Guardians vs. Twins Odds & Betting Predictions - May 21, 2025

Guardians at Twins

5:10 pm • CLEG
5 - 6
Starting Pitchers
pitcherteameraw-l
Bailey Ober logoB.OberMinnesota Twins logo5.384-6
Logan Allen logoL.AllenCleveland Guardians logo4.067-9

Guardians at Twins Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
56-54
+1.5
+1.5+105
o11.5-120
+125
Twins
51-59
u6.5
-1.5-139
u11.5-115
-154
location pinWednesday 5:10 p.m.
May 21, 2025
Target FieldMinneapolis
Guardians vs. Twins Expert Picks
Steak Friend
Steak Friend
Last 30d: 0-0-0 (+0.0u)
MIN -110
1u

Guardians vs. Twins Previews & Analysis

  • 3 MLB Player Props for Wednesday article feature image

    3 MLB Player Props for Wednesday

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Prop Odds Comparison

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Line Movement Tracker

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Guardians vs. Twins Public Betting Percentages

Away Logo

Guardians

Public

23%

Bets%

77%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Twins
55-5528-2627-2933-3721-18
Guardians
56-5426-2930-2523-2333-30

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Twins
45-60-524-28-221-32-330-37-314-23-2
Guardians
48-58-427-27-121-31-324-2224-35-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Twins
51-5930-2421-3537-3314-25
Guardians
56-5429-2627-2830-1626-37

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 18th@MILL 2-5+1.5 LU 7.5MIL +123
May 17th@MILW 7-0-1.5 WU 7.5MIN -125
May 17th@MILW 3-0-1.5 WU 7.5MIN -120
May 15th@BALW 4-0+1.5 WU 9MIN +112
May 14th@BALW 8-6+1.5 WO 9MIN +120

Guardians vs. Twins Injury Updates

Guardians Injuries

  • Ben Lively
    SP

    Lively is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Twins Injuries

  • Byron Buxton
    CF

    Buxton is out with ribs

    Out

Guardians vs. Twins Box Score
Guardians Player Stats
Projected
PITCHERPCIPKER
Logan Allen logoLL.Allen, P53332
Jakob Junis logoRJ.Junis, P411.202
Joey Cantillo logoLJ.Cantillo, P432.140
Kolby Allard logoLK.Allard, P22111
Cade Smith logoRC.Smith, P150.201
HITTERSH-ABRHRRBI
Steven Kwan logo1S.Kwan, LF1-4000
Angel Martinez logo2A.Martinez, 2B1-4100
Angel Martinez logo2A.Martinez, CF1-4100
Jose Ramirez logo3J.Ramirez, 3B1-4100
Kyle Manzardo logo4K.Manzardo, DH1-3001
Carlos Santana logo5C.Santana, 1B1-4211
Nolan Jones logo6N.Jones, CF1-4101
Nolan Jones logo6N.Jones, RF1-4101
Gabriel Arias logo7G.Arias, SS0-4000
Bo Naylor logo8B.Naylor, C1-4002
Will Brennan logo9W.Brennan, RF1-2000
Daniel Schneemann logo9D.Schneemann, PH0-1000
Daniel Schneemann logo9D.Schneemann, 2B0-1000
Twins Player Stats
Projected
PITCHERPCIPKER
Bailey Ober logoRB.Ober, P42331
Joe Ryan logoRJ.Ryan, P89543
Jhoan Duran logoRJ.Duran, P23111
HITTERSH-ABRHRRBI
Ryan Jeffers logo1R.Jeffers, C1-2100
Brooks Lee logo2B.Lee, SS0-4000
Royce Lewis logo3R.Lewis, DH1-4000
Ty France logo4T.France, 1B1-4001
Ryan Fitzgerald logo4R.Fitzgerald, PR0-0100
Trevor Larnach logo5T.Larnach, LF2-4100
Trevor Larnach logo5T.Larnach, RF2-4100
DaShawn Keirsey logo5D.Keirsey, PR0-1100
DaShawn Keirsey logo5D.Keirsey, LF0-1100
Jonah Bride logo6J.Bride, 3B3-5000
Carson McCusker logo7C.McCusker, RF0-1000
Kody Clemens logo7K.Clemens, PH2-3102
Kody Clemens logo7K.Clemens, 2B2-3102
Harrison Bader logo8H.Bader, CF1-3102
Willi Castro logo9W.Castro, 2B1-3001
Willi Castro logo9W.Castro, LF1-3001
Willi Castro logo9W.Castro, RF1-3001

Guardians vs. Twins Odds Comparison

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Guardians at Twins Team Totals

MatchupOverUnder
Guardians
56-54
N/A
N/A
Twins
51-59
N/A
N/A