolodziej
    May 25, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. Pirates Public Betting Percentages

Away Logo

Cubs

Public

58%

Bets%

42%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Pirates
28-2513-1315-1216-1311-12
Cubs
21-3212-179-1514-217-11

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Pirates
27-24-216-1011-14-217-129-12-2
Cubs
29-2415-1414-1018-1711-7

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Pirates
27-2613-1314-1317-129-14
Cubs
29-2418-1111-1321-148-10

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 24th@TORW 4-1+1.5 WU 7.5PIT +145
May 23rd@TORL 2-5-1.5 LU 7.5TOR -144
May 22nd@TORL 2-6+1.5 LU 8TOR +137
May 21st@STLW 6-2-1.5 WO 7PIT -121
May 20th@STLW 7-0-1.5 WU 7.5PIT -103

Pirates vs. Cubs Injury Updates

Pirates Injuries

  • Jared Jones
    SP

    Jones is out with elbow

    Out

Cubs Injuries

  • Tyler Austin
    1B

    Austin is out with knee

    Out

  • Justin Steele
    SP

    Steele is out with elbow

    Out

  • Jordan Wicks
    SP

    Wicks is out with arm

    Out

Cubs vs. Pirates Box Score
Cubs Player Stats
Projected
PITCHERPCIPKER
Ben Brown logoRB.Brown, P83671
HITTERSH-ABRHRRBI
Pete Crow-Armstrong logo1P.Crow-Armstrong, CF0-4000
Ian Happ logo2I.Happ, LF0-2000
Michael Busch logo3M.Busch, 1B1-3111
Alex Bregman logo4A.Bregman, 3B2-3000
Michael Conforto logo5M.Conforto, RF0-3000
Pedro Ramirez logo6P.Ramirez, 2B1-3000
Moises Ballesteros logo7M.Ballesteros, DH2-2000
Miguel Amaya logo8M.Amaya, C0-2000
Dansby Swanson logo9D.Swanson, SS0-3000
Pirates Player Stats
Projected
PITCHERPCIPKER
Carmen Mlodzinski logoRC.Mlodzinski, P86521
Wilber Dotel logoRW.Dotel, P261.210
HITTERSH-ABRHRRBI
Spencer Horwitz logo1S.Horwitz, 1B1-2100
Brandon Lowe logo2B.Lowe, 2B2-3001
Bryan Reynolds logo3B.Reynolds, RF0-3000
Nick Gonzales logo4N.Gonzales, 3B0-3000
Oneil Cruz logo5O.Cruz, CF1-3000
Marcell Ozuna logo6M.Ozuna, DH0-3000
Konnor Griffin logo7K.Griffin, SS0-1000
Jhostynxon Garcia logo8J.Garcia, LF0-2000
Henry Davis logo9H.Davis, C0-2000

Cubs vs. Pirates Odds Comparison

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Cubs at Pirates Team Totals

MatchupOverUnder
Cubs
29-24
N/A
N/A
Pirates
27-26
N/A
N/A