Orioles vs. White Sox Odds & Betting Predictions - September 17, 2025

Orioles at White Sox

6:10 pm • CHSN
Stream Live on SiriusXM - Free 3 Month Offer
@
Starting Pitchers
pitcherteameraw-l
Martin Perez logoM.PerezChicago White Sox logo3.271-5
Tyler Wells logoT.WellsBaltimore Orioles logo2.311-0

Orioles at White Sox Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Orioles
71-80
-1.5
-1.5+134
o8.5-111
-125
White Sox
57-95
u8
+1.5-164
u8.5-108
+104
location pinWednesday 6:10 p.m.
September 17, 2025
Rate FieldChicago
thermometer image77°Fahrenheit
rain image0%Rain
wind image7Wind
Orioles vs. White Sox Expert Picks
Brandon Kravitz
Brandon Kravitz
Last 30d: 22-29-0 (-7.0u)
Under 8-109
0.65u
Allan Lem
Allan Lem
Last 30d: 93-95-9 (-7.6u)
Under 8.5-115
1.15u
Sean Zerillo
Sean Zerillo
Last 30d: 172-183-5 (-2.0u)
BAL -122 (F5)
0.5u
Flat to -135

Orioles vs. White Sox Previews & Analysis

  • Orioles vs White Sox: Expect a Low-Scoring Game article feature image

    Orioles vs White Sox: Expect a Low-Scoring Game

    Action Network Staff
    Sep 17, 2025 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Orioles vs. White Sox Public Betting Percentages

Away Logo

Orioles

Public

79%

Bets%

21%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
White Sox
89-6345-3244-310-287-61
Orioles
73-7834-4039-3823-4048-37

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
White Sox
71-74-741-31-530-43-20-269-72-7
Orioles
63-84-433-39-230-45-231-30-230-53-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
White Sox
57-9532-4525-501-155-93
Orioles
71-8036-3835-4230-3338-47

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 16thBALL 7-8+1.5 WO 8BAL -110
Sep 15thBALL 1-4+1.5 LU 8BAL +117
Sep 14th@CLEL 2-3+1.5 WU 8CLE +130
Sep 13th@CLEL 1-3+1.5 LU 7.5CLE +146
Sep 12th@CLEL 0-4+1.5 LU 7.5CLE +119

White Sox vs. Orioles Injury Updates

White Sox Injuries

  • Ky Bush
    SP

    Bush is out with elbow

    Out

  • Drew Thorpe
    SP

    Thorpe is out with elbow

    Out

Orioles Injuries

  • Grayson Rodriguez
    SP

    Rodriguez is out with elbow

    Out

Orioles vs. White Sox Starting Lineups
Orioles Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Tyler Wells logoRT.Wells, P1-02.310.6007.71
HITTERSAVGOBPSLGHR
Jackson Holliday logo1J.Holliday, 2B.253.324.39417
Jordan Westburg logo2J.Westburg, 3B.273.327.46915
Gunnar Henderson logo3G.Henderson, SS.272.348.44016
Tyler O'Neill logo4T.O'Neill, DH.208.290.4168
Jeremiah Jackson logo5J.Jackson, RF.290.327.4765
Coby Mayo logo6C.Mayo, 1B.201.281.3639
Dylan Beavers logo7D.Beavers, LF.275.420.4382
Alex Jackson logo8A.Jackson, C.244.311.5245
Jorge Mateo logo9J.Mateo, CF.182.229.2731
White Sox Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Martin Perez logoLM.Perez, P1-53.271.0517.23
HITTERSAVGOBPSLGHR
Chase Meidroth logo1C.Meidroth, 2B.270.347.3435
Mike Tauchman logo2M.Tauchman, DH.263.355.3948
Miguel Vargas logo3M.Vargas, 3B.229.310.39414
Colson Montgomery logo4C.Montgomery, SS.218.292.50518
Edgar Quero logo5E.Quero, C.277.341.3745
Lenyn Sosa logo6L.Sosa, 1B.262.293.42620
Will Robertson logo7W.Robertson, LF.100.250.1000
Michael A. Taylor logo8M.Taylor, CF.206.265.3728
Dominic Fletcher logo9D.Fletcher, RF.231.231.4620

Orioles vs. White Sox Odds Comparison

Right Arrow

Could not load odds

Orioles at White Sox Team Totals

MatchupOverUnder
Orioles
71-80
N/A
N/A
White Sox
57-95
N/A
N/A