Cubs vs. White Sox Odds & Betting Predictions - May 16, 2026

Cubs at White Sox

11:10 pm • MARQ
3 - 8
Starting Pitchers
pitcherteameraw-l
Davis Martin logoD.MartinChicago White Sox logo3.189-3
Jameson Taillon logoJ.TaillonChicago Cubs logo5.192-5

Cubs at White Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
41-37
+1.5
-1.5+165
o8.5-112
-108
White Sox
41-37
u8.5
+1.5-176
u8.5-107
-110
location pinSaturday 11:10 p.m.
May 16, 2026
Rate FieldChicago
Cubs vs. White Sox Expert Picks
Player Prop Savant
Player Prop Savant
Last 30d: 100-67-0 (+29.4u)
CHC +5.5 (Live)-135
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 86-122-3 (-14.7u)
Over 8.5-110
1u
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 7-12-2 (-3.7u)
Under 4.5 (F5)-109
0.84u
#EV 1.55%
Mike McNamara
Mike McNamara
Last 30d: 48-69-3 (+2.2u)
CWS -110
0.1u
Grant Neiffer
Grant Neiffer
Last 30d: 35-117-3 (+7.6u)
M.Vargas o0.5 HR+464
1.16u
RoyalsProps
RoyalsProps
Last 30d: 57-58-0 (-10.1u)
C.Montgomery o1.5 Hits + Runs + RBIs-108
1u
Frank Ammirante
Frank Ammirante
Last 30d: 320-265-11 (+57.1u)
M.Murakami o0.5 HR+290
0.29u
CWS -120 (F5)
1u

Cubs vs. White Sox Previews & Analysis

  • Grant's 2 Best Home Run Bets for Saturday article feature image

    Grant's 2 Best Home Run Bets for Saturday

    Grant Neiffer
    May 16, 2026 UTC
  • The Leadoff: Trollo's MLB Breakdown & Bets for Saturday article feature image

    The Leadoff: Trollo's MLB Breakdown & Bets for Saturday

    Matt Trollo
    May 16, 2026 UTC
  • Cubs vs White Sox: PRO's Prop Edge for Saturday article feature image

    Cubs vs White Sox: PRO's Prop Edge for Saturday

    Action Network Staff
    May 16, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. White Sox Public Betting Percentages

Away Logo

Cubs

Public

54%

Bets%

46%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
White Sox
45-3326-1219-217-537-28
Cubs
30-4814-2616-2220-3410-14

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
White Sox
45-32-121-16-124-166-5-138-27
Cubs
41-3721-1920-1827-2714-10

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
White Sox
41-3726-1215-258-432-33
Cubs
41-3723-1718-2030-2411-13

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 15thCHCL 5-10+1.5 LO 8.5CHC +106
May 14thKCW 6-2+1.5 WO 7.5CWS +114
May 13thKCW 6-5+1.5 WO 8CWS -105
May 12thKCW 6-5+1.5 WO 9.5CWS -105
May 10thSEAW 2-1+1.5 WU 8CWS +118

White Sox vs. Cubs Injury Updates

White Sox Injuries

  • Mike Vasil
    RP

    Vasil is out with elbow

    Out

  • Ky Bush
    SP

    Bush is out with elbow

    Out

  • Brooks Baldwin
    LF

    Baldwin is out with elbow

    Out

  • Drew Thorpe
    SP

    Thorpe is out with elbow

    Out

Cubs Injuries

  • Tyler Austin
    1B

    Austin is out with knee

    Out

  • Justin Steele
    SP

    Steele is out with elbow

    Out

Cubs vs. White Sox Box Score
Cubs Player Stats
Projected
PITCHERPCIPKER
Jameson Taillon logoRJ.Taillon, P90528
Ethan Roberts logoRE.Roberts, P31230
Ryan Rolison logoLR.Rolison, P12110
HITTERSH-ABRHRRBI
Nico Hoerner logo1N.Hoerner, SS1-5000
Michael Busch logo2M.Busch, 1B1-4000
Alex Bregman logo3A.Bregman, 3B2-4000
Ian Happ logo4I.Happ, DH0-4000
Seiya Suzuki logo5S.Suzuki, RF0-4000
Michael Conforto logo6M.Conforto, LF1-3100
Matt Shaw logo7M.Shaw, 2B0-4000
Pete Crow-Armstrong logo8P.Crow-Armstrong, CF1-3112
Miguel Amaya logo9M.Amaya, C2-4111
White Sox Player Stats
Projected
PITCHERPCIPKER
Davis Martin logoRD.Martin, P91671
Brandon Eisert logoLB.Eisert, P31100
Trevor Richards logoRT.Richards, P34222
HITTERSH-ABRHRRBI
Sam Antonacci logo1S.Antonacci, LF2-4200
Munetaka Murakami logo2M.Murakami, 1B2-3323
Miguel Vargas logo3M.Vargas, 3B1-4113
Colson Montgomery logo4C.Montgomery, SS1-4111
Chase Meidroth logo5C.Meidroth, 2B0-4000
Andrew Benintendi logo6A.Benintendi, DH2-3111
Randal Grichuk logo6R.Grichuk, PH0-1000
Randal Grichuk logo6R.Grichuk, DH0-1000
Jarred Kelenic logo7J.Kelenic, RF0-3000
Tristan Peters logo8T.Peters, CF0-2000
Drew Romo logo9D.Romo, C0-3000

Cubs vs. White Sox Odds Comparison

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Cubs at White Sox Team Totals

MatchupOverUnder
Cubs
41-37
N/A
N/A
White Sox
41-37
N/A
N/A