Diamondbacks vs. Cardinals Odds & Betting Predictions - May 24, 2025

Diamondbacks at Cardinals

12:15 am • Apple TV+

Arizona Diamondbacks

51-59

3 - 4

St. Louis Cardinals

55-56

pitcher		team	era	w-l
M.Mikolas			4.83	6-8
Z.Gallen			5.60	7-12

MatchupOpenSpreadTotalMoneyline
Diamondbacks 51-59	-1.5	-1.5+145	o8-116	-118
Cardinals 55-56	u8.5	+1.5-175	u8-102	-102

Saturday 12:15 a.m.

May 24, 2025

Busch StadiumSt. Louis

ARI -120

1.25u

Over 8.5-110

D-backs' ace Gallen reeling – 5.14 ERA, 10 HRs allowed in 10 starts. Cardinals offense thrives at home – .287 AVG, 16-8 record, 3rd in league batting. STL scored 5+ in 8 of last 14. Gallen gave up 6 runs, 4 HRs in his last start – struggles continue. Cards 7th in runs, lineup clicking behind Nootbaar. Arizona offense potent too – 5th in runs (5.12/game), 8th in AVG (.254), 1st in doubles, 4th in HRs. D-backs hitting .269 in May. Mikolas reliable lately but home ERA 4.70, vulnerable if pitch count climbs. Over trend strong: Over is 8-3 in last 11 D-backs/Cards games at Busch Stadium. Both lineups pack power and speed – expect traffic on bases. Two lineups with firepower, shaky starting pitching outlook. High-scoring battle very likely.

ARI o4.5 Team Total-110

1.1u

ARI o4.5 Team Total-110

1.1u

Under 8.5+105

0.53u

Bet to -105

Under 8.5-115

0.87u

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ARI -0.5 (F5)+100

1.5u

Over 8.5-105

0.25u

Diamondbacks vs. Cardinals: +268 SGP for Friday
Nick Martin•
May 23, 2025 UTC

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No props found

MLB Public Betting

Cardinals are 1-4 in their last 5 games.
Cardinals are 1-4 in their last 5 games against the spread
Cardinals are 27-28 in their road games against the spread
The totals have gone OVER in 1 of Cardinals' last 5 games
The totals have gone OVER in 29 of Cardinals' 56 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	57-54	30-26	27-28	22-31	34-23
Diamondbacks	50-59	24-30	26-29	28-40	22-19

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	55-50-6	29-24-3	26-26-3	26-22-5	28-28-1
Diamondbacks	54-50-5	26-24-4	28-26-1	34-30-4	20-20-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	55-56	32-24	23-32	27-26	27-30
Diamondbacks	51-59	26-28	25-30	34-34	17-24

date	opponent	score	spread	over/under	moneyline
May 21st	DET	L 1-5	+1.5 L	U 9	DET -116
May 20th	DET	L 4-5	+1.5 W	O 7.5	DET +150
May 19th	DET	W 11-4	-1.5 W	O 8	STL -166
May 18th	@KC	L 1-2	-1.5 L	U 8	KC -115
May 17th	@KC	W 1-0	-1.5 L	U 9	STL -104

Nolan Arenado
3B
Arenado is out with shoulder
Out

John Curtiss
RP
Curtiss is out with elbow
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
RZ.Gallen, P	100	5.2	4	4
RJ.Morillo, P	3	0.1	1	0
RS.McGough, P	4	1	0	0
RR.Thompson, P	8	1	0	0

HITTERS	H-AB	R	HR	RBI
1C.Carroll, RF	0-5	0	0	0
2K.Marte, 2B	1-4	1	1	1
3L.Gurriel, LF	2-4	0	0	0
4J.Naylor, 1B	1-4	0	0	0
5E.Suarez, 3B	1-4	0	0	0
6P.Smith, DH	0-2	0	0	0
6R.Grichuk, PH	1-2	1	0	0
6R.Grichuk, DH	1-2	1	0	0
7G.Perdomo, SS	0-4	0	0	0
8A.Thomas, CF	0-2	0	0	0
8T.Tawa, PH	1-2	0	0	0
8T.Tawa, CF	1-2	0	0	0
9J.Herrera, C	0-1	0	0	0
9G.Moreno, PH	1-1	1	1	2

PITCHER	PC	IP	K	ER
RM.Mikolas, P	81	6	4	1
LJ.Romero, P	21	1	0	0
RK.Leahy, P	11	1	0	0
RR.Helsley, P	22	1	1	2

HITTERS	H-AB	R	RBI
1L.Nootbaar, RF	0-3	1	0
1L.Nootbaar, LF	0-3	1	0
2M.Winn, SS	1-3	0	0
3B.Donovan, LF	0-1	1	0
3B.Donovan, 2B	0-1	1	0
4I.Herrera, DH	0-3	1	1
5A.Burleson, 1B	0-3	0	0
6N.Arenado, 3B	1-3	0	3
7N.Gorman, 2B	0-3	0	0
7J.Walker, RF	0-0	0	0
8P.Pages, C	0-3	0	0
9V.Scott, CF	2-3	1	0