Giants vs. Cardinals Odds & Betting Predictions - September 6, 2025

Giants at Cardinals

11:15 pm • FOX

San Francisco Giants

2

2 - 3

St. Louis Cardinals

3

pitcher		team	era	w-l
A.Pallante			5.38	6-13
J.Verlander			4.29	3-10

MatchupOpenSpreadTotalMoneyline
Giants 72-70	-1.5	-1.5+135	o8.5-106	-122
Cardinals 71-72	u8.5	+1.5-164	u8.5-112	+102

location pin

Saturday 11:15 p.m.

September 06, 2025

Busch StadiumSt. Louis

SF -122

0.61u

No props found

MLB Public Betting

Cardinals are 3-2 in their last 5 games.
Cardinals are 3-2 in their last 5 games against the spread
Cardinals are 35-34 in their road games against the spread
The totals have gone OVER in 2 of Cardinals' last 5 games
The totals have gone OVER in 37 of Cardinals' 74 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	72-71	37-37	35-34	25-39	46-32
Giants	65-77	29-40	36-37	31-52	33-24

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	72-64-7	37-34-3	35-30-4	32-27-5	39-37-2
Giants	66-71-5	28-40-1	38-31-4	30-52-1	34-19-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	71-72	40-34	31-38	32-32	38-40
Giants	72-70	35-34	37-36	44-39	27-30

date	opponent	score	spread	over/under	moneyline
Sep 6th	SF	L 2-8	+1.5 L	O 8.5	SF -122
Sep 3rd	ATH	W 5-1	+1.5 W	U 8.5	STL -111
Sep 2nd	ATH	W 2-1	+1.5 W	U 8.5	STL -108
Sep 1st	ATH	L 3-11	-1.5 L	O 7.5	ATH -158
Aug 31st	@CIN	L 4-7	+1.5 L	O 8.5	CIN +116

Nolan Arenado
3B
Arenado is out with shoulder
Out
Brendan Donovan
2B
Donovan is out with groin
Out

Tom Murphy
C
Murphy is out with back
Out
JT Brubaker
RP
Brubaker is out with ribs
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
RJ.Verlander, P		88	6	6	0
LJ.Lucchesi, P		17	1.2	1	0
RJ.Butto, P		4	0.1	0	0
RR.Walker, P		16	0	0	3

HITTERS	H-AB	R	HR	RBI
1J.Lee, CF	2-4	0	0	0
2R.Devers, 1B	0-3	0	0	0
3W.Adames, SS	0-3	0	0	0
4D.Smith, DH	2-4	1	0	0
5M.Chapman, 3B	2-3	1	0	0
6C.Schmitt, 2B	0-3	0	0	1
7D.Gilbert, RF	1-4	0	0	1
8L.Matos, LF	0-4	0	0	0
9P.Bailey, C	0-3	0	0	0

PITCHER		PC	IP	K	ER
RA.Pallante, P		89	6	3	2
RK.Leahy, P		22	2	1	0
RR.O'Brien, P		8	1	1	0

HITTERS	H-AB	R	HR	RBI
1L.Nootbaar, LF	1-4	0	0	0
2I.Herrera, DH	0-4	0	0	0
3N.Gorman, 1B	1-4	1	0	0
4M.Winn, SS	1-3	1	0	0
5J.Crooks, C	0-3	0	0	0
5G.Hampson, PR	0-0	1	0	0
6T.Saggese, 2B	1-4	0	0	1
7J.Walker, RF	1-4	0	0	2
8V.Scott, CF	1-3	0	0	0
9J.Fermin, 3B	1-2	0	0	0

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MatchupOverUnder
Giants 72-70	N/A	N/A
Cardinals 71-72	N/A	N/A