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Brewers vs Cubs Prediction, Pick, Odds: Contrarian Over/Under Angle

Brewers vs Cubs Prediction, Pick, Odds: Contrarian Over/Under Angle article feature image
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Pictured: Ian Happ (Left)/ Seiya Suzuki (Right)

The Chicago Cubs host the Milwaukee Brewers on May 18, 2026. First pitch from Wrigley Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on BREW.

The Cubs are favored by -165 on the moneyline and by -1.5 on the run line. The Brewers are +135 on the moneyline and +1.5 on the run line. The total is set at 10.5 runs.

Find my MLB picks and Brewers vs Cubs prediction below, as well as probable pitchers, weather report, and more.


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Brewers vs Cubs Prediction

  • Brewers vs Cubs Pick: Under 10.5 (-105 or Better)

My Brewers vs Cubs best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.


Brewers vs Cubs Odds

Brewers Logo
Monday, May 18
7:40 p.m. ET
BREW
Cubs Logo
Brewers Odds
SpreadTotalMoneyline
+1.5
-130
10.5
-115o / -105u
+140
Cubs Odds
SpreadTotalMoneyline
-1.5
+110
10.5
-115o / -105u
-165
Odds via bet365. Get up-to-the-minute MLB odds here.
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  • Brewers vs Cubs moneyline: Brewers +135, Cubs -165
  • Brewers vs Cubs over/under: 10.5 (-115o / -105u)
  • Brewers vs Cubs spread: Cubs -1.5 (+111 ), Brewers +1.5 (-133)

Brewers vs Cubs Probable Pitchers

Brandon Sproat (RHP)StatShota Imanaga (LHP)
1-2W-L4-3
-0.3fWAR (FanGraphs)1.6
5.75/4.81ERA / xERA2.32/2.90
5.73/4.45FIP / xFIP2.84/3.25
10.4K-BB%21.8
40GB%36.2
.303BABIP.231
101Stuff+95
93Location+106

Brewers vs Cubs MLB Betting Preview

Editor’s Note: This written pick is a transcription from today's episode of the Payoff Pitch Podcast.

A lot of people are expecting a slugfest in this matchup between the Brewers and Cubs because the wind is blowing out at Wrigley today. Everyone’s assuming it’s going to be a 12-11 type of game, but it’s not quite that extreme.

It’s only going to be in the low 70s, dropping into the high 60s. The wind is blowing out at about 14 mph — not the 20+ mph days where we see totals pushed up to 12.5 or 13. I make this total right around 9.7. I’m betting the Under 10.5 down to -105 (or better). I’d also take Under 10 at even money.

We’ll need to monitor the umpire, but I also like both bullpens in this spot. Shota Imanaga is the type of pitcher who has traditionally struggled in this kind of environment, but his stuff has taken a step forward this year. His command and control of the strike zone have improved as well.

Even though the weather is boosting offense — I’ve added roughly a 20-25% boost to my neutral-weather projection — I’m still about a full run below the market total. On a normal weather day at Wrigley, I’d have this game closer to 7.5. I’ve added nearly two runs for the wind, and I’m still coming in under 10.

I hate betting wind-out Unders at Wrigley because it’s very contrarian, and when it loses, you look silly. But this feels like a good spot to take one today.

Pick: Under 10.5 (-105 or Better)


Brewers vs Cubs Weather


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About the Author

Sean graduated from the University of Miami and Hofstra University Law School, later passing the New York State Bar Exam in 2014. He shifted from a legal career to sports data and betting, joining the Action Network in 2019 after working as a baseball video scout and in financial regulatory compliance. As a senior writer and betting analyst, Sean provides MLB and MMA projections using proprietary models and contributes to various digital content and podcasts, becoming a leading expert in betting for baseball, MMA, and horse racing.

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