Padres vs. White Sox Odds & Betting Predictions - September 21, 2025

Padres at White Sox

6:10 pm • SDPA

San Diego Padres

3

3 - 2

Chicago White Sox

2

pitcher		team	era	w-l
S.Burke			4.29	4-11
M.King			3.57	5-3

MatchupOpenSpreadTotalMoneyline
Padres 87-71	-1.5	-1.5-105	o8-119	-180
White Sox 58-99	u8	+1.5-115	u8+100	+150

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Sunday 6:10 p.m.

September 21, 2025

Rate FieldChicago

CWS +158

0.5u

Bet to +145

No props found

MLB Public Betting

White Sox are 1-4 in their last 5 games.
White Sox are 3-2 in their last 5 games against the spread
White Sox are 45-31 in their road games against the spread
The totals have gone OVER in 1 of White Sox' last 5 games
The totals have gone OVER in 42 of White Sox' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
White Sox	92-65	47-34	45-31	0-2	90-63
Padres	84-74	42-35	42-39	41-48	42-26

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
White Sox	72-78-7	42-34-5	30-44-2	0-2	70-76-7
Padres	67-87-4	32-44-1	35-43-3	44-43-2	23-43-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
White Sox	58-99	33-48	25-51	1-1	56-97
Padres	87-71	49-28	38-43	53-36	33-35

date	opponent	score	spread	over/under	moneyline
Sep 20th	SD	L 3-7	+1.5 L	O 8	SD +153
Sep 19th	SD	W 4-3	-	-	-
Sep 17th	BAL	L 1-3	+1.5 L	U 8.5	BAL +104
Sep 16th	BAL	L 7-8	+1.5 W	O 8	BAL -110
Sep 15th	BAL	L 1-4	+1.5 L	U 8	BAL +117

Ky Bush
SP
Bush is out with elbow
Out
Drew Thorpe
SP
Thorpe is out with elbow
Out

Joe Musgrove
SP
Musgrove is out for season with elbow
Out for Season

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PITCHER		PC	IP	K	ER
RM.King, P		70	5	4	0
LA.Morejon, P		12	1	2	0
LK.Hart, P		13	0.1	1	2
RM.Miller, P		19	0.2	1	0
LW.Peralta, P		17	1	1	0
RR.Suarez, P		11	1	2	0

HITTERS	H-AB	R	HR	RBI
1F.Tatis, RF	2-5	1	1	1
2L.Arraez, 2B	1-3	0	0	0
2L.Arraez, 1B	1-3	0	0	0
3M.Machado, 3B	0-4	0	0	0
4J.Merrill, CF	1-4	1	0	0
5R.Laureano, LF	1-4	0	0	0
6G.Sheets, DH	1-4	1	0	0
7R.O'Hearn, 1B	3-4	0	0	0
7M.McCoy, PR	0-0	0	0	0
7M.McCoy, SS	0-0	0	0	0
8J.Cronenworth, SS	1-4	0	0	1
8J.Cronenworth, 2B	1-4	0	0	1
9E.Diaz, C	0-3	0	0	0
9W.Wagner, PH	0-1	0	0	0
9F.Fermin, C	0-0	0	0	0

PITCHER		PC	IP	K	ER
RS.Burke, P		63	4	4	2
RM.Vasil, P		42	3	3	0
RG.Taylor, P		9	1	2	0
LB.Eisert, P		12	0.1	1	0
RJ.Leasure, P		7	0.2	1	0

HITTERS	H-AB	R	HR	RBI
1C.Meidroth, 2B	0-3	1	0	0
2K.Teel, DH	0-3	0	0	0
3C.Montgomery, SS	1-4	0	0	0
4M.Vargas, 3B	1-4	0	0	1
4M.Vargas, LF	1-4	0	0	1
4M.Vargas, 3B	1-4	0	0	1
5E.Quero, C	1-3	0	0	0
6B.Baldwin, CF	1-1	0	0	0
6C.Mead, PH	0-1	0	0	0
6C.Mead, 3B	0-1	0	0	0
6A.Benintendi, PH	0-0	0	0	1
6K.Lee, PR	0-0	0	0	0
6K.Lee, LF	0-0	0	0	0
7L.Sosa, 1B	0-4	0	0	0
8W.Robertson, LF	0-2	0	0	0
8M.Taylor, PH	0-2	0	0	0
8M.Taylor, CF	0-2	0	0	0
9D.Fletcher, RF	1-3	1	0	0

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MatchupOverUnder
Padres 87-71	o4.5-121	u4.5-107
White Sox 58-99	o3.5+108	u3.5-140