Guardians vs. Phillies Odds & Betting Predictions - May 22, 2026

Guardians at Phillies

10:40 pm • NBCS-PH

Cleveland Guardians

41-39

1 - 0

Philadelphia Phillies

43-36

pitcher		team	era	w-l
C.Sanchez			1.80	9-3
G.Williams			3.82	9-4

MatchupOpenSpreadTotalMoneyline
Guardians 41-39	+1.5	+1.5-156	o6.5-114	+154
Phillies 43-36	u7.5	-1.5+130	u6.5-103	-185

Friday 10:40 p.m.

May 22, 2026

Citizens Bank ParkPhiladelphia

Under 6.5+100

Under 3.5 (F5)-110

0.5u

Under 7-110

0.91u

@Zerillo ⭐️⭐️⭐️ https://myaction.app/mcSZfWMQl3b

PHI -178

@Zerillo ⭐️⭐️⭐️ https://myaction.app/mcSZfWMQl3b

Under 7.5-160

0.31u

Under 7.5-155

CLE +158

1.58u

Under 7-110

0.5u

Bet to 6.5 (-110)

PHI -175

1.75u

C. Sanchez

PHI -175

0.88u

Bet to -200

Adam Trigger's Triple-A Baseball Picks for Friday
Adam Trigger•
May 22, 2026 UTC
Guardians vs Phillies: Feltman's F5 Pick for Friday
John Feltman•
May 22, 2026 UTC

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No props found

MLB Public Betting

Phillies are 2-3 in their last 5 games.
Phillies are 2-3 in their last 5 games against the spread
Phillies are 13-23 in their road games against the spread
The totals have gone OVER in 2 of Phillies' last 5 games
The totals have gone OVER in 21 of Phillies' 42 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Phillies	28-50	15-27	13-23	23-33	5-17
Guardians	42-37	19-17	23-20	18-23	24-13

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Phillies	33-42-3	21-19-2	12-23-1	27-27-2	6-15-1
Guardians	39-40	18-18	21-22	21-20	17-20

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Phillies	42-36	23-19	19-17	34-22	8-14
Guardians	41-38	19-17	22-21	22-19	19-18

date	opponent	score	spread	over/under	moneyline
May 20th	CIN	L 4-9	-1.5 L	O 9.5	CIN -154
May 19th	CIN	L 1-4	-1.5 L	U 8.5	CIN -141
May 18th	CIN	W 5-4	-1.5 L	U 10	PHI -125
May 17th	@PIT	W 6-0	-5.5 W	U 7	PHI +110
May 16th	@PIT	W 6-0	-1.5 W	U 8.5	PHI -182

Kyle Schwarber
DH
Kyle Schwarber scratched Tuesday.
Out
Max Lazar
RP
Lazar is out with oblique
Out

Andrew Painter
SP
Andrew Painter was seen walking out to bullpen, he won't start but could be available in relief.
Questionable

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PITCHER		PC	IP	K	ER
RG.Williams, P		99	8	11	0
RC.Smith, P		8	1	1	0

HITTERS	H-AB	R	HR	RBI
1A.Martinez, RF	0-4	0	0	0
2J.Ramirez, 3B	1-4	0	0	0
3R.Hoskins, 1B	0-2	0	0	0
3K.Manzardo, PH	1-1	1	1	1
3K.Manzardo, 1B	1-1	1	1	1
4D.Fry, DH	2-3	0	0	0
4C.DeLauter, PH	0-1	0	0	0
4C.DeLauter, DH	0-1	0	0	0
5T.Bazzana, 2B	0-4	0	0	0
6B.Rocchio, SS	1-3	0	0	0
7S.Kwan, LF	0-3	0	0	0
8A.Hedges, C	1-2	0	0	0
9P.Halpin, CF	0-3	0	0	0

PITCHER		PC	IP	K	ER
LC.Sanchez, P		96	8	6	0
RJ.Duran, P		14	1	1	1

HITTERS	H-AB	R	HR	RBI
1T.Turner, SS	0-4	0	0	0
2K.Schwarber, DH	0-4	0	0	0
3B.Harper, 1B	1-4	0	0	0
4A.Bohm, 3B	0-3	0	0	0
5B.Marsh, LF	1-3	0	0	0
6A.Garcia, RF	0-3	0	0	0
7B.Stott, 2B	1-3	0	0	0
8J.Realmuto, C	1-3	0	0	0
9J.Crawford, CF	0-3	0	0	0