The Detroit Tigers host the Boston Red Sox on May 5, 2026. First pitch from Comerica Park is scheduled for 6:40 p.m. ET. The game will be broadcast on NESN.
The Tigers are favored by -174 on the moneyline and by -1.5 on the run line. The Red Sox are +146 on the moneyline and +1.5 on the run line. The total is set at 8 runs.
Find my MLB picks and Red Sox vs Tigers prediction below, as well as probable pitchers, weather report, and more.
Red Sox vs Tigers Prediction
- Red Sox vs Tigers Pick: Over 8 (-118)
My Red Sox vs Tigers best bet is Over 8 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.
Red Sox vs Tigers Odds
| Red Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -142 | 8 -118o / -104u | +146 |
| Tigers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +118 | 8 -118o / -104u | -174 |
- Red Sox vs Tigers moneyline: Red Sox +146, Tigers -174
- Red Sox vs Tigers over/under: 8 (-118o / -104u)
- Red Sox vs Tigers spread: Red Sox +1.5 (-142), Tigers -1.5 (+118)
Red Sox vs Tigers Probable Pitchers
| LHP Jovani Moran (BOS) | Stat | LHP Framber Valdez (DET) |
|---|---|---|
| 0-0 | W-L | 2-1 |
| 0.0 | fWAR (FanGraphs) | 0.8 |
| 2.33 / 3.29 | ERA / xERA | 3.35 / 3.74 |
| 4.59 / 5.23 | FIP / xFIP | 3.39 / 4.05 |
| 7.6 | K-BB% | 10.4 |
| 34.7 | GB% | 51.2 |
| .167 | BABIP | .285 |
| 96 | Stuff+ | 104 |
| 93 | Location+ | 99 |
Red Sox vs Tigers MLB Betting Preview, Prediction
Editor's Note: This written article is a transcription from the latest episode of the Payoff Pitch podcast.
I'm going with Over 8 in this matchup between the Red Sox and Tigers, and I would actually look at the live bet as well, with both Detroit and the over once Brayan Bello comes into the game, because I have Bello ranked 154th out of 160 starters this season.
I don't think I've seen anybody worse, though. Bello is at 8.1 expected ERA, 6.2 expected FIP, 5.4 SIERA and a 1.5% strikeout minus walk rate.
His velocity is down. His Pitching+ and Stuff+ ratings are down.
Bello is getting absolutely lit up this season, and the Red Sox are trying to protect him by using Jovani Moran as an opener tonight. Presumably, Bello will enter the game after.
So I would look at Over 8 pregame, and then the Tigers and the over live as Bello enters tonight.
Pick: Over 8 (-118, FanDuel)
