The Chicago White Sox host the Chicago Cubs on May 15, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on MARQ.
The Cubs are favored by -150 on the moneyline and by -1.5 on the run line. The White Sox are +125 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find my MLB picks and Cubs vs White Sox prediction below, as well as probable pitchers, weather report, and more.
Cubs vs White Sox Prediction
- Cubs vs White Sox Pick: Dansby Swanson To Hit a Home Run (+680 at Draftkings)
My Cubs vs White Sox best bet is on Dansby Swanson to hit a homer. Make sure to find the best odds by checking our live MLB odds page.
Cubs vs White Sox Odds
| Cubs Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -135 | 8.5 -109o / -110u | -150 |
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +114 | 8.5 -109o / -110u | +125 |
- Cubs vs White Sox moneyline: Cubs -150, White Sox +125
- Cubs vs White Sox over/under: 8.5 (-109o / -110u)
- Cubs vs White Sox spread: Cubs -1.5 (+114), White Sox +1.5 (-135)
Cubs vs White Sox Probable Pitchers
| RHP Edward Cabrera (CHC) | Stat | RHP Sean Burke (CHW) |
|---|---|---|
| 3-1 | W-L | 2-3 |
| 0.4 | fWAR (FanGraphs) | 0.8 |
| 3.88/4.31 | ERA / xERA | 3.68/3.77 |
| 4.25/3.59 | FIP / xFIP | 3.84/4.05 |
| 14.6% | K-BB% | 14.5% |
| 43.8% | GB% | 39.8% |
| .310 | BABIP | .264 |
| 95 | Stuff+ | 96 |
| 105 | Location+ | 107 |
Cubs vs White Sox MLB Betting Pick, Betting Analysis
This one is more of a bet against Sean Burke than anything else.
Burke's surface numbers have been great this year, but under the hood, they are not that good. His xFIP and pCRA are actually kind of in line with his ERA this year. However, much of this is due to his walk rate and home runs per fly ball being lower than we can expect going forward.
This is a guy who gives up a good amount of contact to begin with, so I expect him to give up many more home runs than he's been doing so far.
I like Swanson against him getting a nice park upgrade here, too.
We sometimes think of Wrigley Field as more of a hitters' park, especially because once it gets warmer, the wind starts blowing out. But when you neutralize for wind and weather, this is a park that suppresses home runs by about 5%, going into a park that boosts home runs by about 10%.
That'll be a nice little park swing for Swanson, facing a pitcher that's definitely exploitable, giving us good odds on it.
Pick: Dansby Swanson To Hit a Home Run (+680 at Draftkings)
