Guardians vs. Twins Odds & Betting Predictions - September 20, 2025

Guardians at Twins

12:10 am • CLEG

Cleveland Guardians

6

6 - 2

Minnesota Twins

2

pitcher		team	era	w-l
P.Lopez			2.74	5-4
P.Messick			2.72	3-1

MatchupOpenSpreadTotalMoneyline
Guardians 15-12	+1.5	-1.5+146	o7.5-124	-113
Twins 12-14	u8	+1.5-186	u7.5-102	-108

location pin

Saturday 12:10 a.m.

September 20, 2025

Target FieldMinneapolis

Over 8+100

2u

J.Ramirez o1.5 Total Bases-110

$1.00

CLE -110

$1.00

Under 8-120

1u

@cowhitchurch Best Bet https://myaction.app/7E4QiBJkNWb

CLE +100

0.5u

CLE +105

0.53u

Bet to -102

Under 8-115

0.58u

Guardians vs Twins: Pitcher's Duel For Friday Night
Collin Whitchurch•
Sep 19, 2025 UTC

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MLB Public Betting

Twins are 1-4 in their last 5 games.
Twins are 2-3 in their last 5 games against the spread
Twins are 7-6 in their road games against the spread
The totals have gone OVER in 4 of Twins' last 5 games
The totals have gone OVER in 7 of Twins' 13 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Twins	14-12	7-6	7-6	2-5	12-7
Guardians	16-11	9-4	7-7	8-5	8-6

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Twins	15-10-1	7-5-1	8-5	5-2	10-8-1
Guardians	14-13	6-7	8-6	7-6	7-7

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Twins	12-14	7-6	5-8	2-5	10-9
Guardians	15-12	8-5	7-7	8-5	7-7

date	opponent	score	spread	over/under	moneyline
Sep 17th	NYY	L 5-10	+1.5 L	O 9.5	NYY +134
Sep 16th	NYY	L 9-10	+1.5 W	O 9	NYY +144
Sep 15th	NYY	W 7-0	+1.5 W	U 9	MIN +163
Sep 14th	ARI	L 4-6	-1.5 L	O 9.5	ARI -125
Sep 13th	ARI	L 2-5	-1.5 L	U 8.5	ARI -135

Steven Kwan
LF
Steven Kwan scratched Saturday
Out

Pablo Lopez
SP
Lopez is out with elbow
Out
David Festa
SP
Festa is out with shoulder
Out
Travis Adams
SP
Adams is out with triceps
Out

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PITCHER		PC	IP	K	ER
LP.Messick, P		94	5.1	9	2
RM.Festa, P		12	0.2	2	0
RJ.Junis, P		27	2	4	0
RC.Smith, P		12	1	1	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, LF	2-5	2	0	1
2A.Martinez, CF	1-5	0	0	1
3J.Ramirez, 3B	1-3	2	0	0
4K.Manzardo, 1B	0-3	1	0	0
4N.Jones, RF	0-0	0	0	0
4D.Schneemann, PH	0-1	0	0	0
4D.Schneemann, RF	0-1	0	0	0
5B.Naylor, C	2-4	0	0	4
6G.Arias, SS	1-4	0	0	0
7G.Valera, DH	1-1	0	0	0
7D.Fry, PH	1-2	1	0	0
7D.Fry, DH	1-2	1	0	0
8C.Kayfus, RF	0-2	0	0	0
8J.Noel, PH	0-2	0	0	0
8J.Noel, RF	0-2	0	0	0
8J.Noel, 1B	0-2	0	0	0
9B.Rocchio, 2B	0-4	0	0	0

PITCHER		PC	IP	K	ER
RP.Lopez, P		61	4	2	2
RC.Laweryson, P		20	2	2	0
LK.Funderburk, P		20	1.1	3	0
RC.Sands, P		25	0.2	2	2
RM.Tonkin, P		17	1	1	2

HITTERS	H-AB	R	HR	RBI
1B.Buxton, CF	0-4	0	0	0
2A.Martin, LF	1-4	1	0	0
3L.Keaschall, 2B	1-4	1	0	0
4B.Lee, SS	0-4	0	0	0
5R.Lewis, 3B	2-4	0	0	1
6K.Clemens, 1B	1-4	0	0	0
7C.McCusker, DH	1-2	0	0	0
7T.Larnach, PH	0-1	0	0	0
7T.Larnach, DH	0-1	0	0	0
8J.Pereda, C	0-2	0	0	0
8E.Julien, PH	0-1	0	0	0
8M.Gasper, C	0-1	0	0	0
9J.Outman, RF	0-2	0	0	0

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MatchupOverUnder
Guardians 15-12	N/A	N/A
Twins 12-14	N/A	N/A