White Sox vs. Cubs Odds & Betting Predictions - May 17, 2025

White Sox at Cubs

6:20 pm • MARQ
3 - 7
Starting Pitchers
pitcherteameraw-l
Matthew Boyd logoM.BoydChicago Cubs logo2.3411-4
Sean Burke logoS.BurkeChicago White Sox logo4.174-8

White Sox at Cubs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
White Sox
42-69
+1.5
+1.5+135
o10-105
+260
Cubs
64-46
u10.5
-1.5-162
u10-115
-322
location pinSaturday 6:20 p.m.
May 17, 2025
Wrigley FieldChicago
White Sox vs. Cubs Expert Picks
The Degenerates
The Degenerates
Last 30d: 53-42-3 (+6.4u)
CHC -1.5-148
1u
Royals Props
Royals Props
Last 30d: 0-0-0 (+0.0u)
M.Busch o1.5 Hits + Runs + RBIs-120
1.2u
Austin Pendergrass
Austin Pendergrass
Last 30d: 38-62-0 (-13.2u)
CHC -1.5-134
0.75u
CWS are awful but they’re even worse against LHP hitting a combined .224 against lefties. They also hit a combined .205 during day games so everything is against them today. Expect Cubs to pour it on
💰🦡 Jake
💰🦡 Jake
Last 30d: 45-50-1 (-2.7u)
CWS +200 (F5)
0.25u
CWS +1.5 (F5)-125
1.25u
Sean Zerillo
Sean Zerillo
Last 30d: 139-156-9 (+3.2u)
Under 10.5-120
0.5u
Bet to 10 (-106)

Prop Odds Comparison

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Line Movement Tracker

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White Sox vs. Cubs Public Betting Percentages

Away Logo

White Sox

Public

7%

Bets%

93%

Money%

MLB Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cubs
53-5725-2928-2839-3714-20
White Sox
65-4632-2433-220-265-44

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cubs
56-49-528-24-228-25-337-36-319-13-2
White Sox
49-56-629-22-520-34-10-249-54-6

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cubs
64-4634-2030-2651-2513-21
White Sox
42-6924-3218-371-141-68

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 16thCWSW 13-3-1.5 WO 11.5CHC -231
May 14thMIAL 1-3-1.5 LU 7.5MIA -218
May 13thMIAW 5-4-1.5 LO 8CHC -262
May 12thMIAW 5-2-1.5 WU 8CHC -257
May 11th@NYML 2-6+1.5 LU 8.5NYM +110

White Sox vs. Cubs Injury Updates

White Sox Injuries

  • Ky Bush
    SP

    Bush is out with elbow

    Out

  • Drew Thorpe
    SP

    Thorpe is out with elbow

    Out

  • Shane Smith
    SP

    Smith is out with ankle

    Out

Cubs Injuries

  • Jameson Taillon
    SP

    Taillon is out with calf

    Out

  • Justin Steele
    SP

    Steele is out for season with elbow

    Out for Season

White Sox vs. Cubs Box Score
White Sox Player Stats
Projected
PITCHERPCIPKER
Sean Burke logoRS.Burke, P974.245
Cam Booser logoLC.Booser, P70.110
Jared Shuster logoLJ.Shuster, P90.200
Mike Vasil logoRM.Vasil, P462.121
HITTERSH-ABRHRRBI
Chase Meidroth logo1C.Meidroth, SS3-4111
Miguel Vargas logo2M.Vargas, 3B0-3001
Edgar Quero logo3E.Quero, C0-4000
Luis Robert logo4L.Robert, CF0-4000
Andrew Vaughn logo5A.Vaughn, DH1-4000
Lenyn Sosa logo6L.Sosa, 2B0-3000
Matt Thaiss logo6M.Thaiss, PH0-1000
Tim Elko logo7T.Elko, 1B1-2111
Josh Rojas logo7J.Rojas, PH0-1000
Joshua Palacios logo8J.Palacios, RF0-3000
Michael A. Taylor logo9M.Taylor, LF1-2100
Brooks Baldwin logo9B.Baldwin, PH0-1000
Brooks Baldwin logo9B.Baldwin, LF0-1000
Cubs Player Stats
Projected
PITCHERPCIPKER
Matthew Boyd logoLM.Boyd, P92683
Brad Keller logoRB.Keller, P20110
Daniel Palencia logoRD.Palencia, P17120
Porter Hodge logoRP.Hodge, P18110
HITTERSH-ABRHRRBI
Pete Crow-Armstrong logo1P.Crow-Armstrong, CF2-5002
Kyle Tucker logo2K.Tucker, RF0-2000
Seiya Suzuki logo3S.Suzuki, LF1-5000
Michael Busch logo4M.Busch, 1B0-4000
Dansby Swanson logo5D.Swanson, SS2-3311
Moises Ballesteros logo6M.Ballesteros, DH0-2100
Justin Turner logo6J.Turner, PH0-1000
Justin Turner logo6J.Turner, DH0-1000
Nico Hoerner logo7N.Hoerner, 2B2-3201
Miguel Amaya logo8M.Amaya, C1-4102
Vidal Brujan logo9V.Brujan, 3B1-4001
Nicky Lopez logo9N.Lopez, 3B0-1000

White Sox vs. Cubs Odds Comparison

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White Sox at Cubs Team Totals

MatchupOverUnder
White Sox
42-69
o3.5-111
u3.5-116
Cubs
64-46
o6-113
u6-113