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Reds vs. Rays Odds & Betting Predictions - April 22, 2026

Reds at Rays

5:10 pm • RAYS

Cincinnati Reds

42-49
1
1 - 6

Tampa Bay Rays

54-36
6
Starting Pitchers
pitcherteameraw-l
Nick Martinez logoN.MartinezTampa Bay Rays logo2.617-2
Brandon Williamson logoB.WilliamsonCincinnati Reds logo6.112-3

Reds at Rays Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Reds
42-49
+1.5
+1.5-178
o8.5-105
+119
Rays
54-36
u8
-1.5+145
u8.5-112
-140
location pinWednesday 5:10 p.m.
April 22, 2026
Tropicana FieldSt. Petersburg
Reds vs. Rays Expert Picks
Player Prop Savant
Player Prop Savant
Last 30d: 86-67-3 (+17.7u)
Over 7.5 (Live)-135
1.35u
Frank Ammirante
Frank Ammirante
Last 30d: 388-401-8 (-9.8u)
CIN +120
0.83u
Cam Is Money
Cam Is Money
Last 30d: 0-0-0 (+0.0u)
CIN +122
1u
Frank Ammirante
Frank Ammirante
Last 30d: 388-401-8 (-9.8u)
E.De La Cruz o1.5 Hits + Runs + RBIs-114
1.14u
Picks Office
Picks Office
Last 30d: 179-181-15 (-19.2u)
Over 8.5-105
1u
Join Discord. All picks posted before 8am https://discord.gg/HjKxYKdSUy
Doug Ziefel
Doug Ziefel
Last 30d: 153-178-17 (+7.3u)
B.Williamson u15.5 Outs-110
0.5u
Player Prop Savant
Player Prop Savant
Last 30d: 86-67-3 (+17.7u)
E.De La Cruz o1.5 Hits + Runs + RBIs-114
1.14u
RoyalsProps
RoyalsProps
Last 30d: 27-29-0 (-5.8u)
E.De La Cruz o1.5 Hits + Runs + RBIs-110
1.1u
Cam Is Money
Cam Is Money
Last 30d: 0-0-0 (+0.0u)
E.De La Cruz o1.5 Hits + Runs + RBIs-110
1u
Ryan Minion
Ryan Minion
Last 30d: 252-293-19 (-7.7u)
C.Simpson o0.5 SB+400
$0.60
#ACTION ✍️✍️
TB -135 (F5)
$1.00
#ACTION ✍️✍️
C.Simpson o0.5 Runs Scored+175
$1.00
#ACTION ✍️✍️
Anders
Anders
Last 30d: 11-5-1 (+6.3u)
Over 8-110
1.1u
Both starters xERA over 2 runs worse than their actual. Rays pen is a disaster, Reds pen actually just plain ERA wise sits 1st in all of baseball, however that’s just bound to regress. Solid unit, not elite. Just think it’s too low
OldSchool0909
Last 30d: 27-25-0 (+7.2u)
CIN +123
1u
Frank Ammirante
Frank Ammirante
Last 30d: 388-401-8 (-9.8u)
CIN o3.5-120
1.2u
Sean Zerillo
Sean Zerillo
Last 30d: 130-133-8 (-5.9u)
Over 7.5-120
0.6u
Bet to 8 (-115)

Reds vs. Rays Previews & Analysis

  • Minion's SGP for Reds-Rays article feature image

    Minion's SGP for Reds-Rays

    Ryan Minion•
    Apr 22, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Reds vs. Rays Public Betting Percentages

Away Logo

Reds

Public

Home Logo

Rays

61%

Bets%

39%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Rays are 2-3 in their last 5 games.
  • Rays are 2-3 in their last 5 games against the spread
  • Rays are 23-21 in their road games against the spread
  • The totals have gone OVER in 2 of Rays' last 5 games
  • The totals have gone OVER in 19 of Rays' 46 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Rays		54-3631-1523-2135-2318-13
Reds		48-4322-2426-1915-1233-30

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Rays		39-49-219-26-120-23-127-29-212-19
Reds		52-38-126-2026-18-118-934-28-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Rays		54-3633-1321-2338-2015-16
Reds		42-4921-2521-2416-1126-37

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 21stCINL 6-12+1.5 LO 7.5CIN -107
Apr 20thCINL 1-6-U 8CIN -126
Apr 19th@PITL 3-6-O 8PIT -112
Apr 18th@PITW 8-7+1.5 WO 7.5TB +131
Apr 17th@PITL 1-5+1.5 LU 8.5PIT +107

Rays vs. Reds Injury Updates

Rays Injuries

  • Gavin Lux
    LF

    Lux is out with shoulder

    Out

  • Michael Grove
    RP

    Grove is out with shoulder

    Out

Reds Injuries

    See more MLB Injuries Right Arrow
    Reds vs. Rays Box Score
    Reds Player Stats
    Projected
    PITCHERPCIPKER
    Brandon Williamson logoLB.Williamson, P874.135
    Connor Phillips logoRC.Phillips, P29211
    Tony Santillan logoRT.Santillan, P60.200
    Brock Burke logoLB.Burke, P9100
    HITTERSH-ABRHRRBI
    TJ Friedl logo1T.Friedl, CF1-4000
    Matt McLain logo2M.McLain, 2B1-4000
    Elly De La Cruz logo3E.De La Cruz, SS0-4000
    Sal Stewart logo4S.Stewart, 1B1-4000
    Eugenio Suarez logo5E.Suarez, 3B0-4000
    Nathaniel Lowe logo6N.Lowe, DH1-4100
    Spencer Steer logo7S.Steer, LF1-3000
    Will Benson logo8W.Benson, RF0-2000
    P.J. Higgins logo9P.Higgins, C0-2001
    Rays Player Stats
    Projected
    PITCHERPCIPKER
    Nick Martinez logoRN.Martinez, P95861
    Kevin Kelly logoRK.Kelly, P13110
    HITTERSH-ABRHRRBI
    Yandy Diaz logo1Y.Diaz, DH3-4101
    Jonathan Aranda logo2J.Aranda, 1B0-2000
    Junior Caminero logo3J.Caminero, 3B1-4112
    Ryan Vilade logo4R.Vilade, RF2-2101
    Richie Palacios logo4R.Palacios, PH0-1000
    Richie Palacios logo4R.Palacios, RF0-1000
    Jonny DeLuca logo5J.DeLuca, CF0-3100
    Ben Williamson logo6B.Williamson, 2B1-4101
    Chandler Simpson logo7C.Simpson, LF1-3001
    Nick Fortes logo8N.Fortes, C0-3000
    Taylor Walls logo9T.Walls, SS1-3100

    Reds vs. Rays Odds Comparison

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    Reds at Rays Team Totals

    MatchupOverUnder
    Reds
    42-49
    N/A
    N/A
    Rays
    54-36
    N/A
    N/A