The Los Angeles Angels host the Chicago White Sox on May 6, 2026. First pitch from Angel Stadium is scheduled for 4:07 p.m. ET. The game will be broadcast on ABTV.
The White Sox are -108 on the moneyline and are favored by -1.5 on the run line. The Angels are -108 on the moneyline and +1.5 on the run line. The total is set at 9 runs.
Find our MLB picks and White Sox vs Angels prediction below, as well as probable pitchers, weather report, and more.
White Sox vs Angels Prediction
- White Sox vs Angels Pick: Angels ML (-108)
Our White Sox vs Angels best bet is on Los Angeles to win outright. Make sure to find the best odds by checking our live MLB odds page.
White Sox vs Angels Odds
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +152 | 9 -105o / -115u | -108 |
| Angels Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -184 | 9 -105o / -115u | -108 |
- White Sox vs Angels moneyline: White Sox -108, Angels -108
- White Sox vs Angels over/under: 9 (-105o / -115u)
- White Sox vs Angels spread: White Sox -1.5 (+152), Angels +1.5 (-184)
White Sox vs Angels Probable Pitchers
| LHP Noah Schultz (CHW) | Stat | RHP Walbert Urena (LAA) |
|---|---|---|
| 2-1 | W-L | 0-3 |
| 0.5 | fWAR (FanGraphs) | 0.2 |
| 2.53 / 3.37 | ERA / xERA | 3.86 / 3.41 |
| 3.57 / 4.43 | FIP / xFIP | 4.25 / 5.02 |
| 9.4 | K-BB% | 5.1 |
| 34.6 | GB% | 50.0 |
| .173 | BABIP | .333 |
| 100 | Stuff+ | 104 |
| 99 | Location+ | 99 |
White Sox vs Angels MLB Betting Preview
Our own Sean Zerillo projects an edge on the Angels moneyline for this matchup.
While the consensus line sits at -106, Zerillo projects them around -125, representing a 4% edge against the market, making the Angels ML the best choice with a B- grade on our system.
The number of bets might favor Chicago based on last week's winning streak, but sharps have been supporting Los Angeles, as the percentage of money shows an increased interest in this option heading into today's first pitch.
As a reminder, you can see all of Zerillo's MLB game projections with an Action PRO Subscription. Find his projected lines every day on the PRO Projections tab.
White Sox vs Angels Pick, Betting Analysis
The matchups are interesting for this afternoon.
While both lineups are in the middle of the pack in wRC+, tied at 15th with a 98 rating, the Angels do better against left-handed pitchers like Noah Schultz, going up to 12th in that stat category.
On the Angels, Mike Trout, Jo Adell and Oswald Peraza all have over .950 OPS versus southpaws this season, and this will be a good time to test the opposing rookie.
Meanwhile, the White Sox go the other way versus RHP, ranking 23rd in wRC+, and they will face Walbert Urena today.
Los Angeles is counting on Trout to keep producing and on Zach Neto to bounce back, as he did in yesterday's game with a 2-for-4 showing, including a homer.
Pick: Angels ML (-108, FanDuel)
